mercaptoethanol has been researched along with Bladder Diseases in 7 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Excerpt | Relevance | Reference |
---|---|---|
"MESNA is shown to enhance excretion of cysteine in urine." | 1.27 | Excretion of sodium 2-mercaptoethanesulphonate (MESNA) in the urine of volunteers after oral dosing. ( Jones, MS; Murrell, RD; Shaw, IC, 1985) |
"Thirty-two patients with advanced cancer were treated in a phase I-II trial with ifosfamide plus mesnum." | 1.26 | Mesnum as a protector against kidney and bladder toxicity with high-dose ifosfamide treatment. ( Falkson, G; Falkson, HC; Stapelberg, R; Van Dyk, JJ, 1982) |
"Mesna is a pharmacologically unremarkable, physiologically largely inert and almost totally non-toxic thio compound." | 1.26 | Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna). ( Brock, N; Pohl, J; Scheef, W; Stekar, J, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Araujo, CE | 1 |
Tessler, J | 1 |
Kunze, E | 1 |
Köhnecke, B | 1 |
Engelhardt, W | 1 |
Brock, N | 2 |
Pohl, J | 2 |
Freedman, A | 1 |
Ehrlich, RM | 1 |
Ljung, BM | 1 |
Falkson, G | 1 |
Van Dyk, JJ | 1 |
Stapelberg, R | 1 |
Falkson, HC | 1 |
Stekar, J | 1 |
Scheef, W | 1 |
Jones, MS | 1 |
Murrell, RD | 1 |
Shaw, IC | 1 |
Clark, H | 1 |
Ronald, AR | 1 |
Turck, M | 1 |
1 trial available for mercaptoethanol and Bladder Diseases
Article | Year |
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Treatment of ifosfamide-induced urothelial toxicity by oral administration of sodium 2-mercaptoethane sulphonate (MESNA) to patients with inoperable lung cancer.
Topics: Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combina | 1983 |
6 other studies available for mercaptoethanol and Bladder Diseases
Article | Year |
---|---|
[Autoradiographic studies on the protective effect of mesna in the urinary bladder mucosa of the rat during administration of cyclophosphamide (preliminary communication)].
Topics: Animals; Autoradiography; Cyclophosphamide; Female; Mercaptoethanol; Mesna; Mucous Membrane; Rats; R | 1983 |
Prevention of cyclophosphamide cystitis with 2-mercaptoethane sodium sulfonate: a histologic study.
Topics: Animals; Cyclophosphamide; Cystitis; Drug Evaluation, Preclinical; Edema; Male; Mercaptoethanol; Mes | 1984 |
Mesnum as a protector against kidney and bladder toxicity with high-dose ifosfamide treatment.
Topics: Adult; Aged; Cyclophosphamide; Female; Humans; Ifosfamide; Kidney Diseases; Leukopenia; Male; Mercap | 1982 |
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna).
Topics: Animals; Cyclophosphamide; Dogs; Drug Interactions; Female; Ifosfamide; Kinetics; Lethal Dose 50; Ma | 1982 |
Excretion of sodium 2-mercaptoethanesulphonate (MESNA) in the urine of volunteers after oral dosing.
Topics: Administration, Oral; Adult; Cysteine; Disulfides; Humans; Male; Mercaptoethanol; Mesna; Sulfhydryl | 1985 |
Serum antibody response in renal versus bladder bacteriuria.
Topics: Antibodies; Bacteriuria; Escherichia coli Infections; Female; Hemagglutination Tests; Humans; Kidney | 1971 |