Compounds > meprobamate
Page last updated: 2024-10-30

meprobamate and Poisoning

meprobamate has been researched along with Poisoning in 44 studies

Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
" Twenty-five patients in grade IV coma have been treated with the column for treatment of drug overdose or agricultural chemical poisoning; the clinical course of one meprobamate-poisoned patient is described in detail."3.66A hemoperfusion column based on activated carbon granules coated with an ultrathin membrane of cellulose acetate. ( Bantjes, A; Dijkhuis, IC; Feijen, J; Tijssen, J; van Dijk, B; van Doorn, AW; Vonk, CR, 1979)
"Meprobamate was implicated in 50 (6."1.26Meprobamate overdosage: a continuing problem. ( Allen, MD; Greenblatt, DJ; Noel, BJ, 1977)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199040 (90.91)18.7374
1990's2 (4.55)18.2507
2000's2 (4.55)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Høiseth, G2
Karinen, R1
Sørlid, HK1
Bramness, JG2
SHANE, AM1
HIRSCH, S1
WIESENER, H1
HARDY, W1
TENPAS, A1
NIXON, RK1
FROMMEL, E1
FLEURY, C1
LEDEBUR, IV1
BEGUIN, M1
FAMILY, S1
DYMENT, PG1
CURTIS, DD1
GOURRICH, GE1
MOLLARET, P1
POCIDALO, JJ1
Christophersen, AS1
Mørland, J1
Goulon, M3
Nouailhat, F1
Lévy-Alcover, MA1
Dordain, G1
de Groot, G1
Maes, RA1
van Heijst, AN1
Laaban, JP1
Bodenan, P1
Marty, M1
Cosson, JP1
Rochemaure, J1
Follath, F1
Nilsson, E1
Freund, LG1
Lin, JL1
Lim, PS1
van Dijk, B2
Vonk, CR2
Dijkhuis, IC2
Tijssen, J1
Bantjes, A1
van Doorn, AW1
Feijen, J1
Allen, MD1
Greenblatt, DJ1
Noel, BJ1
Bilinsky, RT1
Goulding, R2
Widdop, B1
Medd, RK1
Braithwaite, RA1
Rees, AJ1
Brandslund, I1
Bismuth, C2
Mangin, P1
Kintz, P1
Tracqui, A1
Ludes, B1
Lugnier, AA1
Chaumont, AJ1
Pichler, M1
Finkenstedt, G1
Kleinberger, G1
Kotzaurek, R1
Pall, H1
Pilgerstorfer, HW1
Raberger, G1
Szeless, S1
von Baeyer, H1
Kunst, H1
Freiberg, J1
Grosser, KD1
Sieberth, HG1
Selye, H1
Solymoss, B1
Sunshine, I1
McBay, AJ1
Gaultier, M2
Gervais, P1
Schindera, F1
Gädeke, R1
Ross, C1
Höhmann, H1
Pohl, KD1
Sauer, M1
Bischoff, W1
Irey, NS1
Froede, RC1
Lanzoni, V1
Hulting, J1
Thorstrand, C1
Afifi, AA1
Sacks, ST1
Liu, VY1
Weil, MH1
Shubin, H1
Bloomer, HA1
Maddock, RK1
Sheehe, JB1
Adams, EJ1
Riechert, M1
Barois, A1
Gajdos, P1
Labrousse, J1
Schortgen, G1
Van Amerongen, G1
Robert, JF1
Kurtz, D1
Feuerstein, J1
Weber, M1
Reeb, M1
Rohmer, F1
Mantz, JM1
Hamann, B1
Tempe, JD1
Storck, D1
Otteni, JC1
Martin, G1
Dunlop, M1
Curnow, DH1
Fournier, E1
Fréjaville, JP1
Nicaise, AM1
Jenis, EH1
Payne, RJ1
Goldbaum, LR1

Reviews

3 reviews available for meprobamate and Poisoning

ArticleYear
[PHARMACOLOGY AND TOXICOLOGY. DISEASES DUE TO EXTERNAL CAUSES].
    Monatsschrift fur Kinderheilkunde, 1963, Volume: 111

