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mercaptoethanol and Experimental Neoplasms

mercaptoethanol has been researched along with Experimental Neoplasms in 44 studies

Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.

Research Excerpts

ExcerptRelevanceReference
" In this study we evaluated the therapeutic activity of combinations of mesna (2-mercaptoethanesulfonate) with cyclophosphamide or Adriamycin in mice with a variety of transplantable tumors (L1210 and P-388 leukemia, Lewis lung and colon 26 carcinoma, B16 melanoma, and M5076 sarcoma)."3.67Combinations of mesna with cyclophosphamide or adriamycin in the treatment of mice with tumors. ( Bansal, SK; Bernacki, RJ; Gurtoo, HL, 1987)
"Lymphoma L5178Y cells were treated with neuraminidase of Vibrio cholerae, potassium iodine, dithiotreitol (DTT), mercaptoethanol, glutaraldehyde, iodoacetamide, merthiolate, sodium periodate, urea, papaine, trypsine and EDTA, to increase immunoreaction in tumor cells."3.65[Immunogenicity of L5178Y cells modified by different reagents]. ( Arellano-Blanco, J; Becerril-Meza, G; Fernández-Quintero, P; Gómez-Estrada, H; López-de la Rosa, LM, 1977)
"Mesna is a pharmacologically unremarkable, physiologically largely inert and almost totally non-toxic thio compound."1.26Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna). ( Brock, N; Pohl, J; Scheef, W; Stekar, J, 1982)
"Six new Marek's disease (MD) lymphoblastoid cell lines were established in vitro by cultivation in a medium containing 2-mercaptoethanol (2-ME)."1.26Establishment of Marek's disease lymphoblastoid cell lines from transplantable versus primary lymphomas. ( Calnek, BW; Murthy, KK; Schat, KA, 1978)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199044 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BRESNICK, E1
BLATCHFORD, K1
Hiserodt, JC1
Britvan, LJ1
Targan, SR1
Heidrick, ML1
Hendricks, LC1
Cook, DE1
Dibner, JJ1
Nakeff, A1
Habs, MR1
Schmähl, D1
Klein, HO1
Wickramanayake, PD1
Christian, E1
Coerper, C1
Graf, L1
Brock, N1
Pohl, J1
Stekar, J1
Scheef, W1
Kikuchi, Y1
Kizawa, I1
Kato, K1
Patel, M1
Havas, HF1
Ogiso, Y1
Kume, A1
Nishimune, Y1
Matsushiro, A1
Oshima, RG1
McKerrow, J1
Cox, D1
Mosbaugh, DW1
Kunkel, TA1
Stalker, DM1
Tcheng, JE1
Meyer, RR1
Igarashi, T2
Okada, M2
Kishimoto, T2
Yamamura, Y2
Nathan, CF1
Terry, WD1
Teranishi, T1
Koren, HS1
Hodes, RJ1
Gómez-Estrada, H1
López-de la Rosa, LM1
Becerril-Meza, G1
Arellano-Blanco, J1
Fernández-Quintero, P1
Hewlett, G1
Opitz, HG1
Flad, HD1
Schlumberger, HD1
Calnek, BW1
Murthy, KK1
Schat, KA1
Warner, NL1
Harris, AW1
McKenzie, IF1
De Luca, D1
Gutman, G1
Altman, A1
Rapp, HJ1
Broome, JD2
Jayaram, HN1
Lombardi, P1
Norata, G1
Maggi, FM1
Canti, G1
Franco, P1
Nicolin, A1
Catapano, AL1
Bernacki, RJ1
Bansal, SK1
Gurtoo, HL1
Wilson, EM1
Wright, BT1
Yarbrough, WG1
Evans, R1
Albrecht, C1
Van Zyl, IM1
Tanino, T2
Sinai, Y1
Reesal, MR1
Tevethia, S1
Silbert, JE1
DeLuca, S1
Pogell, BM1
Tanaka, A1
Siddons, RC1
Buccino, RJ1
Roth, JS1
Kielley, RK1
Tsukada, K1
Hokari, S1
Hayasaki, N1
Ito, N1
Tsumita, T1
Tanabe, K1
Takahashi, T1
Auer, IO1
Tomasi, TB1
Milgrom, F1
Jeng, MW1
McConnell, I1
Burdon, RH1
Garven, EV1
Nariuchi, H1
Usui, M1
Fujimoto, Y1
Hirokawa, K1
Matuhasi, T1
Caputo, A2
Floridi, A2
Marcante, ML1

