Page last updated: 2024-10-30

meprobamate and Chronic Insomnia

meprobamate has been researched along with Chronic Insomnia in 21 studies

Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

Research Excerpts

ExcerptRelevanceReference
"Carisoprodol is a commonly used centrally acting muscle relaxant."1.34Is the frequency of carisoprodol withdrawal syndrome increasing? ( Hammer, JS; Pendarvis, RO; Reeves, RR, 2007)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199019 (90.48)18.7374
1990's0 (0.00)18.2507
2000's2 (9.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BRECHMANN, H1
KRANTZ, JC1
RICKELS, K1
BASS, H1
BALLAS, R1
LEBLOIS, J1
PONT, M1
CHAPUY, A1
VEDRINNE, J1
BOURNET, P1
WAGRET, G1
CHARRIOT, G1
LAMBERT, PA1
BATTERMAN, RC1
MATTHEWS, V1
LEHMANN, HE1
BAN, TA1
Reeves, RR1
Hammer, JS1
Pendarvis, RO1
Exton-Smith, AN1
Dry, J1
Pradalier, A1
Leynadier, F1
Zung, WW1
Chesrow, EJ1
Kaplitz, SE1
D'Cruz, IA1
Ramamoorthy, K1
Shanbhag, SK1
Darbar, AK1
Kómár, J1
Pólay, E1
Le Borgne, Y1
Haumonte, MT1
Pfitzenmeyer, J1
Wurtz, D1
Printz, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Feasibility and Efficacy of an Internet-delivered Cognitive-behavioral Intervention for Insomnia in a National Cohort of Danish Breast Cancer Survivors[NCT02444026]225 participants (Anticipated)Interventional2014-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for meprobamate and Chronic Insomnia

ArticleYear
The pharmacology of disordered sleep: a laboratory approach.
    International psychiatry clinics, 1970, Volume: 7, Issue:2

    Topics: Amitriptyline; Anxiety; Arousal; Barbiturates; Brain; Cerebral Cortex; Depression; Desipramine; Huma

1970

Trials

2 trials available for meprobamate and Chronic Insomnia

ArticleYear
Sustained-release tranquilizer therapy in hospitalized geriatric patients.
    Journal of the American Geriatrics Society, 1970, Volume: 18, Issue:1

    Topics: Aged; Anxiety; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparations; Hospitalizati

1970
Comparison of two non-barbiturate hypnotics--methaqualone hydrochloride and meprobamate; a double-blind controlled clinical trial.
    The Journal of the Association of Physicians of India, 1966, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Meprobamate; Methaqualone;

1966

Other Studies

18 other studies available for meprobamate and Chronic Insomnia

ArticleYear
Sleep complaints: Whenever possible, avoid the use of sleeping pills.
    Prescrire international, 2008, Volume: 17, Issue:97

    Topics: Acupuncture Therapy; Adult; Aged; Behavior Therapy; Benzodiazepines; Clinical Trials as Topic; Conge

2008
[Modern therapy of autochthonous states of excitation & insomnia].
    Medizinische Klinik, 1958, Jun-27, Volume: 53, Issue:26

    Topics: Emotions; Humans; Meprobamate; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders

1958
Management of insomnia and restlessness; a pharmacologic viewpoint.
    Connecticut medicine, 1958, Volume: 22, Issue:8

    Topics: Anxiety; Humans; Hypnotics and Sedatives; Meprobamate; Movement; Psychomotor Agitation; Sleep Initia

1958
A comparative controlled clinical trial of seven hypnotic agents in medical and psychiatric in-patients.
    The American journal of the medical sciences, 1963, Volume: 245

    Topics: Chloral Hydrate; Glutethimide; Humans; Hypnotics and Sedatives; Meprobamate; Secobarbital; Sleep Ini

1963
[MEPROBAMATE IN OBSTETRICS].
    El Dia medico, 1963, Sep-02, Volume: 35

    Topics: Anxiety; Anxiety Disorders; Female; Humans; Mental Disorders; Meprobamate; Obstetrics; Pregnancy; Pr

