mercaptoethanol has been researched along with Bladder Diseases in 7 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "MESNA is shown to enhance excretion of cysteine in urine." | 1.27 | Excretion of sodium 2-mercaptoethanesulphonate (MESNA) in the urine of volunteers after oral dosing. ( Jones, MS; Murrell, RD; Shaw, IC, 1985) |
| "Thirty-two patients with advanced cancer were treated in a phase I-II trial with ifosfamide plus mesnum." | 1.26 | Mesnum as a protector against kidney and bladder toxicity with high-dose ifosfamide treatment. ( Falkson, G; Falkson, HC; Stapelberg, R; Van Dyk, JJ, 1982) |
| "Mesna is a pharmacologically unremarkable, physiologically largely inert and almost totally non-toxic thio compound." | 1.26 | Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna). ( Brock, N; Pohl, J; Scheef, W; Stekar, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Araujo, CE | 1 |
| Tessler, J | 1 |
| Kunze, E | 1 |
| Köhnecke, B | 1 |
| Engelhardt, W | 1 |
| Brock, N | 2 |
| Pohl, J | 2 |
| Freedman, A | 1 |
| Ehrlich, RM | 1 |
| Ljung, BM | 1 |
| Falkson, G | 1 |
| Van Dyk, JJ | 1 |
| Stapelberg, R | 1 |
| Falkson, HC | 1 |
| Stekar, J | 1 |
| Scheef, W | 1 |
| Jones, MS | 1 |
| Murrell, RD | 1 |
| Shaw, IC | 1 |
| Clark, H | 1 |
| Ronald, AR | 1 |
| Turck, M | 1 |
1 trial available for mercaptoethanol and Bladder Diseases
| Article | Year |
|---|---|
Treatment of ifosfamide-induced urothelial toxicity by oral administration of sodium 2-mercaptoethane sulphonate (MESNA) to patients with inoperable lung cancer.
Topics: Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combina | 1983 |
6 other studies available for mercaptoethanol and Bladder Diseases
| Article | Year |
|---|---|
[Autoradiographic studies on the protective effect of mesna in the urinary bladder mucosa of the rat during administration of cyclophosphamide (preliminary communication)].
Topics: Animals; Autoradiography; Cyclophosphamide; Female; Mercaptoethanol; Mesna; Mucous Membrane; Rats; R | 1983 |
Prevention of cyclophosphamide cystitis with 2-mercaptoethane sodium sulfonate: a histologic study.
Topics: Animals; Cyclophosphamide; Cystitis; Drug Evaluation, Preclinical; Edema; Male; Mercaptoethanol; Mes | 1984 |
Mesnum as a protector against kidney and bladder toxicity with high-dose ifosfamide treatment.
Topics: Adult; Aged; Cyclophosphamide; Female; Humans; Ifosfamide; Kidney Diseases; Leukopenia; Male; Mercap | 1982 |
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna).
Topics: Animals; Cyclophosphamide; Dogs; Drug Interactions; Female; Ifosfamide; Kinetics; Lethal Dose 50; Ma | 1982 |
Excretion of sodium 2-mercaptoethanesulphonate (MESNA) in the urine of volunteers after oral dosing.
Topics: Administration, Oral; Adult; Cysteine; Disulfides; Humans; Male; Mercaptoethanol; Mesna; Sulfhydryl | 1985 |
Serum antibody response in renal versus bladder bacteriuria.
Topics: Antibodies; Bacteriuria; Escherichia coli Infections; Female; Hemagglutination Tests; Humans; Kidney | 1971 |