Other Studies

44 other studies available for mercaptoethanol and Experimental Neoplasms

ArticleYear
STUDIES ON DIHYDROOROTASE ACTIVITY IN PREPARATIONS FROM NOVIKOFF ASCITES HEPATOMA CELLS.
    Archives of biochemistry and biophysics, 1964, Volume: 104

    Topics: Ascites; Carcinoma, Hepatocellular; Cyanides; Cysteine; Dihydroorotase; Enzyme Inhibitors; Hot Tempe

1964
Differential effects of various pharmacological agents on the cytolytic reaction mechanism of the human natural killer lymphocyte: further resolution of programming for lysis and KCIL into discrete stages.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 129, Issue:5

    Topics: Calcium; Cyclic AMP; Cysteine; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Dinoprostone; Dithioth

1982
Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice.
    Mechanisms of ageing and development, 1984, Oct-31, Volume: 27, Issue:3

    Topics: Aging; Animals; Free Radicals; Immunity; Lipid Peroxides; Longevity; Lymphocytes; Male; Mercaptoetha

1984
Proliferative properties of the clonogenic cells of the R3327 prostate adenocarcinoma.
    In vitro, 1983, Volume: 19, Issue:3 Pt 1

    Topics: Adenocarcinoma; Agar; Animals; Cell Count; Cell Division; Cell Line; Erythrocytes; Female; Male; Mer

1983
Prevention of urinary bladder tumors in cyclophosphamide-treated rats by additional medication with the uroprotectors sodium 2-mercaptoethane sulfonate (mesna) and disodium 2,2'-dithio-bis-ethane sulfonate (dimesna).
    Cancer, 1983, Feb-15, Volume: 51, Issue:4

    Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Male; Mercaptoethanol; Mesna; Neoplasms

1983
Therapeutic effects of single-push or fractionated injections of cyclophosphamide or ifosfamide combined with mesna.
    Cancer treatment reviews, 1983, Volume: 10 Suppl A

    Topics: Animals; Cyclophosphamide; Drug Therapy, Combination; Ifosfamide; Male; Mercaptoethanol; Mesna; Mice

1983
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna).
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:12

    Topics: Animals; Cyclophosphamide; Dogs; Drug Interactions; Female; Ifosfamide; Kinetics; Lethal Dose 50; Ma

1982
[Stimulatory effect of 2-mercaptoethanol on tumor bearers with suppressed immune status and its therapeutic effect].
    Nihon Gan Chiryo Gakkai shi, 1982, Oct-20, Volume: 17, Issue:7

    Topics: Animals; Female; Lymphocyte Activation; Mercaptoethanol; Mice; Mice, Inbred C3H; Neoplasms, Experime

1982
The role of T, B and adherent cells in the in vitro immune response of TEPC-183-bearing mice.
    Immunology, 1982, Volume: 46, Issue:1

    Topics: Animals; Antibody Formation; Ascitic Fluid; B-Lymphocytes; Cell Adhesion; Cells, Cultured; Female; I

1982
Effects of beta-mercaptoethanol-containing medium and feeder cells on the differentiation of embryonal carcinoma cells.
    Differentiation; research in biological diversity, 1982, Volume: 22, Issue:3

    Topics: Animals; Cell Differentiation; Cell Line; Clone Cells; Culture Media; Kinetics; Male; Mercaptoethano

1982
Murine embryonal carcinoma hybrids: decreased ability to spontaneously differentiate as a dominant trait.
    Journal of cellular physiology, 1981, Volume: 109, Issue:2

    Topics: Animals; Cell Differentiation; Cell Line; Hybrid Cells; Mercaptoethanol; Mice; Neoplasms, Experiment

1981
Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents.
    Nucleic acids research, 1976, Volume: 3, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; Dithiothreitol; DNA; Escherichia coli; Ethylmaleimide; Guinea Pi

1976
In vitro induction of polyclonal killer T cells with 2-mercaptoethanol and the essential role of macrophages in this process.
    Journal of immunology (Baltimore, Md. : 1950), 1977, Volume: 118, Issue:5

    Topics: Animals; Antigens, Neoplasm; Burkitt Lymphoma; Cell Division; Cells, Cultured; Clone Cells; Cytarabi

1977
Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages.
    The Journal of experimental medicine, 1975, Oct-01, Volume: 142, Issue:4

    Topics: Animals; BCG Vaccine; Carcinoma, Hepatocellular; Cells, Cultured; DNA, Neoplasm; Female; In Vitro Te