    Topics: Accidents; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Child; Drug

1963
Toxicological findings in fatal poisonings.
    Clinical chemistry, 1973, Volume: 19, Issue:4

    Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordi

1973
Drug-induced coma.
    The Surgical clinics of North America, 1968, Volume: 48, Issue:2

    Topics: Alcoholic Intoxication; Barbiturates; Coma; Glutethimide; Humans; Meprobamate; Phenothiazines; Poiso

1968

Other Studies

41 other studies available for meprobamate and Poisoning

ArticleYear
The effect of scheduling and withdrawal of carisoprodol on prevalence of intoxications with the drug.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:5

    Topics: Accidents, Traffic; Automobile Driving; Carisoprodol; Forensic Toxicology; Humans; Meprobamate; Musc

2009
Three cases of meprobamate poisoning.
    Canadian Medical Association journal, 1956, Jun-01, Volume: 74, Issue:11

    Topics: Anticonvulsants; Cardiovascular Agents; Humans; Meprobamate; Muscle Relaxants, Central; Poisoning

1956
[Polyneuritis secondary to massive meprobamate poisoning (unpublished case) with review of the literature on the complications caused by tranquilizers].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1962, Dec-08, Volume: 38

    Topics: Humans; Meprobamate; Neuritis; Poisoning; Tranquilizing Agents

1962
MEPROBAMATE INTOXICATION TREATED BY PERITONEAL DIALYSIS: REPORT OF A CASE.
    Henry Ford Hospital medical bulletin, 1963, Volume: 11

    Topics: Dialysis; Fluid Therapy; Meprobamate; Neurologic Manifestations; Peritoneal Dialysis; Peritoneum; Po

1963
THE PLACE OF ACETYLSALICYLIC ACID IN PSYCHOPHARMACOLOGY. AN EXPERIMENTAL STUDY.
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Amphetamine; Amphetamines; Animals; Aspirin; Body Temperature Regulation; Chlordiazepoxide; Chlorpro

1963
MEPROBAMATE POISONING TREATED BY PERITONEAL DIALYSIS.
    The Journal of pediatrics, 1965, Volume: 67

    Topics: Dialysis; Fluid Therapy; Humans; Infant; Meprobamate; Peritoneal Dialysis; Poisoning; Renal Dialysis

1965
HYPOVENTILATION IN PATIENTS WITH NORMAL LUNGS. MANAGEMENT OF DRUG POISONING, TETANUS, AND MYASTHENIA GRAVIS.
    Annals of the New York Academy of Sciences, 1965, Mar-24, Volume: 121

    Topics: Antidotes; Barbiturates; Cholinesterase Inhibitors; Glutethimide; Humans; Hypoventilation; Meprobama

1965
Carisoprodol intoxications: a retrospective study of forensic autopsy material from 1992-2003.
    International journal of legal medicine, 2007, Volume: 121, Issue:5

    Topics: Adolescent; Adult; Aged; Carisoprodol; Drug Prescriptions; Female; Forensic Toxicology; Humans; Male

2007
[Toxic coma with autonomic sideration, with a favorable outcome].
    Revue neurologique, 1967, Volume: 116, Issue:4

    Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam;

1967
A toxicological evaluation of hemoperfusion using pharmacokinetic principles.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Barbiturates; Drug Combinations; Evaluation Studies as Topic; Hemoperfusion; Humans; Hydroxyzine; Ma

1980
Esophageal spasm in a case of drug overdose.
    The New England journal of medicine, 1984, Nov-29, Volume: 311, Issue:22

    Topics: Aged; Esophageal Diseases; Humans; Male; Meprobamate; Poisoning; Secobarbital; Spasm

1984
[Assays of serum concentrations in drug intoxications].
    Schweizerische medizinische Wochenschrift, 1982, Aug-03, Volume: 112, Issue:31-32

