merbarone and Sarcoma

merbarone has been researched along with Sarcoma* in 1 studies

Trials

1 trial(s) available for merbarone and Sarcoma

Article	Year
Phase II trial of merbarone in soft tissue sarcoma. A Southwest Oncology Group study. Investigational new drugs, 1992, Volume: 10, Issue:4 Thirty-seven patients with advanced soft tissue sarcoma were treated with merbarone utilizing a daily intravenous schedule for five days. Only one partial response was observed in the thirty-three evaluable patients. The major toxicities were renal, with elevation of creatinine and/or proteinuria, and gastrointestinal, with mild to moderate nausea and vomiting. Merbarone in this dose and schedule has minimal activity in soft tissue sarcoma. Topics: Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Thiobarbiturates	1992

Article

Year

Phase II trial of merbarone in soft tissue sarcoma. A Southwest Oncology Group study.

Investigational new drugs, 1992, Volume: 10, Issue:4

Thirty-seven patients with advanced soft tissue sarcoma were treated with merbarone utilizing a daily intravenous schedule for five days. Only one partial response was observed in the thirty-three evaluable patients. The major toxicities were renal, with elevation of creatinine and/or proteinuria, and gastrointestinal, with mild to moderate nausea and vomiting. Merbarone in this dose and schedule has minimal activity in soft tissue sarcoma.

Topics: Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Thiobarbiturates

1992