meprobamate and Coma
meprobamate has been researched along with Coma in 24 studies
Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twenty-five patients in grade IV coma have been treated with the column for treatment of drug overdose or agricultural chemical poisoning; the clinical course of one meprobamate-poisoned patient is described in detail." | 3.66 | A hemoperfusion column based on activated carbon granules coated with an ultrathin membrane of cellulose acetate. ( Bantjes, A; Dijkhuis, IC; Feijen, J; Tijssen, J; van Dijk, B; van Doorn, AW; Vonk, CR, 1979) |
| "Meprobamate was implicated in 50 (6." | 1.26 | Meprobamate overdosage: a continuing problem. ( Allen, MD; Greenblatt, DJ; Noel, BJ, 1977) |
Research
Studies (24)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (95.83) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| BRILL, B | 2 |
| CHARET, R | 2 |
| ELLOSO, C | 2 |
| TROY, CA | 1 |
| BEDSON, HS | 1 |
| FASSINA, G | 1 |
| HALS, H | 1 |
| Takeda, M | 1 |
| Yoshimura, H | 1 |
| Tsukamoto, H | 1 |
| Goulon, M | 1 |
| Nouailhat, F | 1 |
| Lévy-Alcover, MA | 1 |
| Dordain, G | 1 |
| Mellerio, F | 2 |
| Lin, JL | 1 |
| Lim, PS | 1 |
| Tijssen, J | 1 |
| Bantjes, A | 1 |
| van Doorn, AW | 1 |
| Feijen, J | 1 |
| van Dijk, B | 1 |
| Vonk, CR | 1 |
| Dijkhuis, IC | 1 |
| Allen, MD | 1 |
| Greenblatt, DJ | 1 |
| Noel, BJ | 1 |
| Kurtz, D | 2 |
| Feuerstein, J | 2 |
| Weber, M | 2 |
| Reeb, M | 2 |
| Rohmer, F | 2 |
| Wallace, JE | 1 |
| Blum, K | 1 |
| Singh, JM | 1 |
| Castell, DO | 1 |
| Sode, J | 1 |
| Lanzoni, V | 1 |
| Bloomer, HA | 1 |
| Maddock, RK | 1 |
| Sheehe, JB | 1 |
| Adams, EJ | 1 |
| Jouglard, J | 1 |
| Imbert, M | 1 |
| Fogliani, J | 1 |
| Fermaglich, JL | 1 |
| Mantz, JM | 1 |
| Hamann, B | 1 |
| Tempe, JD | 1 |
| Storck, D | 1 |
| Otteni, JC | 1 |
| Martin, G | 1 |
| Gaultier, M | 1 |
| Fournier, E | 1 |
| Bismuth, C | 2 |
| Rapin, J | 1 |
| Fréjaville, JP | 3 |
| Gluckman, JC | 3 |
| Migdal, A | 1 |
| Silverman, D | 1 |
| Saunders, MG | 1 |
| Schwab, RS | 1 |
| Masland, RL | 1 |
Reviews
2 reviews available for meprobamate and Coma
| Article | Year |
|---|---|
Determination of drugs in biologic specimens--a review.
Topics: Amphetamine; Amphetamines; Autoanalysis; Barbiturates; Chemical Phenomena; Chemistry; Chromatography | 1974 |
Drug-induced coma.
Topics: Alcoholic Intoxication; Barbiturates; Coma; Glutethimide; Humans; Meprobamate; Phenothiazines; Poiso | 1968 |
Other Studies
22 other studies available for meprobamate and Coma
| Article | Year |
|---|---|
Coma after miltown overdose.
Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate | 1956 |
Coma after miltown overdose.
Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate | 1956 |
Coma after miltown overdose.
Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate | 1956 |
Coma after miltown overdose.
Topics: Ascomycota; Child; Coma; Drug Overdose; Humans; Infant; Meprobamate | 1956 |
A case of meprobamate coma with convulsions.
Topics: Coma; Humans; Meprobamate; Seizures; Suicide | 1958 |
Coma due to meprobamate intoxication; report of a case confirmed by chemical analysis.
