mercaptoethanol has been researched along with Multiple Myeloma in 30 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multiple myeloma is a malignant plasma cell dyscrasia that is becoming more prevalent in an increasingly ageing population." | 1.43 | Multiple myeloma and multiple plasmacytomas associated with free gamma heavy chain, free kappa light chain and IgGk paraproteins: an unusual triple gammopathy. ( Deighan, WI; Keren, DF; McNicholl, FP; O'Kane, MJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (90.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caponi, L | 1 |
| Franzini, M | 1 |
| Koni, E | 1 |
| Masotti, S | 1 |
| Petrini, M | 1 |
| Paolicchi, A | 1 |
| Deighan, WI | 1 |
| O'Kane, MJ | 1 |
| McNicholl, FP | 1 |
| Keren, DF | 1 |
| CUMMINGS, NA | 1 |
| FRANKLIN, EC | 1 |
| GREY, HM | 2 |
| MANNIK, M | 1 |
| KUNKEL, HG | 1 |
| Marshall, T | 1 |
| Gallango, ML | 1 |
| Caldera, LH | 1 |
| Suinaga, R | 1 |
| RamÃrez, M | 1 |
| Tobias, KE | 1 |
| Kahana, C | 1 |
| Laurell, CB | 1 |
| Patterson, R | 2 |
| Roberts, M | 1 |
| Pruzansky, JJ | 1 |
| Andersen, BR | 1 |
| McAninch, JR | 1 |
| Perelmutter, L | 1 |
| Liakopoulou, A | 1 |
| Jones, G | 1 |
| Torrigiani, G | 1 |
| Roitt, IM | 1 |
| Calvanico, NJ | 1 |
| Tomasi, TB | 1 |
| Invernizzi, F | 1 |
| Cattaneo, R | 2 |
| Rosso di San Secondo, V | 1 |
| Balestrieri, G | 2 |
| Zanussi, C | 1 |
| Lind, I | 1 |
| Morse, JH | 1 |
| Ito, C | 1 |
| Hashimoto, I | 1 |
| Onuma, Y | 1 |
| Ishitoya, Y | 1 |
| Apicella, MA | 1 |
| Allen, JC | 1 |
| Ishizaka, T | 1 |
| Ishizaka, K | 1 |
| Bennich, H | 1 |
| Johansson, SG | 1 |
| Wang, AC | 1 |
| Fudenberg, HH | 1 |
| Creyssel, R | 1 |
| Rockey, JH | 1 |
| Schwartzman, RM | 1 |
| Kasukawa, R | 1 |
| Yoshida, H | 1 |
| Yoshida, T | 1 |
| Milgrom, F | 1 |
| Margni, RA | 1 |
| Acerbo, EO | 1 |
| Heer, E | 1 |
| Hajos, SE | 1 |
| Bazzi, C | 1 |
| Simonati, V | 1 |
| Sugai, S | 1 |
| Slavin, RG | 1 |
| Suriano, JR | 1 |
| Dreesman, G | 1 |
| Lee, AK | 1 |
| Mackay, IR | 1 |
| Rowley, M | 1 |
| Marchalonis, JJ | 1 |
| Cone, RE | 1 |
| Santer, V | 1 |
| Ghose, AC | 1 |
| Jirgensons, B | 1 |
| Sher, A | 1 |
| Shalitin, N | 1 |
30 other studies available for mercaptoethanol and Multiple Myeloma
| Article | Year |
|---|---|
Discrepancy between FLC assays: only a problem of quantification?
Topics: Chromatography, Gel; Humans; Immunoassay; Immunoglobulin Light Chains; Mercaptoethanol; Multiple Mye | 2016 |
Multiple myeloma and multiple plasmacytomas associated with free gamma heavy chain, free kappa light chain and IgGk paraproteins: an unusual triple gammopathy.
Topics: Aged; Clonal Evolution; Disease Progression; Electrophoresis, Capillary; Electrophoresis, Polyacryla | 2016 |
ATYPICAL GAMMA-1-A-GLOBULIN WITH THE ELECTROPHORETIC PROPERTIES OF AN ALPHA-2-GLOBULIN OCCURRING IN MULTIPLE MYELOMA.
Topics: Alpha-Globulins; Blood Protein Electrophoresis; Chromatography; Diagnosis, Differential; gamma-Globu | 1965 |
INDIVIDUAL ANTIGENIC SPECIFICITY OF MYELOMA PROTEINS. CHARACTERISTICS AND LOCALIZATION TO SUBUNITS.
Topics: Antigens; Bence Jones Protein; Epitopes; gamma-Globulins; Humans; Immunochemistry; Immunoelectrophor | 1965 |
Sodium dodecyl sulfate polyacrylamide gel electrophoresis of serum after protein denaturation in the presence or absence of 2-mercaptoethanol.
Topics: Animals; Blood Protein Electrophoresis; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Humans; | 1984 |
Co-occurrence of albumin complexes with IgE and IgG in the serum of an IgE myeloma patient.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis, Cellulose Acetate; Guanidine; G | 1982 |
Exposure to ornithine results in excessive accumulation of putrescine and apoptotic cell death in ornithine decarboxylase overproducing mouse myeloma cells.
Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis; Biogenic Polyamines; Cell Size; Cell Survival | 1995 |
Complexes formed in vivo between immunoglobulin light chain kappa, prealbumin and-or alpha-1-antitrypsin in myeloma sera.
Topics: Alpha-Globulins; Animals; Antigen-Antibody Complex; Bence Jones Protein; Blood Platelets; gamma-Glob | 1970 |
Studies of heat precipitable immunoglobulins.
Topics: Alkylation; Chemical Precipitation; gamma-Globulins; Hot Temperature; Humans; Immunodiffusion; Immun | 1970 |
The incidence of precipitating activity in monoclonal proteins.
Topics: Animals; Antigens; Ascaris; Chromatography; Dinitrophenols; gamma-Globulins; Humans; Immunodiffusion | 1971 |
Detection of IgE mediated immediate hypersensitivity reactions in the sera of ragweed sensitive individuals using rat mast cells.
Topics: Animals; Chromatography, DEAE-Cellulose; Cytoplasmic Granules; gamma-Globulins; Hemagglutination Tes | 1971 |
Immunoglobulin determinants on mouse lymphocytes.
Topics: Animals; Antibodies; Antibody Specificity; Antigens; Antilymphocyte Serum; Autoradiography; Chromato | 1971 |
Fragments of human G immunoglobulins produced by a porcine pancreatic esterase.
Topics: Acetamides; Agglutination Tests; Alkylation; Amino Acids; Animals; Antibodies, Anti-Idiotypic; Bindi | 1971 |
Pyroglobulinemia. A report of eight patients with associated paraproteinemia.
Topics: Animals; Blood Protein Disorders; Buffers; Chromatography, DEAE-Cellulose; Cryoglobulins; Electropho | 1973 |
The formation of antibodies against hidden determinants of autologous IgG during immunization of rabbits with Staphylococcus aureus.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Bacterial; Antibody Formation; Antibody Specificity | 1974 |
The aggregation of gamma-myeloma proteins.
Topics: Complement System Proteins; Electrophoresis; gamma-Globulins; Hot Temperature; Humans; Immunochemist | 1965 |
Inhibitory effects of monoclonal immunoglobulins on anti-globulin reaction.
Topics: Amino Acids; Antibodies, Anti-Idiotypic; Bence Jones Protein; Carbohydrates; Chromatography; Coombs | 1968 |
Antigenic specificity of gamma A polymers.
Topics: Antigens; Binding Sites; Blood Proteins; Centrifugation, Density Gradient; Chromatography; Electroph | 1970 |
Biologic activities of aggregated immunoglobulin E.
Topics: Allergens; Animals; Blood Proteins; Chromatography, Gel; Complement Fixation Tests; Cysteine; gamma- | 1970 |
Partial amino acid sequences of variable regions of a human IgG1 (kappa) myeloma protein with anti-rubella activity.
Topics: Alkylation; Amino Acid Sequence; Antibodies, Viral; Autoanalysis; Chromatography, Gel; Cyanogen Brom | 1974 |
Skin sensitizing antibodies: a comparative study of canine and human PK and PCA antibodies and a canine myeloma protein.
Topics: Alkylation; Animals; Antibodies; Centrifugation, Density Gradient; Chromatography; Chromatography, G | 1967 |
Reactions of G-myeloma sera with rheumatoid arthritis sera.
Topics: Animals; Arthritis, Rheumatoid; Complement Inactivator Proteins; Erythrocytes; Guinea Pigs; Hemagglu | 1970 |
The importance of immunochemical analysis in the differential diagnosis of microglobulinic myelomas.
Topics: Aged; Bence Jones Protein; Blood Protein Electrophoresis; Cellulose; Clinical Laboratory Techniques; | 1970 |
[Immunochemical study of 3 cases of pyroglobulinemia].
Topics: Amides; Blood Protein Disorders; Blood Protein Electrophoresis; Blood Proteins; Hot Temperature; Hum | 1970 |
IgA pyroglobulin, hyperviscosity syndrome and coagulation abnormality in a patient with multiple myeloma.
Topics: Blood Coagulation Disorders; Blood Protein Electrophoresis; Blood Proteins; Blood Viscosity; Clot Re | 1972 |
Studies on cryogelglobulinemia associated with IgA myeloma proteins.
Topics: Aged; Animals; Blood Protein Disorders; Blood Viscosity; Bone Marrow Examination; Cryoglobulins; Cyc | 1971 |
Measurement of antibody-producing capacity in man. 3. The response to flagellin from Salmonella adelaide in chronic diseases.
Topics: Adolescent; Adult; Alcoholism; Antibodies; Antibody Formation; Antigens; Bronchitis; Child; Child, P | 1971 |
Enzymic iodination. A probe for accessible surface proteins of normal and neoplastic lymphocytes.
Topics: Animals; Autoradiography; Cell Line; Cell Membrane; Chromatography, Gel; Electrophoresis, Disc; Hydr | 1971 |
Conformational studies on the tryptic digestion fragments of human immunoglobulin G.
Topics: Acetamides; Alkylation; Animals; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Deterg | 1971 |
The subunit structure of mouse IgA.
Topics: Amino Acids; Animals; Autoradiography; Bence Jones Protein; Binding Sites; Carbon Isotopes; Electrop | 1970 |