mercaptoethanol has been researched along with Arteriosclerosis in 3 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In-vitro studies have demonstrated that homocysteine decreases the production or bioavailability of vasodilator autacoids, such as prostacyclin and NO." | 1.30 | Homocysteine decreases endothelin-1 production by cultured human endothelial cells. ( Atger, V; Benoit, MO; Borderie, D; Demuth, K; Lotersztajn, S; Moatti, N; Sauvaget, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loscalzo, J | 1 |
| Demuth, K | 1 |
| Atger, V | 1 |
| Borderie, D | 1 |
| Benoit, MO | 1 |
| Sauvaget, D | 1 |
| Lotersztajn, S | 1 |
| Moatti, N | 1 |
| May, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| High Dose Intravenous Versus Low Dose Oral Vitamin C in Burn Care: Potential Protective Effects in the Severely Burned: A Retrospective Cohort Study[NCT05612867] | 54 participants (Actual) | Observational | 2020-12-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mercaptoethanol and Arteriosclerosis
| Article | Year |
|---|---|
Endothelial injury, vasoconstriction, and its prevention.
Topics: Animals; Arteriosclerosis; Endothelium, Vascular; Humans; Mercaptoethanol; Muscle, Smooth, Vascular; | 1995 |
How does ascorbic acid prevent endothelial dysfunction?
Topics: Animals; Antioxidants; Arteriosclerosis; Ascorbic Acid; Coronary Vessels; Endothelium, Vascular; Enz | 2000 |
1 other study available for mercaptoethanol and Arteriosclerosis
| Article | Year |
|---|---|
Homocysteine decreases endothelin-1 production by cultured human endothelial cells.
Topics: Arteriosclerosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Endothelin-1; Endothel | 1999 |