mercaptoethanol has been researched along with Alzheimer Disease in 5 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seladin-1 (SELective Alzheimer's Disease INdicator-1) is an anti-apoptotic gene, which is down-regulated in brain regions affected by Alzheimer's disease (AD)." | 1.33 | Neuronal differentiation of human mesenchymal stem cells: changes in the expression of the Alzheimer's disease-related gene seladin-1. ( Benvenuti, S; Cellai, I; Danza, G; Deledda, C; Francini, F; Gelmini, S; Greeve, I; Luciani, P; Maggi, R; Peri, A; Rosati, F; Rossi, M; Saccardi, R; Serio, M; Squecco, R; Urbani, S, 2006) |
| "Patients with solid tumors showed the largest and patients with hematologic malignancies the smallest percentage increase in CK-BB after reactivation." | 1.27 | Reactivation of serum creatine kinase isoenzyme BB in patients with malignancies. ( Abbott, LB; Lott, JA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benvenuti, S | 1 |
| Saccardi, R | 1 |
| Luciani, P | 1 |
| Urbani, S | 1 |
| Deledda, C | 1 |
| Cellai, I | 1 |
| Francini, F | 1 |
| Squecco, R | 1 |
| Rosati, F | 1 |
| Danza, G | 1 |
| Gelmini, S | 1 |
| Greeve, I | 1 |
| Rossi, M | 1 |
| Maggi, R | 1 |
| Serio, M | 1 |
| Peri, A | 1 |
| Abbott, LB | 1 |
| Lott, JA | 1 |
| Frey, WH | 1 |
| Emory, CR | 1 |
| Wiebenga, ME | 1 |
| Saxena, S | 1 |
| Cardelli, D | 1 |
| Ala, TA | 1 |
| Tollefson, GD | 1 |
| Campbell, E | 1 |
| Pearson, RC | 1 |
| Parkinson, D | 1 |
| Iqbal, K | 1 |
| Grundke-Iqbal, I | 1 |
| Zaidi, T | 1 |
| Ali, N | 1 |
| Wisniewski, HM | 1 |
5 other studies available for mercaptoethanol and Alzheimer Disease
| Article | Year |
|---|---|
Neuronal differentiation of human mesenchymal stem cells: changes in the expression of the Alzheimer's disease-related gene seladin-1.
Topics: Alzheimer Disease; Biomarkers; Calcium; Cell Adhesion Molecules; Cell Differentiation; Cells, Cultur | 2006 |
Reactivation of serum creatine kinase isoenzyme BB in patients with malignancies.
Topics: Adenylate Kinase; Alzheimer Disease; Blood Protein Electrophoresis; Chelating Agents; Creatine Kinas | 1984 |
Inhibitor of antagonist binding to the muscarinic receptor is elevated in Alzheimer's brain.
Topics: Aged; Alkaline Phosphatase; Alzheimer Disease; Brain Chemistry; Female; Humans; Kinetics; Male; Merc | 1994 |
Methods to uncover an antibody epitope in the KPI domain of Alzheimer's amyloid precursor protein for immunohistochemistry in human brain.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Antibodies; Blotting, Wester | 1999 |
Are Alzheimer neurofibrillary tangles insoluble polymers?
Topics: Alzheimer Disease; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Humans; Intermediate Filaments | 1986 |