mercaptoethanol has been researched along with Carcinoma, Anaplastic in 12 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ifosfamide (isophosphamide) and mesna (2-mercaptoethane sodium sulfonate) were administered intravenously at monthly intervals to 46 patients with advanced epithelial ovarian carcinoma refractory to or recurrent after cisplatin-containing combination chemotherapy." | 9.06 | Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study. ( Berman, ML; Blessing, JA; Homesley, HD; Malfetano, J; Sutton, GP, 1989) |
| "Ifosfamide (isophosphamide) and mesna (2-mercaptoethane sodium sulfonate) were administered intravenously at monthly intervals to 46 patients with advanced epithelial ovarian carcinoma refractory to or recurrent after cisplatin-containing combination chemotherapy." | 5.06 | Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study. ( Berman, ML; Blessing, JA; Homesley, HD; Malfetano, J; Sutton, GP, 1989) |
| "Survival and growth in in vitro cultivation of lymphocytes, lymphoma cells and some other cells including human carcinomas are profoundly improved by 2-mercaptoethanol." | 3.68 | [Use of 2-mercaptoethanol in cell culture]. ( Bannai, S, 1992) |
| "Ifosfamide/mesna has activity in a wide range of gynecologic malignancies." | 1.28 | Early phase II Gynecologic Oncology Group experience with ifosfamide/mesna in gynecologic malignancies. ( Berman, ML; Blessing, JA; Homesley, HD; Photopulos, G; Sutton, GP, 1990) |
| "A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion." | 1.28 | Severe renal failure following high-dose ifosfamide and mesna. ( de Jong, PE; Elema, JD; Mulder, NH; Willemse, PH, 1989) |
| "Ifosfamide/mesna has activity in a wide range of gynecologic malignancies." | 1.28 | Phase II experience with ifosfamide/mesna in gynecologic malignancies: preliminary report of Gynecologic Oncology Group studies. ( Berman, ML; Blessing, JA; Homesley, HD; Photopulos, G; Sutton, GP, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SCAIFE, JF | 1 |
| PERKINS, JP | 1 |
| BERTINO, JR | 1 |
| Bannai, S | 1 |
| Sutton, GP | 3 |
| Blessing, JA | 3 |
| Photopulos, G | 2 |
| Berman, ML | 3 |
| Homesley, HD | 3 |
| Willemse, PH | 1 |
| de Jong, PE | 1 |
| Elema, JD | 1 |
| Mulder, NH | 1 |
| Malfetano, J | 1 |
| Monahan, JJ | 1 |
| Hall, RH | 1 |
| Géder, L | 1 |
| Váczi, L | 1 |
| Lehel, F | 1 |
| Gönczöl, E | 1 |
| Jeney, E | 1 |
| Leibowitz, J | 1 |
| Horwitz, MS | 1 |
| Beaud, G | 1 |
| Kirn, A | 1 |
| Gros, F | 1 |
| Black, JA | 1 |
| Chan, GF | 1 |
| Hew, CL | 1 |
| Dixon, GH | 1 |
1 trial available for mercaptoethanol and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study.
Topics: Carcinoma; Drug Evaluation; Female; Humans; Ifosfamide; Leukocyte Count; Mercaptoethanol; Mesna; Mul | 1989 |
11 other studies available for mercaptoethanol and Carcinoma, Anaplastic
| Article | Year |
|---|---|
THE EHRLICH ASCITES CARCINOMA AS A TOOL FOR THE RAPID EVALUATION OF THE EFFICACY OF RADIOPROTECTIVE COMPOUNDS AT THE CELLULAR LEVEL.
Topics: Animals; Ascites; beta-Aminoethyl Isothiourea; Biological Assay; Carcinoma; Carcinoma, Ehrlich Tumor | 1964 |
INTERACTION OF ORGANIC MERCURIAL COMPOUNDS WITH DIHYDROFOLATE REDUCTASE FROM EHRLICH ASCITES CARCINOMA CELLS.
Topics: Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Chromatography | 1965 |
[Use of 2-mercaptoethanol in cell culture].
Topics: Animals; Carcinoma; Cell Division; Cell Survival; Cells, Cultured; Cystine; Humans; Lymphocytes; Lym | 1992 |
Early phase II Gynecologic Oncology Group experience with ifosfamide/mesna in gynecologic malignancies.
Topics: Antineoplastic Agents; Carcinoma; Drug Evaluation; Female; Humans; Ifosfamide; Mercaptoethanol; Mesn | 1990 |
Severe renal failure following high-dose ifosfamide and mesna.
Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma; Dose-Respons | 1989 |
Phase II experience with ifosfamide/mesna in gynecologic malignancies: preliminary report of Gynecologic Oncology Group studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Carcinoma, Squamous Cell; Ci | 1989 |
Fractionation of chromatin components.
Topics: Carbon Isotopes; Carcinoma; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Chromatin; Ch | 1973 |
Immunofluorescent studies on the reactivity of "early" and "late" herpes-immune rabbit sera with virus-induced antigenic formations of HEp-2 cells.
Topics: Amnion; Animals; Antibody Formation; Antigen-Antibody Reactions; Carcinoma; Cell Line; Culture Techn | 1970 |
Synthesis and assembly of adenovirus type 2 polypeptides. II. Reversible inhibition of hexon assembly at 42 degrees.
Topics: Adenoviridae; Amino Acids; Carbon Radioisotopes; Carcinoma; Cell Fractionation; Cell Line; Cyanides; | 1974 |
In vitro protein synthesis directed by RNA transcribed from vaccinia DNA.
Topics: Acetates; Animals; Carbon Isotopes; Carcinoma; Carcinoma, Krebs 2; Cell-Free System; DNA, Viral; Hum | 1972 |
Gene action in the human haptoglobins. 3. Isolation of the alpha-chains as single gene products. Isolation, molecular weight, and amino acid composition of alpha and beta chains.
Topics: Acetamides; Alkylation; Amino Acids; Anhydrides; Ascitic Fluid; Carcinoma; Chemical Phenomena; Chemi | 1970 |