1963
[STUDY OF THE HYPNOTIC POWER OF A NEW THERAPEUTIC COMBINATION: MEPROBAMATE-CB 1664].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1964, Volume: 9

    Topics: Geriatrics; Humans; Hypnotics and Sedatives; Meprobamate; Research; Sleep Initiation and Maintenance

1964
[ANXIETY AND INSOMNIA. APROPOS OF A NEW MEDICAMENTOUS COMBINATION: LE FH 040-3].
    Lyon medical, 1964, Feb-23, Volume: 211

    Topics: Anxiety; Anxiety Disorders; Drug Combinations; Humans; Meprobamate; Sleep Initiation and Maintenance

1964
[THERAPEUTIC STUDY OF A NEW MEDICAMENTOUS COMBINATION: FH-040-3].
    Journal de medecine de Lyon, 1964, Jun-05, Volume: 45

    Topics: Dementia; Drug Combinations; Geriatrics; Humans; Mental Disorders; Meprobamate; Neurotic Disorders;

1964
[THERAPEUTIC EFFECTS OF A HYPNOTIC COMPOUND WITH TRANQUILIZING PROPERTIES].
    Lyon medical, 1964, Jun-07, Volume: 211

    Topics: Anxiety; Anxiety Disorders; Depression; Humans; Hypnotics and Sedatives; Meprobamate; Neurotic Disor

1964
SUSTAINED-ACTION AMPHETAMINE-MEPROBAMATE COMBINATION FOR THE TREATMENT OF OBESITY.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Amphetamine; Amphetamines; Appetite Depressants; Biomedical Research; Delayed-Action Preparations; D

1964
A COMPARATIVE STUDY OF THIRTEEN HYPNOTIC DRUGS.
    Applied therapeutics, 1964, Volume: 6

    Topics: Barbiturates; Biomedical Research; Chloral Hydrate; Chlorprothixene; Ethchlorvynol; Glutethimide; Hu

1964
Is the frequency of carisoprodol withdrawal syndrome increasing?
    Pharmacotherapy, 2007, Volume: 27, Issue:10

    Topics: Adult; Anxiety; Carisoprodol; Female; Hallucinations; Humans; Meprobamate; Muscle Relaxants, Central

2007
The use and abuse of hypnotics.
    Gerontologia clinica, 1967, Volume: 9, Issue:4

    Topics: Aged; Amobarbital; Antidepressive Agents; Antipyrine; Chloral Hydrate; Humans; Hypnotics and Sedativ

1967
[Use of non-barbiturate medications as hypnotics. Concerns and limits].
    Semaine des hopitaux. Therapeutique, 1977, Volume: 53, Issue:2

    Topics: Alcohols; Anti-Anxiety Agents; Benzodiazepines; Glutethimide; Histamine H1 Antagonists; Humans; Hypn

1977
[The restless legs syndrome].
    Munchener medizinische Wochenschrift (1950), 1970, Jul-31, Volume: 112, Issue:31

    Topics: Amyloidosis; Anemia; Avitaminosis; Calcium; Cholesterol; Electromyography; Female; Humans; Iron; Leg

1970
[On the effects of a new hypno-sedating, non-barbituric agent, FH 040-3 in sleep disorders].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1967, Volume: 144, Issue:9

    Topics: Drug Synergism; Humans; Meprobamate; Promethazine; Sleep Initiation and Maintenance Disorders

1967
[Preparations of meprobamate in tablet form].
    La Clinica terapeutica, 1967, Mar-31, Volume: 40, Issue:6

    Topics: Anxiety; Female; Humans; Mental Disorders; Meprobamate; Premenstrual Syndrome; Skin Diseases; Sleep

1967
[Clinical study of a new somnifacient: F.H. 040-3 C.B].
    Annales medico-psychologiques, 1966, Volume: 124, Issue:5

    Topics: Alcoholism; Humans; Hypnotics and Sedatives; Mental Disorders; Meprobamate; Phenothiazines; Sleep In

1966