1975
LPS-or 8Br-cyclic AMP-induced production of T cell-activating factor(s) in macrophage tumor cell line J774.1.
    Journal of immunology (Baltimore, Md. : 1950), 1978, Volume: 120, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Dose-Response Relationship, Immunol

1978
Effect of tumor cells on the generation of cytotoxic T lymphocytes in vitro. I. Accessory cell functions of mouse tumor cells in the generation of cytotoxic T lymphocytes in vitro: replacement of adherent phagocytic cells by tumor cells or 2-mercaptoethan
    European journal of immunology, 1977, Volume: 7, Issue:6

    Topics: Animals; Antilymphocyte Serum; Ascitic Fluid; Cell Adhesion; Cell Separation; Cells, Cultured; Cytot

1977
[Immunogenicity of L5178Y cells modified by different reagents].
    Archivos de investigacion medica, 1977, Volume: 8, Issue:2

    Topics: Animals; Antibody Formation; Dithiothreitol; Glutaral; Immunity, Cellular; Iodoacetamide; Lymphoma;

1977
Macrophages/monocytes require cell-to-cell contact in order to regulate the growth of a murine lymphoma cell line.
    Journal of immunology (Baltimore, Md. : 1950), 1979, Volume: 123, Issue:5

    Topics: Animals; Cell Communication; Cell Survival; Cell Transformation, Neoplastic; Female; Lymphoma; Macro

1979
Establishment of Marek's disease lymphoblastoid cell lines from transplantable versus primary lymphomas.
    International journal of cancer, 1978, Jan-15, Volume: 21, Issue:1

    Topics: Animals; Antigens, Viral; Cell Line; Cell Membrane; Chickens; Culture Media; Immune Sera; Lymphoma;

1978
Lymphocyte differentiation as analyzed by the expression of defined cell surface markers.
    Advances in experimental medicine and biology, 1978, Volume: 98

    Topics: Binding Sites; Cell Differentiation; Cell Line; Immunoglobulin Fc Fragments; Isoantigens; Lymphocyte

1978
Cytotoxic activity of guinea-pig lymph node cells stimulated in vitro.
    International journal of cancer, 1978, Nov-15, Volume: 22, Issue:5

    Topics: Animals; Ascitic Fluid; Blood; Cells, Cultured; Concanavalin A; Culture Media; Cytotoxicity, Immunol

1978
Studies of the mechanism of growth promotion of lymphoma cells by 2-mercaptoethanol in vitro.
    Acta neuropathologica. Supplementum, 1975, Volume: Suppl 6

    Topics: Animals; Autoradiography; Cell Division; Cells, Cultured; Culture Media; Disulfides; Growth Substanc

1975
Assimilation of LDL by experimental tumours in mice.
    Biochimica et biophysica acta, 1989, Jun-28, Volume: 1003, Issue:3

    Topics: Animals; Biological Transport; Cell Membrane; Edetic Acid; Kinetics; Lipoproteins, LDL; Lipoproteins

1989
Combinations of mesna with cyclophosphamide or adriamycin in the treatment of mice with tumors.
    Cancer research, 1987, Feb-01, Volume: 47, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; Doxoru

1987
The possible role of disulfide bond reduction in transformation of the 10 S androgen receptor.
    The Journal of biological chemistry, 1986, May-15, Volume: 261, Issue:14

    Topics: Animals; Calcium; Dihydrotestosterone; Disulfides; Hot Temperature; Male; Mercaptoethanol; Molybdenu

1986
Phagocytosis of murine lymphoma cells by macrophages. II. Differences between opsonic and cytotoxic activity of mice immunized with lymphoma cells.
    Immunology, 1971, Volume: 20, Issue:1

    Topics: Animals; Antibody Specificity; Antigen-Antibody Reactions; Blood Protein Electrophoresis; Cross Reac

1971
A comparative study of the protein components of ribonucleoprotein particles isolated from rat liver and hepatoma nuclei.
    Experimental cell research, 1973, Volume: 76, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; Electrophoresis, Polyacrylamide Gel; Liver; Liver

1973
Studies on the tumor-host relationship. 3. Chemical and biological properties of serum resistant factor(s).
    The Japanese journal of experimental medicine, 1968, Volume: 38, Issue:5

    Topics: Alpha-Globulins; Animals; Antigen-Antibody Reactions; Beta-Globulins; Blood Protein Electrophoresis;

1968
The induction of a fatal desmoplastic mesothelial reaction in rabbits with mouse Ehrlich ascites carcinomata.
    The Journal of pathology, 1974, Volume: 112, Issue:3

    Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Carcinoma, Ehrlich Tumor; Immune Sera; Immunodiff

