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mercaptoethanol and Cystic Fibrosis

mercaptoethanol has been researched along with Cystic Fibrosis in 4 studies

Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heaf, DP1
Webb, GJ1
Matthew, DJ2
Weller, PH1
Ingram, D1
Preece, MA1
Grasemann, H1
Gaston, B1
Fang, K1
Paul, K1
Ratjen, F1
Corradi, M1
Montuschi, P1
Donnelly, LE1
Pesci, A1
Kharitonov, SA1
Barnes, PJ1

Trials

2 trials available for mercaptoethanol and Cystic Fibrosis

ArticleYear
Controlled trial of intermittent aerosol therapy with sodium 2-mercaptoethane sulphonate in cystic fibrosis.
    Thorax, 1980, Volume: 35, Issue:1

    Topics: Adolescent; Aerosols; Child; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Female;

1980
Increased nitrosothiols in exhaled breath condensate in inflammatory airway diseases.
    American journal of respiratory and critical care medicine, 2001, Volume: 163, Issue:4

    Topics: Adult; Aged; Asthma; Biomarkers; Breath Tests; Cystic Fibrosis; Female; Humans; Inflammation; Lung D

2001

Other Studies

2 other studies available for mercaptoethanol and Cystic Fibrosis

ArticleYear
In vitro assessment of combined antibiotic and mucolytic treatment for Pseudomonas aeruginosa infection in cystic fibrosis.
    Archives of disease in childhood, 1983, Volume: 58, Issue:10

    Topics: Azlocillin; Cystic Fibrosis; Drug Therapy, Combination; Humans; Mercaptoethanol; Mesna; Penicillins;

1983
Decreased levels of nitrosothiols in the lower airways of patients with cystic fibrosis and normal pulmonary function.
    The Journal of pediatrics, 1999, Volume: 135, Issue:6

    Topics: Adolescent; Bronchi; Bronchoalveolar Lavage Fluid; Child; Cystic Fibrosis; Humans; Mercaptoethanol;

1999