meprobamate has been researched along with Porphyrias in 5 studies
Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The porphyrias are a metabolic disorders of heme biosynthesis characterized by the excessive production and excretion of porphyrins and porphyrin precursors." | 2.39 | [Porphyrias and drugs]. ( Karasawa, M; Murakami, H; Tamura, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| COWGER, ML | 1 |
| LABBE, RF | 1 |
| Murakami, H | 1 |
| Tamura, J | 1 |
| Karasawa, M | 1 |
| Doss, M | 1 |
| Sixel-Dietrich, F | 1 |
| Verspohl, F | 1 |
| Racz, WJ | 1 |
| Marks, GS | 1 |
| Cripps, DJ | 1 |
| Peters, HA | 1 |
1 review available for meprobamate and Porphyrias
| Article | Year |
|---|---|
[Porphyrias and drugs].
Topics: Carbamazepine; Contraindications; Estrogens; Hemin; Humans; Hypnotics and Sedatives; Meprobamate; Po | 1995 |
4 other studies available for meprobamate and Porphyrias
| Article | Year |
|---|---|
CONTRAINDICATIONS OF BIOLOGICAL-OXIDATION INHIBITORS IN THE TREATMENT OF PORPHYRIA.
Topics: Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antifungal Agents; Antipyretics; Barbiturates | 1965 |
"Glucose effect" and rate limiting function of uroporphyrinogen synthase on porphyrin metabolism in hepatocyte culture: relationship with human acute hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Cells, Cultured; Chick E | 1985 |
Drug-induced porphyrin biosynthesis. II. Simple procedure for screening drugs for porphyria-inducing activity.
Topics: Animals; Anticonvulsants; Barbiturates; Benzene Derivatives; Chick Embryo; Culture Techniques; Dimet | 1969 |
Stool porphyrins in acute intermittent and hereditary coproporphyria. Adverse effect of tranquilizers.
Topics: Acute Disease; Adult; Chemical Phenomena; Chemistry; Chlorpromazine; Chromatography; Feces; Female; | 1970 |