1974
Characterization of hamster antibody reacting with papovavirus SV40 tumor antigen.
    Journal of immunology (Baltimore, Md. : 1950), 1967, Volume: 98, Issue:6

    Topics: Animals; Antibodies; Antigens; Centrifugation, Density Gradient; Chromatography; Chromatography, Gel

1967
The synthesis of uridine diphosphate xylose by particulate preparations from mouse mast-cell tumors.
    Biochimica et biophysica acta, 1967, Jun-13, Volume: 141, Issue:1

    Topics: Animals; Anthracenes; Carbon Isotopes; Chromatography; Edetic Acid; Glucose; Glucuronates; Glycine;

1967
Natural activators for liver fructose 1,6-diphosphatase and the reversal of adenosine 5'-monophosphate inhibition by muscle phosphofructokinase.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Aldehyde-Lyases; Animals; Benzoates; Carcinoma, Hepatoc

1968
Partial purification and properties of ATP:GMP phosphransferase from rat liver.
    Archives of biochemistry and biophysics, 1969, Volume: 132, Issue:1

    Topics: Adenosine Triphosphate; Amides; Animals; Benzoates; Carbon Isotopes; Carcinoma, Hepatocellular; Cesi

1969
Purification and properties of thymidine monophosphate kinase from mouse hepatoma.
    The Journal of biological chemistry, 1970, Aug-25, Volume: 245, Issue:16

    Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chemical Precipitation; Ch

1970
Increased activity of polynucleotide ligase from rat hepatoma induced by N-2-fluorenylacetamide.
    Cancer research, 1972, Volume: 32, Issue:5

    Topics: Acetamides; Adenosine Triphosphate; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Nucleus; C

1972
Studies on the tumor-host relationship. IV. Tumor cell agglutination with survival mouse serum.
    The Japanese journal of experimental medicine, 1972, Volume: 42, Issue:4

    Topics: Agglutination; Animals; Calcium; Carbohydrates; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular;

1972
Conversion of DNA polymerase extracted from rat ascites hepatoma cells.
    Biochemical and biophysical research communications, 1973, Jul-02, Volume: 53, Issue:1

    Topics: Animals; Ascitic Fluid; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Chlo

1973
Autoantibodies in NZB mice detected by lysis of DBA-2 lymphoma cells.
    Journal of immunology (Baltimore, Md. : 1950), 1974, Volume: 112, Issue:1

    Topics: Animals; Autoantibodies; Cell Line; Chickens; Cytotoxicity Tests, Immunologic; Hemadsorption; Hemoly

1974
Growth stimulation of mouse leukemia cells by thiols and disulfides in vitro.
    Journal of the National Cancer Institute, 1972, Volume: 49, Issue:2

    Topics: Animals; Cysteamine; Cysteine; Disulfides; In Vitro Techniques; Leukemia L1210; Lymphoma; Mercaptoet

1972
Studies on actively allergised cells. 3. Suppression of the allergic response with specific antibody and the effect of this treatment on plaque and rosette-forming cells.
    International archives of allergy and applied immunology, 1971, Volume: 40, Issue:2

    Topics: Allergens; Animals; Antibodies, Anti-Idiotypic; Antibody Formation; Antibody Specificity; Antibody-P

1971
Enzymic modification of chromosomal macromolecules. II. The formation of histone epsilon-N-trimethyl-L-lysine by a soluble chromatin methylase.
    Biochimica et biophysica acta, 1971, Mar-11, Volume: 232, Issue:2

    Topics: Animals; Arginine; Ascitic Fluid; Buffers; Carbon Isotopes; Cattle; Chemical Precipitation; Chromato

1971
Studies on the anti-plasma cell serum. I. Selective suppression of gamma-2 hemolysin in mice.
    International archives of allergy and applied immunology, 1971, Volume: 40, Issue:4-5

    Topics: Animals; Antibody Formation; Antigens; Ascitic Fluid; Cytotoxicity Tests, Immunologic; Erythrocytes;

1971
The disulphide bridges of Yoshida tumor glycoprotein.
    Life sciences, 1969, Apr-15, Volume: 8, Issue:8

    Topics: Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Cystine; Glycoproteins; Isoleucine; Mercaptoe

1969
The disulphide bridges and immunochemical properties of Yoshida ascites tumor and normal serum glycoprotein.
    Biochimica et biophysica acta, 1969, Jul-01, Volume: 181, Issue:2

    Topics: Alkylation; Animals; Antigen-Antibody Reactions; Antigens; Benzoates; Binding Sites; Chemical Phenom

1969