mercaptoethanol has been researched along with Ovarian Neoplasms in 11 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ifosfamide (isophosphamide) and mesna (2-mercaptoethane sodium sulfonate) were administered intravenously at monthly intervals to 46 patients with advanced epithelial ovarian carcinoma refractory to or recurrent after cisplatin-containing combination chemotherapy." | 9.06 | Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study. ( Berman, ML; Blessing, JA; Homesley, HD; Malfetano, J; Sutton, GP, 1989) |
| "Ifosfamide (isophosphamide) and mesna (2-mercaptoethane sodium sulfonate) were administered intravenously at monthly intervals to 46 patients with advanced epithelial ovarian carcinoma refractory to or recurrent after cisplatin-containing combination chemotherapy." | 5.06 | Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study. ( Berman, ML; Blessing, JA; Homesley, HD; Malfetano, J; Sutton, GP, 1989) |
| "Ifosfamide/mesna has activity in a wide range of gynecologic malignancies." | 1.28 | Early phase II Gynecologic Oncology Group experience with ifosfamide/mesna in gynecologic malignancies. ( Berman, ML; Blessing, JA; Homesley, HD; Photopulos, G; Sutton, GP, 1990) |
| "A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion." | 1.28 | Severe renal failure following high-dose ifosfamide and mesna. ( de Jong, PE; Elema, JD; Mulder, NH; Willemse, PH, 1989) |
| "Ifosfamide/mesna has activity in a wide range of gynecologic malignancies." | 1.28 | Phase II experience with ifosfamide/mesna in gynecologic malignancies: preliminary report of Gynecologic Oncology Group studies. ( Berman, ML; Blessing, JA; Homesley, HD; Photopulos, G; Sutton, GP, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, F | 1 |
| Ha, JH | 1 |
| Yan, Y | 1 |
| Ton, SB | 1 |
| Wang, C | 1 |
| Mutembei, B | 1 |
| Alhajeri, ZA | 1 |
| McNiel, AF | 1 |
| Keddissi, AJ | 1 |
| Zhang, Q | 1 |
| Jayaraman, M | 1 |
| Dhanasekaran, DN | 1 |
| Tang, Q | 1 |
| D'Hollander, A | 1 |
| Jans, H | 1 |
| Velde, GV | 1 |
| Verstraete, C | 1 |
| Massa, S | 1 |
| Devoogdt, N | 1 |
| Stakenborg, T | 1 |
| Muyldermans, S | 1 |
| Lagae, L | 1 |
| Himmelreich, U | 1 |
| Burkert, H | 1 |
| Schnitker, J | 1 |
| Fichtner, E | 1 |
| Willemse, PH | 2 |
| vd Burg, ME | 1 |
| vd Gaast, A | 1 |
| Neijt, JP | 1 |
| ten Bokkel Huinink, WW | 1 |
| Aalders, JG | 1 |
| de Vries, EG | 1 |
| Sutton, GP | 3 |
| Blessing, JA | 3 |
| Photopulos, G | 2 |
| Berman, ML | 3 |
| Homesley, HD | 3 |
| de Jong, PE | 1 |
| Elema, JD | 1 |
| Mulder, NH | 1 |
| Malfetano, J | 1 |
| Li, GC | 1 |
| Brock, N | 1 |
| Li, JQ | 1 |
| Guan, ZZ | 1 |
| He, YJ | 1 |
| Fuller, GM | 1 |
| Rasco, MA | 1 |
| McCombs, ML | 1 |
| Barnett, DR | 1 |
| Bowman, BH | 1 |
| Black, JA | 1 |
| Chan, GF | 1 |
| Hew, CL | 1 |
| Dixon, GH | 1 |
1 trial available for mercaptoethanol and Ovarian Neoplasms
| Article | Year |
|---|---|
Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study.
Topics: Carcinoma; Drug Evaluation; Female; Humans; Ifosfamide; Leukocyte Count; Mercaptoethanol; Mesna; Mul | 1989 |
10 other studies available for mercaptoethanol and Ovarian Neoplasms
| Article | Year |
|---|---|
Optical Coherence Tomography of Tumor Spheroids Identifies Candidates for Drug Repurposing in Ovarian Cancer.
Topics: Drug Repositioning; Female; Humans; Mercaptoethanol; Ovarian Neoplasms; Tomography, Optical Coherenc | 2023 |
Limiting the protein corona: A successful strategy for in vivo active targeting of anti-HER2 nanobody-functionalized nanostars.
Topics: Animals; Cell Line, Tumor; CHO Cells; Cricetulus; Drug Delivery Systems; Female; Gold; Humans; Merca | 2017 |
[Prevention of urinary tract toxicity of oxazaphosphorines by a "uroprotector". Report on a field study (author's transl)].
Topics: Adolescent; Adult; Aged; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Gastrointestinal Dise | 1979 |
Ifosfamide given as a 24-h infusion with mesna in patients with recurrent ovarian cancer: preliminary results.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Ifosfamide; Infusions, Intravenous; | 1990 |
Early phase II Gynecologic Oncology Group experience with ifosfamide/mesna in gynecologic malignancies.
Topics: Antineoplastic Agents; Carcinoma; Drug Evaluation; Female; Humans; Ifosfamide; Mercaptoethanol; Mesn | 1990 |
Severe renal failure following high-dose ifosfamide and mesna.
Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma; Dose-Respons | 1989 |
Phase II experience with ifosfamide/mesna in gynecologic malignancies: preliminary report of Gynecologic Oncology Group studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Carcinoma, Squamous Cell; Ci | 1989 |
Ifosfamide and Mesna in advanced malignancies.
Topics: Adult; Aged; Carcinoma, Bronchogenic; Female; Hematuria; Humans; Ifosfamide; Lung Neoplasms; Lymphom | 1988 |
Subunit composition of haptoglobin 2-2 polymers.
Topics: Amino Acids; Ascitic Fluid; Disulfides; Electrophoresis, Polyacrylamide Gel; Female; Haptoglobins; H | 1973 |
Gene action in the human haptoglobins. 3. Isolation of the alpha-chains as single gene products. Isolation, molecular weight, and amino acid composition of alpha and beta chains.
Topics: Acetamides; Alkylation; Amino Acids; Anhydrides; Ascitic Fluid; Carcinoma; Chemical Phenomena; Chemi | 1970 |