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mercaptoethanol and Bladder Diseases

mercaptoethanol has been researched along with Bladder Diseases in 7 studies

Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.

Research Excerpts

ExcerptRelevanceReference
"MESNA is shown to enhance excretion of cysteine in urine."1.27Excretion of sodium 2-mercaptoethanesulphonate (MESNA) in the urine of volunteers after oral dosing. ( Jones, MS; Murrell, RD; Shaw, IC, 1985)
"Thirty-two patients with advanced cancer were treated in a phase I-II trial with ifosfamide plus mesnum."1.26Mesnum as a protector against kidney and bladder toxicity with high-dose ifosfamide treatment. ( Falkson, G; Falkson, HC; Stapelberg, R; Van Dyk, JJ, 1982)
"Mesna is a pharmacologically unremarkable, physiologically largely inert and almost totally non-toxic thio compound."1.26Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna). ( Brock, N; Pohl, J; Scheef, W; Stekar, J, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Araujo, CE1
Tessler, J1
Kunze, E1
Köhnecke, B1
Engelhardt, W1
Brock, N2
Pohl, J2
Freedman, A1
Ehrlich, RM1
Ljung, BM1
Falkson, G1
Van Dyk, JJ1
Stapelberg, R1
Falkson, HC1
Stekar, J1
Scheef, W1
Jones, MS1
Murrell, RD1
Shaw, IC1
Clark, H1
Ronald, AR1
Turck, M1

Trials

1 trial available for mercaptoethanol and Bladder Diseases

ArticleYear
Treatment of ifosfamide-induced urothelial toxicity by oral administration of sodium 2-mercaptoethane sulphonate (MESNA) to patients with inoperable lung cancer.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:2

    Topics: Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combina

1983

Other Studies

6 other studies available for mercaptoethanol and Bladder Diseases

ArticleYear
[Autoradiographic studies on the protective effect of mesna in the urinary bladder mucosa of the rat during administration of cyclophosphamide (preliminary communication)].
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:6

    Topics: Animals; Autoradiography; Cyclophosphamide; Female; Mercaptoethanol; Mesna; Mucous Membrane; Rats; R

1983
Prevention of cyclophosphamide cystitis with 2-mercaptoethane sodium sulfonate: a histologic study.
    The Journal of urology, 1984, Volume: 132, Issue:3

    Topics: Animals; Cyclophosphamide; Cystitis; Drug Evaluation, Preclinical; Edema; Male; Mercaptoethanol; Mes

1984
Mesnum as a protector against kidney and bladder toxicity with high-dose ifosfamide treatment.
    Cancer chemotherapy and pharmacology, 1982, Volume: 9, Issue:2

    Topics: Adult; Aged; Cyclophosphamide; Female; Humans; Ifosfamide; Kidney Diseases; Leukopenia; Male; Mercap

1982
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna).
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:12

    Topics: Animals; Cyclophosphamide; Dogs; Drug Interactions; Female; Ifosfamide; Kinetics; Lethal Dose 50; Ma

1982
Excretion of sodium 2-mercaptoethanesulphonate (MESNA) in the urine of volunteers after oral dosing.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:5

    Topics: Administration, Oral; Adult; Cysteine; Disulfides; Humans; Male; Mercaptoethanol; Mesna; Sulfhydryl

1985
Serum antibody response in renal versus bladder bacteriuria.
    The Journal of infectious diseases, 1971, Volume: 123, Issue:5

    Topics: Antibodies; Bacteriuria; Escherichia coli Infections; Female; Hemagglutination Tests; Humans; Kidney

1971