Page last updated: 2024-10-30

meprobamate and Drug Overdose

meprobamate has been researched along with Drug Overdose in 16 studies

Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"Clobazam is a benzodiazepine with anti-anxiety and anticonvulsant properties marketed in several countries."1.36Blood concentrations of clobazam and norclobazam in a lethal case involving clobazam, meprobamate and clorazepate. ( Charpenel-Durat, C; De Meo, P; De Saint Léger, MN; Duval, ML; Kuhlmann, E; Mauras, M; Navarette, C; Pok, PR, 2010)
"Meprobamate was also found as the metabolite of carisoprodol in both urine and plasma."1.32Simultaneous determination of carisoprodol and acetaminophen in an attempted suicide by liquid chromatography-mass spectrometry with positive electrospray ionization. ( Aoki, M; Maeno, Y; Matsumoto, T; Matsuoka, T; Nagao, M; Sano, T, 2003)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ceschi, A1
Berger, D1
Dickenmann, M1
Bodmer, M1
Fanton, L2
Bevalot, F2
Gustin, MP2
Paultre, CZ1
Le Meur, C2
Malicier, D2
Buire, AC1
Vitry, F1
Hoizey, G1
Lamiable, D1
Trenque, T1
Pok, PR1
Mauras, M1
De Saint Léger, MN1
Kuhlmann, E1
Charpenel-Durat, C1
Navarette, C1
Duval, ML1
De Meo, P1
Cartiser, N1
Gaillard, Y1
Guitton, J1
Matsumoto, T1
Sano, T1
Matsuoka, T1
Aoki, M1
Maeno, Y1
Nagao, M1
BRILL, B2
CHARET, R2
ELLOSO, C2
HIESTAND, EC2
KAMIN, I1
SHASKAN, DA1
BLUMBERG, AG1
ROSETT, HL1
DOBROW, A1
FERGUSON, MJ1
GERMANOS, S1
GRACE, WJ1
STEVENS, AE1
NEWTON, RM1
Osváth, P1
Fekete, S1
Matsika, MD1
Tournier, M1
Lagnaoui, R1
Pehourcq, F1
Molimard, M1
Bégaud, B1
Verdoux, H1
Moore, N1
Lambert, WE1
De Leenheer, AP1
Van Bocxlaer, JF1
Piette, M1

Other Studies

16 other studies available for meprobamate and Drug Overdose

ArticleYear
Pharmacokinetics of meprobamate in overdose treated with continuous venovenous hemodiafiltration (CVVHDF).
    Hemodialysis international. International Symposium on Home Hemodialysis, 2013, Volume: 17, Issue:4

    Topics: Acute Kidney Injury; Drug Overdose; Female; Hemodiafiltration; Humans; Meprobamate; Middle Aged; Sui

2013
Interpretation of drug concentrations in an alternative matrix: the case of meprobamate in bile.
    International journal of legal medicine, 2009, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bile; Drug Overdose; Female; Forensic Toxicology; Gas Ch

2009
Overdose of meprobamate: plasma concentration and Glasgow Coma Scale.
    British journal of clinical pharmacology, 2009, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Drug Overdose; Female; Glasgow Coma Scale; Humans; Mal

2009
Blood concentrations of clobazam and norclobazam in a lethal case involving clobazam, meprobamate and clorazepate.
    Legal medicine (Tokyo, Japan), 2010, Volume: 12, Issue:6

    Topics: Aged; Anticonvulsants; Autopsy; Benzodiazepines; Clobazam; Clorazepate Dipotassium; Drug Overdose; F

2010
Using bone marrow matrix to analyze meprobamate for forensic toxicological purposes.
    International journal of legal medicine, 2013, Volume: 127, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Marrow; Drug Overdose; Female; Forensic Toxicology;

2013
Simultaneous determination of carisoprodol and acetaminophen in an attempted suicide by liquid chromatography-mass spectrometry with positive electrospray ionization.
    Journal of analytical toxicology, 2003, Volume: 27, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Carisoprodol; Chromatography, Liquid; Drug Combinati

2003
Coma after miltown overdose.
    Annals of internal medicine, 1956, Volume: 45, Issue:6

    Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate

1956
Coma after miltown overdose.
    Annals of internal medicine, 1956, Volume: 45, Issue:6

    Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate

1956
Coma after miltown overdose.
    Annals of internal medicine, 1956, Volume: 45, Issue:6

    Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate

1956
Coma after miltown overdose.
    Annals of internal medicine, 1956, Volume: 45, Issue:6

    Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate

1956
Overdosage with meprobamate; presentation of case.
    The Ohio State medical journal, 1956, Volume: 52, Issue:12

    Topics: Drug Overdose; Humans; Meprobamate

1956
Overdosage with meprobamate; presentation of case.
    The Ohio State medical journal, 1956, Volume: 52, Issue:12

    Topics: Drug Overdose; Humans; Meprobamate

1956
Overdosage with meprobamate; presentation of case.
    The Ohio State medical journal, 1956, Volume: 52, Issue:12

    Topics: Drug Overdose; Humans; Meprobamate

1956
Overdosage with meprobamate; presentation of case.
    The Ohio State medical journal, 1956, Volume: 52, Issue:12

    Topics: Drug Overdose; Humans; Meprobamate

1956
Death due to massive overdose of meprobamate.
    The American journal of psychiatry, 1959, Volume: 115, Issue:12

    Topics: Death; Drug Overdose; Humans; Meprobamate; Suicide

1959
Severe hypotensive reactions following meprobamate overdosage.
    Annals of internal medicine, 1959, Volume: 51

    Topics: Drug Overdose; Humans; Hypotension; Meprobamate

1959
Meprobamate overdosage. A report on the management of five cases.
    Archives of internal medicine, 1960, Volume: 106

    Topics: Disease Management; Drug Overdose; Meprobamate

1960
Hypotension due to meprobamate overdose.
    British medical journal, 1960, Apr-02, Volume: 1, Issue:5178

    Topics: Drug Overdose; Humans; Hypotension; Meprobamate

1960
Transient, unilateral sensory and motor changes following meprobamate overdosage.
    Virginia medical monthly, 1961, Volume: 88

    Topics: Drug Overdose; Humans; Meprobamate; Neurologic Manifestations

1961
[Characteristics of the choice of psychotropic drugs in suicide attempts].
    Orvosi hetilap, 2003, Jan-19, Volume: 144, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents

2003
Comparison of patient questionnaires and plasma assays in intentional drug overdoses.
    Basic & clinical pharmacology & toxicology, 2004, Volume: 95, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Drug Ov

2004
Meprobamate intoxication: rare and difficult to find.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:4

    Topics: Drug Overdose; Female; Humans; Meprobamate; Middle Aged

1992