Topics: Coma; Humans; Meprobamate | 1959 |
[Antagonistic action of analeptics in meprobamate-induced experimental coma].
Topics: Central Nervous System Stimulants; Coma; Hostility; Meprobamate; Musculoskeletal Physiological Pheno | 1959 |
[Acute meprobamate poisoning: 7 cases with coma as the predominating symptom].
Topics: Ascomycota; Coma; Meprobamate | 1959 |
[Metabolism of drugs. LIV. On the pharmacological action of carbamate N-glucuronides].
Topics: Animals; Carbamates; Coma; Glucuronates; Male; Meprobamate; Mice; Pentobarbital; Rats; Seizures; Ure | 1966 |
[Toxic coma with autonomic sideration, with a favorable outcome].
Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam; | 1967 |
[EEG in the prognosis of toxic coma: reflections apropos of unusual data].
Topics: Alpha Rhythm; Anti-Anxiety Agents; Antipsychotic Agents; Barbiturates; Benzodiazepines; Body Tempera | 1982 |
Continuous arteriovenous hemoperfusion in acute poisoning.
Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Coma; Fatal Outcome; Female; Hemodynamics; Hemoperfusion | 1994 |
A hemoperfusion column based on activated carbon granules coated with an ultrathin membrane of cellulose acetate.
Topics: Acetates; Cellulose; Charcoal; Coma; Hemoperfusion; Humans; Membranes, Artificial; Meprobamate; Pois | 1979 |
Meprobamate overdosage: a continuing problem.
Topics: Adolescent; Adult; Barbiturates; Benactyzine; Coma; Ethanol; Female; Humans; Hypnotics and Sedatives | 1977 |
Value of EEG monitoring in reanimation of comas due to acute drug intoxication.
Topics: Amitriptyline; Coma; Diazepam; Electroencephalography; Humans; Imipramine; Meprobamate; Phenothiazin | 1968 |
Meprobamate intoxication treated with peritoneal dialysis.
Topics: Adult; Coma; Humans; Male; Meprobamate; Peritoneal Dialysis | 1967 |
Rapid diagnosis of sedative intoxication by gas chromatography.
Topics: Adolescent; Adult; Barbiturates; Chromatography, Gas; Coma; Female; Glutethimide; Humans; Hypnotics | 1970 |
[A case of fatal poisoning by Equanil].
Topics: Acute Disease; Coma; Female; Hemodynamics; Humans; Hypotension; Meprobamate; Methaqualone; Middle Ag | 1970 |
Determining cerebral death.
Topics: Autopsy; Barbiturates; Brain; Brain Death; Cognition; Coma; Death; Diagnosis, Differential; Electroc | 1971 |
[Value of the electroencephalographic surveillance in the framework of resuscitation of comas from acute medicinal poisoning].
Topics: Barbiturates; Brain; Coma; Electroencephalography; Humans; Imipramine; Meprobamate; Phenothiazines; | 1967 |
[Acute poisoning by meprobamate. Apropos of 141 cases].
Topics: Animals; Coma; Dogs; Humans; Mannitol; Meprobamate; Mice; Pulmonary Embolism; Rats | 1968 |
[Apropos of acute poisoning with meprobamate. An unusual electroclinical case].
Topics: Adult; Anuria; Blood Circulation; Coma; Electroencephalography; Humans; Male; Meprobamate; Metaramin | 1968 |
[Acute massive poisoning by meprobamate].
Topics: Cardiovascular Diseases; Coma; Humans; Meprobamate | 1969 |
[A case of crisis in chronic adrenal failure provoked by meprobamate].
Topics: Addison Disease; Adrenal Insufficiency; Coma; Female; Humans; Meprobamate; Middle Aged | 1969 |
Cerebral death and the electroencephalogram. Report of the ad hoc committee of the American Electroencephalographic Society on EEG Criteria for determination of cerebral death.
Topics: Adult; Aged; Barbiturates; Brain; Child; Coma; Death; Drowning; Electroencephalography; Heart Arrest | 1969 |