meprobamate has been researched along with Clostridium tetani Infection in 23 studies
Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anti-tetanus activity of a number of phenothiazine derivatives and other centrally acting muscle relaxants, such as mephenesin, dicyclopropyl ketoxime, 2-amino-6-methylbenzothiazole and meprobamate, has been determined in rabbits with experimental local tetanus." | 3.64 | Centrally acting muscle relaxants in tetanus. ( WEBSTER, RA, 1961) |
| "Further evaluation of this drug is essential with emphasis on establishment of pediatric dosage schedules and to further confirm reliability." | 1.24 | Newer concepts in the management of tetanus. ( COCK, TC, 1961) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PERLSTEIN, MA | 3 |
| TURNER, M | 1 |
| ELAM, H | 1 |
| WAINO ANDERSEN, E | 1 |
| KJAER, K | 1 |
| DAMANY, SJ | 1 |
| KAMAT, GR | 1 |
| COCK, TC | 1 |
| TALSTAD, I | 1 |
| JORGENSEN, KR | 1 |
| LOU, H | 1 |
| ZUCK, D | 1 |
| GNATZY, H | 1 |
| WEBSTER, RA | 1 |
| DEINHART, W | 1 |
| HARRISON, GA | 1 |
| ROSEN, M | 1 |
| GOODALL, P | 1 |
| NASSER, WK | 1 |
| RUIZSANCHEZ, F | 1 |
| RUIZSANCHEZ, A | 1 |
| NEGRETE, D | 1 |
| ARIAS, S | 1 |
| CHEN, TC | 1 |
| MOLLARET, P | 1 |
| POCIDALO, JJ | 1 |
| HOWARD, FH | 1 |
| DEVERE, W | 1 |
| Bernhardt, LC | 1 |
| Hickey, RC | 1 |
| Weinstein, L | 1 |
| McNiel, JR | 1 |
| Zítko, K | 1 |
| Racenberg, E | 1 |
| Nilsson, E | 1 |
1 review available for meprobamate and Clostridium tetani Infection
| Article | Year |
|---|---|
Tetanus.
Topics: Central Nervous System; Chlorpromazine; Diazepam; Humans; Hypnotics and Sedatives; Meprobamate; Neur | 1973 |
1 trial available for meprobamate and Clostridium tetani Infection
| Article | Year |
|---|---|
A controlled study of intramuscular meprobamate in neonatal tetanus.
Topics: Chlorpromazine; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, Newborn, Diseases; Inject | 1966 |
21 other studies available for meprobamate and Clostridium tetani Infection
| Article | Year |
|---|---|
Electromyographic observations in patients with tetanus: with special reference to the effect of drugs.
Topics: Chlorpromazine; Electromyography; Humans; Meprobamate; Pentobarbital; Tetanus | 1958 |
[Tetanus treated with meprobamate (restenil)].
Topics: Meprobamate; Tetanus; Tetanus Toxoid | 1958 |
Meprobamate in tetanus.
Topics: Humans; Meprobamate; Tetanus | 1958 |
Control of tetanus spasms by administration of meprobamate.
Topics: Humans; Meprobamate; Spasm; Tetanus; Tetanus Toxoid | 1959 |
Newer concepts in the management of tetanus.
Topics: California; Child; Humans; Meprobamate; Reproducibility of Results; Tetanus; Tetanus Toxoid | 1961 |
[Treatment of tetanus with meprobamate].
Topics: Meprobamate; Tetanus; Tetanus Toxoid | 1960 |
[2 cases of tetanus treated with intramuscular meprobamate].
Topics: Humans; Injections, Intramuscular; Meprobamate; Tetanus | 1961 |
Meprobamate in tetanus.
Topics: Meprobamate; Tetanus | 1960 |
[On control of spasm in tetanus by administration of meprobamate].
Topics: Meprobamate; Spasm; Tetanus; Tetanus Toxoid | 1960 |
Centrally acting muscle relaxants in tetanus.
Topics: Animals; Mephenesin; Meprobamate; Muscle Relaxants, Central; Rabbits; Structure-Activity Relationshi | 1961 |
[The treatment of tetanus with meprobamate].
Topics: Meprobamate; Tetanus; Tetanus Toxoid | 1963 |
HAEMORRHAGIC COMPLICATIONS DURING THE TREATMENT OF TETANUS.
Topics: Amobarbital; Child; Chloramphenicol; Chlorpromazine; Diphenhydramine; Hematuria; Hemolysis; Hydrocor | 1964 |
CLINICAL TETANUS: TREATMENT OF TEN CASES.
Topics: Chlorpromazine; Debridement; Desensitization, Immunologic; Erythromycin; Humans; Injections; Injecti | 1964 |
[BENZODIAZEPINE AS A COADJUVANT IN THE TREATMENT OF TETANUS].
Topics: Anti-Bacterial Agents; Benzodiazepines; Chlorpromazine; Diazepam; Drug Therapy; Erythromycin; Humans | 1964 |
[ON THE MECHANISM OF ACTION OF ANDAXIN IN EXPERIMENTAL TETANUS].
Topics: Animals; Electroencephalography; Electromyography; Lagomorpha; Meprobamate; Pharmacology; Rabbits; R | 1964 |
HYPOVENTILATION IN PATIENTS WITH NORMAL LUNGS. MANAGEMENT OF DRUG POISONING, TETANUS, AND MYASTHENIA GRAVIS.
Topics: Antidotes; Barbiturates; Cholinesterase Inhibitors; Glutethimide; Humans; Hypoventilation; Meprobama | 1965 |
Intramuscular meprobamate in the treatment of tetanus in infants and children.
Topics: Child; Humans; Infant; Injections, Intramuscular; Meprobamate; Tetanus | 1962 |
Tetanus. Its prophylaxis and treatment.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Debridement; gamma-Globulin | 1966 |
[The mixed block--its therapeutic application].
Topics: Autonomic Nerve Block; Chlorprothixene; Decamethonium Compounds; Drug Synergism; Humans; Meprobamate | 1968 |
Treatment of tetanus.
Topics: Humans; Meprobamate; Tetanus | 1969 |
Modern tetanus treatment.
Topics: Barbiturates; Chlorpromazine; Drug Hypersensitivity; Humans; Hyperbaric Oxygenation; Injections, Int | 1966 |