mercaptoethanol has been researched along with Abnormalities, Autosome in 12 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In routine diagnostics of hematologic malignancies isolation of high-quality RNA is a prerequisite." | 5.39 | Addition of β-mercaptoethanol is a prerequisite for high-quality RNA isolation using QIAsymphony technology as demonstrated by detection of molecular aberrations in hematologic malignancies. ( Chu, IW; Geertsma-Kleinekoort, WM; Goudswaard, CS; Hogenbirk-Hupkes, PE; Valk, PJ; van de Werf, M; van der Poel-van de Luytgaarde, SC; van Hoven-Beijen, MA; van Kapel, J, 2013) |
| "Peripheral blood lymphocytes from eight Fanconi anemia (FA) patients, 14 FA heterozygotes, and nine normal subjects have been tested for their susceptibility to chromosomal breakage induction by diepoxybutane (DEB) and by two peroxides." | 3.67 | Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes. ( Alimena, G; Dallapiccola, B; Gandini, E; Isacchi, G; Mokini, V; Porfirio, B, 1985) |
| "In routine diagnostics of hematologic malignancies isolation of high-quality RNA is a prerequisite." | 1.39 | Addition of β-mercaptoethanol is a prerequisite for high-quality RNA isolation using QIAsymphony technology as demonstrated by detection of molecular aberrations in hematologic malignancies. ( Chu, IW; Geertsma-Kleinekoort, WM; Goudswaard, CS; Hogenbirk-Hupkes, PE; Valk, PJ; van de Werf, M; van der Poel-van de Luytgaarde, SC; van Hoven-Beijen, MA; van Kapel, J, 2013) |
| "SCEs and chromosome aberrations differed considerably in their induction kinetics in lymphocytes exposed to PAM, and these disparities suggested an uncoupling of the two phenomena." | 1.27 | Attenuation of cytogenetic damage by 2-mercaptoethanesulfonate in cultured human lymphocytes exposed to cyclophosphamide and its reactive metabolites. ( Erexson, GL; Kligerman, AD; Wilmer, JL, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van der Poel-van de Luytgaarde, SC | 1 |
| Geertsma-Kleinekoort, WM | 1 |
| Goudswaard, CS | 1 |
| Hogenbirk-Hupkes, PE | 1 |
| van Hoven-Beijen, MA | 1 |
| van de Werf, M | 1 |
| Chu, IW | 1 |
| van Kapel, J | 1 |
| Valk, PJ | 1 |
| Becher, R | 1 |
| Kakati, S | 1 |
| Gibas, Z | 1 |
| Sandberg, AA | 1 |
| Porfirio, B | 2 |
| Dallapiccola, B | 2 |
| Mokini, V | 2 |
| Alimena, G | 2 |
| Isacchi, G | 2 |
| Mandelli, F | 1 |
| Gandini, E | 2 |
| Sasaki, MS | 1 |
| Albrecht, AM | 1 |
| Biedler, JL | 1 |
| Hutchison, DJ | 1 |
| Spengler, BA | 1 |
| Stockert, E | 1 |
| Brogger, A | 1 |
| Wilmer, JL | 1 |
| Erexson, GL | 1 |
| Kligerman, AD | 1 |
| Cowell, JK | 1 |
| Rutland, P | 1 |
| Jay, M | 1 |
| Hungerford, J | 1 |
| Dzenis, IG | 1 |
| Ranu, RS | 1 |
| Kaji, A | 1 |
| Satô, S | 1 |
12 other studies available for mercaptoethanol and Abnormalities, Autosome
| Article | Year |
|---|---|
Addition of β-mercaptoethanol is a prerequisite for high-quality RNA isolation using QIAsymphony technology as demonstrated by detection of molecular aberrations in hematologic malignancies.
Topics: Chromosome Aberrations; Fusion Proteins, bcr-abl; Hematologic Neoplasms; Humans; Hydroxymethylbilane | 2013 |
Cytogenetic testing of mutagenic and radioprotective effects of mesna.
Topics: Chromosome Aberrations; Crossing Over, Genetic; Drug Evaluation, Preclinical; Gamma Rays; Humans; In | 1983 |
[Effects of oxidants and antioxidants on chromosome breaks in Fanconi's anemia].
Topics: Anemia, Aplastic; Antioxidants; Ascorbic Acid; Chromosome Aberrations; Cysteine; Epoxy Compounds; Et | 1983 |
Sister chromatid exchange and chromatid interchange as possible manifestation of different DNA repair processes.
Topics: Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; Crossing Over, Genetic; Cycloheximide | 1977 |
Radiation-induced murine leukemia ERLD in cell culture.
Topics: Animals; Antigens, Neoplasm; Asparagine; Cell Line; Chromosome Aberrations; Culture Media; Glutamine | 1976 |
Is the chromatid gap a folding defect due to protein change? Evidence from mercaptoethanol treatment of human lymphocyte chromosomes.
Topics: Adult; Cell Division; Chromatids; Chromosome Aberrations; Humans; Lymphocytes; Male; Mercaptoethanol | 1975 |
Attenuation of cytogenetic damage by 2-mercaptoethanesulfonate in cultured human lymphocytes exposed to cyclophosphamide and its reactive metabolites.
Topics: Acrolein; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Cyclophosphamide; Dose-Response Relat | 1986 |
Effect of the esterase-D phenotype on its in vitro enzyme activity.
Topics: Alleles; Carboxylesterase; Carboxylic Ester Hydrolases; Chromosome Aberrations; Chromosome Deletion; | 1986 |
Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes.
Topics: Anemia, Aplastic; Antioxidants; Ascorbic Acid; Cells, Cultured; Chromosome Aberrations; Cross-Linkin | 1985 |
Longitudinal differentiation of human mitotic chromosomes. Communication II. Analysis of pericentric inversion of the first chromosome in a child with anomalous sex differentiation.
Topics: Child; Chromatin; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human, 1-3; Female; Hum | 1974 |
Evidence for specific inhibition of translocation of aminoacyl-transfer ribonucleic acid by the pretreatment of ribosomes of Bacillus subtilis with p-chloromercuribenzoate.
Topics: Bacillus subtilis; Binding Sites; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradien | 1972 |
Electron microscopy on mitotic and chromosomal aberrations induced by cholchicine, mercaptoethanol and nitrogen mustard.
Topics: Chromosome Aberrations; Colchicine; Mercaptoethanol; Microscopy, Electron; Mitosis; Nitrogen Mustard | 1970 |