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mercaptoethanol and Cancer of Ovary

mercaptoethanol has been researched along with Cancer of Ovary in 11 studies

Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.

Research Excerpts

ExcerptRelevanceReference
"Ifosfamide (isophosphamide) and mesna (2-mercaptoethane sodium sulfonate) were administered intravenously at monthly intervals to 46 patients with advanced epithelial ovarian carcinoma refractory to or recurrent after cisplatin-containing combination chemotherapy."9.06Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study. ( Berman, ML; Blessing, JA; Homesley, HD; Malfetano, J; Sutton, GP, 1989)
"Ifosfamide (isophosphamide) and mesna (2-mercaptoethane sodium sulfonate) were administered intravenously at monthly intervals to 46 patients with advanced epithelial ovarian carcinoma refractory to or recurrent after cisplatin-containing combination chemotherapy."5.06Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study. ( Berman, ML; Blessing, JA; Homesley, HD; Malfetano, J; Sutton, GP, 1989)
"Ifosfamide/mesna has activity in a wide range of gynecologic malignancies."1.28Early phase II Gynecologic Oncology Group experience with ifosfamide/mesna in gynecologic malignancies. ( Berman, ML; Blessing, JA; Homesley, HD; Photopulos, G; Sutton, GP, 1990)
"A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion."1.28Severe renal failure following high-dose ifosfamide and mesna. ( de Jong, PE; Elema, JD; Mulder, NH; Willemse, PH, 1989)
"Ifosfamide/mesna has activity in a wide range of gynecologic malignancies."1.28Phase II experience with ifosfamide/mesna in gynecologic malignancies: preliminary report of Gynecologic Oncology Group studies. ( Berman, ML; Blessing, JA; Homesley, HD; Photopulos, G; Sutton, GP, 1989)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Yan, F1
Ha, JH1
Yan, Y1
Ton, SB1
Wang, C1
Mutembei, B1
Alhajeri, ZA1
McNiel, AF1
Keddissi, AJ1
Zhang, Q1
Jayaraman, M1
Dhanasekaran, DN1
Tang, Q1
D'Hollander, A1
Jans, H1
Velde, GV1
Verstraete, C1
Massa, S1
Devoogdt, N1
Stakenborg, T1
Muyldermans, S1
Lagae, L1
Himmelreich, U1
Burkert, H1
Schnitker, J1
Fichtner, E1
Willemse, PH2
vd Burg, ME1
vd Gaast, A1
Neijt, JP1
ten Bokkel Huinink, WW1
Aalders, JG1
de Vries, EG1
Sutton, GP3
Blessing, JA3
Photopulos, G2
Berman, ML3
Homesley, HD3
de Jong, PE1
Elema, JD1
Mulder, NH1
Malfetano, J1
Li, GC1
Brock, N1
Li, JQ1
Guan, ZZ1
He, YJ1
Fuller, GM1
Rasco, MA1
McCombs, ML1
Barnett, DR1
Bowman, BH1
Black, JA1
Chan, GF1
Hew, CL1
Dixon, GH1

Trials

1 trial available for mercaptoethanol and Cancer of Ovary

ArticleYear
Phase II trial of ifosfamide and mesna in advanced ovarian carcinoma: a Gynecologic Oncology Group Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:11

    Topics: Carcinoma; Drug Evaluation; Female; Humans; Ifosfamide; Leukocyte Count; Mercaptoethanol; Mesna; Mul

1989

Other Studies

10 other studies available for mercaptoethanol and Cancer of Ovary

ArticleYear
Optical Coherence Tomography of Tumor Spheroids Identifies Candidates for Drug Repurposing in Ovarian Cancer.
    IEEE transactions on bio-medical engineering, 2023, Volume: 70, Issue:6

    Topics: Drug Repositioning; Female; Humans; Mercaptoethanol; Ovarian Neoplasms; Tomography, Optical Coherenc

2023
Limiting the protein corona: A successful strategy for in vivo active targeting of anti-HER2 nanobody-functionalized nanostars.
    Biomaterials, 2017, Volume: 123

    Topics: Animals; Cell Line, Tumor; CHO Cells; Cricetulus; Drug Delivery Systems; Female; Gold; Humans; Merca

2017
[Prevention of urinary tract toxicity of oxazaphosphorines by a "uroprotector". Report on a field study (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1979, Jun-01, Volume: 121, Issue:22

    Topics: Adolescent; Adult; Aged; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Gastrointestinal Dise

1979
Ifosfamide given as a 24-h infusion with mesna in patients with recurrent ovarian cancer: preliminary results.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Ifosfamide; Infusions, Intravenous;

1990
Early phase II Gynecologic Oncology Group experience with ifosfamide/mesna in gynecologic malignancies.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26 Suppl

    Topics: Antineoplastic Agents; Carcinoma; Drug Evaluation; Female; Humans; Ifosfamide; Mercaptoethanol; Mesn

1990
Severe renal failure following high-dose ifosfamide and mesna.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:5

    Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma; Dose-Respons

1989
Phase II experience with ifosfamide/mesna in gynecologic malignancies: preliminary report of Gynecologic Oncology Group studies.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Carcinoma, Squamous Cell; Ci

1989
Ifosfamide and Mesna in advanced malignancies.
    Chinese medical journal, 1988, Volume: 101, Issue:3

    Topics: Adult; Aged; Carcinoma, Bronchogenic; Female; Hematuria; Humans; Ifosfamide; Lung Neoplasms; Lymphom

1988
Subunit composition of haptoglobin 2-2 polymers.
    Biochemistry, 1973, Jan-16, Volume: 12, Issue:2

    Topics: Amino Acids; Ascitic Fluid; Disulfides; Electrophoresis, Polyacrylamide Gel; Female; Haptoglobins; H

1973
Gene action in the human haptoglobins. 3. Isolation of the alpha-chains as single gene products. Isolation, molecular weight, and amino acid composition of alpha and beta chains.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:1

    Topics: Acetamides; Alkylation; Amino Acids; Anhydrides; Ascitic Fluid; Carcinoma; Chemical Phenomena; Chemi

1970
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