    Topics: Acetaminophen; Barbiturates; Humans; Meprobamate; Poisoning; Salicylates

1982
Physostigmine treatment in various drug-induced intoxications.
    Annals of clinical research, 1982, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Aged; Benzodiazepines; Consciousness; Heart; Humans; Hypnotics and Sedatives; Mep

1982
Severe meprobamate intoxication treated by hemoperfusion over amberlite resin.
    Artificial organs, 1981, Volume: 5, Issue:1

    Topics: Adult; Female; Hemoperfusion; Humans; Meprobamate; Poisoning; Resins, Plant; Time Factors

1981
Continuous arteriovenous hemoperfusion in acute poisoning.
    Blood purification, 1994, Volume: 12, Issue:2

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Coma; Fatal Outcome; Female; Hemodynamics; Hemoperfusion

1994
[Detoxification of toxic agents from the blood. Clinical results with a new hemoperfusion system: the Hemopur 260].
    Tijdschrift voor ziekenverpleging, 1979, Aug-07, Volume: 32, Issue:16

    Topics: Barbiturates; Biotransformation; Diuresis; Evaluation Studies as Topic; Extracorporeal Circulation;

1979
A hemoperfusion column based on activated carbon granules coated with an ultrathin membrane of cellulose acetate.
    Artificial organs, 1979, Volume: 3, Issue:1

    Topics: Acetates; Cellulose; Charcoal; Coma; Hemoperfusion; Humans; Membranes, Artificial; Meprobamate; Pois

1979
Meprobamate overdosage: a continuing problem.
    Clinical toxicology, 1977, Volume: 11, Issue:5

    Topics: Adolescent; Adult; Barbiturates; Benactyzine; Coma; Ethanol; Female; Humans; Hypnotics and Sedatives

1977
Resin hemoperfusion for acute drug intoxication.
    Archives of internal medicine, 1976, Volume: 136, Issue:10

    Topics: Adult; Female; Humans; Meprobamate; Poisoning; Renal Dialysis; Resins, Plant

1976
Experience with hemoperfusion in drug abuse.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Adult; Barbiturates; Charcoal; Ethchlorvynol; Female; Glutethimide; Humans; Kidneys, Artificial; Mal

1976
Experimental drug intoxication: treatment with charcoal haemoperfusion.
    Archives of toxicology, 1975, Sep-05, Volume: 34, Issue:1

    Topics: Acetaminophen; Alcoholic Intoxication; Animals; Aspirin; Barbiturates; Biocompatible Materials; Char

1975
[A case of acute carisoprodol poisoning. Symptoms and metabolism].
    Ugeskrift for laeger, 1976, Jan-26, Volume: 138, Issue:5

    Topics: Adult; Carisoprodol; Female; Humans; Meprobamate; Poisoning

1976
Biological valuation of extra-corporeal techniques in acute poisoning.
    Acta clinica Belgica. Supplementum, 1990, Volume: 13

    Topics: Hemoperfusion; Humans; Inactivation, Metabolic; Intestinal Absorption; Liver; Meprobamate; Paraquat;

1990
A fatal ingestion of sparteine and meprobamate: medicolegal and toxicological data.
    Acta medicinae legalis et socialis, 1989, Volume: 39, Issue:1

    Topics: Acute Disease; Adult; Autopsy; Chromatography, Gas; Female; Humans; Meprobamate; Poisoning; Spartein

1989
[Therapy of intoxications due to hypnotics in an intensive care unit (author's transl)].
    Wiener klinische Wochenschrift, 1973, Sep-28, Volume: 85, Issue:39

    Topics: Adrenergic alpha-Antagonists; Antidotes; Barbiturates; Bromides; Diazepam; Diuresis; Diuretics; Fema

1973
[Haemodialysis in intoxication with hypnotics (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Feb-01, Volume: 99, Issue:5

    Topics: Acute Kidney Injury; Adult; Barbiturates; Blood Pressure; Bromides; Diuresis; Diuretics; Electroence

