Page last updated: 2024-10-30

meprobamate and Muscle Contraction

meprobamate has been researched along with Muscle Contraction in 12 studies

Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Pentobarbital and Sulpiride produce a biphasyc effect of opposite sign: at small doses Pentobarbital increases the stretch response while Sulpiride reduces it."1.26[Action of some psychotropic drugs on the electrmyographic response evoked by stretches of the gastrocnemius muscle of rats submitted to stress]. ( Eandi, M; Ricci Gamalero, S; Taglia, P, 1980)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Williams, JG1
Williams, B1
Glassman, JM1
Soyka, JP1
Pollack, M1
Eandi, M1
Ricci Gamalero, S1
Taglia, P1
Leeuwin, RS1
Djojodibroto, RD1
Groenewoud, ET1
Fubini, B1
Molinengo, L1
Cymbalist, MA1
Shapero, M1
Leszkovszky, GP1
Korbonits, D1
Caprino, L1
Borrelli, F1
Falchetti, R1
Ellis, KO1
Carpenter, JF1
Robichaud, RC1
Gylys, JA1
Sledge, KL1
Hillyard, IW1
Jusic, A1
Dogan, S1
Stojanovic, V1
Agarwal, SL1
Bhargava, V1

Trials

1 trial available for meprobamate and Muscle Contraction

ArticleYear
Treatment of muscle contraction headache: Micrainin vs. aspirin.
    Headache, 1982, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combi

1982

Other Studies

11 other studies available for meprobamate and Muscle Contraction

ArticleYear
The effect of meprobamate on the somatic responses of anxious patients and normal controls.
    Psychophysiology, 1967, Volume: 3, Issue:4

    Topics: Adult; Anxiety Disorders; Electromyography; Feedback; Female; Humans; Meprobamate; Muscle Contractio

1967
[Action of some psychotropic drugs on the electrmyographic response evoked by stretches of the gastrocnemius muscle of rats submitted to stress].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jun-30, Volume: 56, Issue:12

    Topics: Amitriptyline; Animals; Chlorpromazine; Dextroamphetamine; Meprobamate; Muscle Contraction; Muscle R

1980
The effects of three benzodiazepines and of meprobamate on the action of smooth muscle stimulants on the guinea-pig ileum.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 217, Issue:1

    Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Drug Interactions; Flurazep

1975
[Depression of muscle contraction: molecular weight of drugs and temperature].
    Bollettino della Societa italiana di biologia sperimentale, 1975, Dec-15, Volume: 51, Issue:23

    Topics: Alcohols; Animals; Chloral Hydrate; Colchicine; Emetine; Meprobamate; Molecular Weight; Muscle Contr

1975
A comparative study of the effect of some centrally acting skeletal muscle relaxants in mice.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: Animals; Dioxins; Dose-Response Relationship, Drug; Ethers; Male; Mephenesin; Meprobamate; Methocarb

1974
[On the pharmacology of new isoquinoline derivatives].
    Die Pharmazie, 1967, Volume: 22, Issue:8

    Topics: Anesthetics, Local; Animals; Antihypertensive Agents; Atropine; Barbiturates; Blood Pressure; Centra

1967
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha

1973
A comparative study of dantrolene sodium and other skeletal muscle relaxants with the Straub tail mouse.
    Neuropharmacology, 1974, Volume: 13, Issue:3

    Topics: Anesthetics, Local; Animals; Chlordiazepoxide; Chlorpromazine; Dantrolene; Diazepam; Gallamine Triet

1974
The pharmacology of prazepam. A new benzodiazepine derivative.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 185, Issue:2

    Topics: Aggression; Animals; Avoidance Learning; Behavior, Animal; Benzazepines; Cats; Chlordiazepoxide; Dia

1970
Hereditary persistent distal cramps.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:3

    Topics: Action Potentials; Adolescent; Adult; Age Factors; Aged; Anesthesia, Spinal; Carbamazepine; Child; E

1972
Study of the effects of tranquillizers on the acetylcholine, 5 hydroxytryptamine, adrenaline and nor-adrenaline responses of the cardiac, smooth and skeletal muscle.
    Indian journal of physiology and pharmacology, 1964, Volume: 8, Issue:4

    Topics: Acetylcholine; Animals; Anura; Chlorpromazine; Epinephrine; Guinea Pigs; Heart; Intestines; Meprobam

1964