mercaptoethanol has been researched along with Fanconi Anemia in 2 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Peripheral blood lymphocytes from eight Fanconi anemia (FA) patients, 14 FA heterozygotes, and nine normal subjects have been tested for their susceptibility to chromosomal breakage induction by diepoxybutane (DEB) and by two peroxides." | 3.67 | Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes. ( Alimena, G; Dallapiccola, B; Gandini, E; Isacchi, G; Mokini, V; Porfirio, B, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Porfirio, B | 2 |
| Dallapiccola, B | 2 |
| Mokini, V | 2 |
| Alimena, G | 2 |
| Isacchi, G | 2 |
| Mandelli, F | 1 |
| Gandini, E | 2 |
2 other studies available for mercaptoethanol and Fanconi Anemia
| Article | Year |
|---|---|
[Effects of oxidants and antioxidants on chromosome breaks in Fanconi's anemia].
Topics: Anemia, Aplastic; Antioxidants; Ascorbic Acid; Chromosome Aberrations; Cysteine; Epoxy Compounds; Et | 1983 |
Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes.
Topics: Anemia, Aplastic; Antioxidants; Ascorbic Acid; Cells, Cultured; Chromosome Aberrations; Cross-Linkin | 1985 |