1974
Protection by catatoxic steroids against meprobamate.
    Neuropharmacology, 1970, Volume: 9, Issue:4

    Topics: Anabolic Agents; Animals; Desoxycorticosterone; Estradiol; Ethylestrenol; Female; Meprobamate; Norst

1970
Basic toxicology.
    Pediatric clinics of North America, 1970, Volume: 17, Issue:3

    Topics: Analgesics; Anticonvulsants; Antidotes; Barbiturates; Blood Chemical Analysis; Central Nervous Syste

1970
[Problems raised by combinations of toxic agents].
    Minerva anestesiologica, 1972, Volume: 38, Issue:4

    Topics: Atropine; Barbiturates; Blood Pressure; Drug Antagonism; Drug Incompatibility; Drug Interactions; Et

1972
[Clinical course and therapy of a successfully treated severe bromisovalerinylcarbamide, methaqualone, and meprobamate poisoning in a 12-year-old child].
    Archiv fur Toxikologie, 1973, Volume: 30, Issue:2

    Topics: Blood Coagulation Factors; Bromides; Bromine; Butyrates; Carbamates; Child; Diuretics; Enzymes; Gast

1973
Evaluation of deaths from drug overdose. A clinicopathologic study.
    American journal of clinical pathology, 1974, Volume: 61, Issue:6

    Topics: Accidents; Adolescent; Adult; Aged; Barbiturates; Child; Chloroquine; Dextropropoxyphene; Female; Gl

1974
[Acute tranquilizer poisoning].
    Minerva medica, 1972, Feb-17, Volume: 63, Issue:12

    Topics: Acute Disease; Barbiturates; Cardiovascular Diseases; Humans; Meprobamate; Peritoneal Dialysis; Pois

1972
Hemodynamic effects of norepinephrine in severe hypnotic drug poisoning with arterial hypotension.
    Acta medica Scandinavica, 1972, Volume: 192, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Aged; Amitriptyline; Blood Pressure; Carbamazepine; Cardiac Output; Ca

1972
Accumulative prognostic index for patients with barbiturate, glutethimide and meprobamate intoxication.
    The New England journal of medicine, 1971, Dec-30, Volume: 285, Issue:27

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Barbiturates; Female; Glutethimide; Hemodynamics; Hum

1971
Rapid diagnosis of sedative intoxication by gas chromatography.
    Annals of internal medicine, 1970, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Barbiturates; Chromatography, Gas; Coma; Female; Glutethimide; Humans; Hypnotics

1970
[Thin layer standard chromatograms of hypnotics and meprobmate after passage through the body].
    Das Medizinische Laboratorium, 1970, Volume: 23, Issue:11

    Topics: Adult; Barbiturates; Chromatography, Thin Layer; Female; Humans; Hypnotics and Sedatives; Male; Mepr

1970
[Physiopathologic and therapeutic problems raised by acute toxic pulmonary edema].
    Le Poumon et le coeur, 1970, Volume: 26, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Barbiturates; Carbon Monoxide Poisoning; Child; Child, Prescho

1970
[Value of the electroencephalographic surveillance in the framework of resuscitation of comas from acute medicinal poisoning].
    Revue neurologique, 1967, Volume: 117, Issue:3

    Topics: Barbiturates; Brain; Coma; Electroencephalography; Humans; Imipramine; Meprobamate; Phenothiazines;

1967
A system of screening for the presence of a number of common drugs.
    Journal of clinical pathology, 1967, Volume: 20, Issue:2

    Topics: Barbiturates; Blood Chemical Analysis; Bromides; Butyrates; Carbon Monoxide; Chromatography, Thin La

1967
[Forced diuresis (osmotic diuresis) in acute poisoning].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1968, Volume: 119, Issue:1

    Topics: Acids; Acute Disease; Adolescent; Adult; Alkalies; Barbiturates; Diuretics; Female; Humans; Hypnotic

1968
Acute meprobamate poisoning. A fatal case following a lucid interval.
    JAMA, 1969, Jan-13, Volume: 207, Issue:2

    Topics: Female; Humans; Infusions, Parenteral; Meprobamate; Middle Aged; Poisoning

1969