Page last updated: 2024-10-30

meprobamate and Chemical Dependence

meprobamate has been researched along with Chemical Dependence in 106 studies

Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

Research Excerpts

ExcerptRelevanceReference
"Meprobamate was indistinguishable from placebo on euphoria and abuse potential scales."2.71Comparative abuse liability and pharmacological effects of meprobamate, triazolam, and butabarbital. ( Busto, UE; Greenblatt, DJ; Kaplan, HL; Sellers, EM; Zawertailo, LA, 2003)
" Generally, both LZ and MEP produced comparable dose-related effects; LZ had a more rapid onset of action and on several measures showed a more shallow dose-response curve than MEP."2.66Lorazepam and meprobamate dose effects in humans: behavioral effects and abuse liability. ( Griffiths, RR; Roache, JD, 1987)
" Uncontrolled long-term administration is to be rejected in all circumstances, and supply should be strictly on prescription only in order to prevent uncontrolled acquisition."2.64The use of tranquilizers in the treatment of mixed drug abuse. ( Demel, I; Kryspin-Exner, K, 1975)
"Carisoprodol is a therapeutic and occasionally abused centrally acting muscle relaxant."1.38Postmortem carisoprodol and meprobamate concentrations in blood and liver: lack of significant redistribution. ( Lucas, J; McIntyre, IM; Sherrard, J, 2012)
"Carisoprodol was developed to create a drug with less potential for abuse than meprobamate."1.34Carisoprodol use and abuse in Norway: a pharmacoepidemiological study. ( Bramness, JG; Engeland, A; Furu, K; Skurtveit, S, 2007)
" This result indicates a gene dosage effect where the carisoprodol : meprobamate ratio reflects the number of active CYP2C19 alleles."1.32Association between blood carisoprodol:meprobamate concentration ratios and CYP2C19 genotype in carisoprodol-drugged drivers: decreased metabolic capacity in heterozygous CYP2C19*1/CYP2C19*2 subjects? ( Bramness, JG; Fauske, L; Grung, M; Molven, A; Mørland, J; Skurtveit, S; Steen, VM, 2003)
"Carisoprodol is a centrally acting muscle relaxant commonly used for lower back pain."1.32Impairment due to intake of carisoprodol. ( Bramness, JG; Mørland, J; Skurtveit, S, 2004)
" Rats were treated orally with MPB (maintenance dosage = 800 mg/kg X 2/day), PHB (100 X 2) or COD (50 X 2) twice a day (10:00 a."1.27Physical dependence on meprobamate after repeated oral administration in rats. ( Nakamura, H; Shimizu, M, 1983)
"Meprobamate addiction was present in six patients."1.26The present status of meprobamate ingestion. A five-year review of cases with serum concentrations and clinical findings. ( Bailey, DN, 1981)

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-199098 (92.45)18.7374
1990's2 (1.89)18.2507
2000's5 (4.72)29.6817
2010's1 (0.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McIntyre, IM1
Sherrard, J1
Lucas, J1
Zawertailo, LA1
Busto, UE1
Kaplan, HL1
Greenblatt, DJ2
Sellers, EM1
Bramness, JG3
Skurtveit, S3
Fauske, L1
Grung, M1
Molven, A1
Mørland, J3
Steen, VM1
PHILLIPS, RM1
JUDY, FR1
JUDY, HE1
SWINYARD, EA1
CHIN, L1
FINGL, E1
EWING, JA4
FULLILOVE, RE1
KODAHL, T1
ANDREASSEN, J1
BILLIG, O1
BURRIS, BL1
GREAVES, DC1
WEST, LJ1
STOUGH, AR1
HAIZLIP, TM2
ZUCKER, AH2
MACHLIN, SD2
SCOTT, W2
ESSIG, CF1
MOHR, RC1
MEAD, BT1
BOYD, LJ1
CAMMER, L1
MULINOS, MG1
HUPPERT, VF1
HAMMER, H1
JONSSON, B1
TADDEI, I1
PANNI, E1
EITINGER, L2
RETTERSTOL, N4
SUND, A3
ALLGEN, LG2
ANDERSEN, K1
LUNDBERG, L1
SWANSON, LA1
OKADA, T1
SNOW, L1
RICKELS, K2
LITTLE, JC1
ACHTE, KA1
MCCORMICK, TC1
RAVNSBORG, IS1
BERGER, H1
BERLE, BB1
NYSWANDER, M1
HAMBURGER, E1
SOULAIRAC, A1
GEIER, S1
KARLSSON, KW1
RIVIN, AU1
GEORGE, WK1
STUBBS, JB1
VARENNE, G1
SATTES, H1
CHEN, IY1
WAY, EL1
HOLLISTER, LE1
GLAZENER, FS1
Furu, K1
Engeland, A1
Bakewell, WE1
Exton-Smith, AN1
Cohen, ES1
Holman, RC1
Gary, NE1
Tresznewsky, O1
Nakamura, H2
Shimizu, M2
Brooker, AE1
Wiens, AN1
Wiens, DA1
Malloy, TE1
Bailey, DN1
Littrell, RA1
Sage, T1
Miller, W1
Gonzales, JJ1
Emmerich, AD1
Rauch, SL1
Stern, TA1
Logan, BK1
Case, GA1
Gordon, AM1
Salomon, C1
Goldfinger, R1
Ahmed, KS1
Pitchumoni, CS1
Weseley, SA1
Goulding, R1
Kryspin-Exner, K3
Demel, I1
Banerjee, U3
Braun, J1
Jimerson, D1
Morrison, J1
Giannini, AJ1
Price, WA1
Giannini, MC1
Bjørneboe, A1
Bjørneboe, GE1
Gjerde, H1
Bugge, A1
Drevon, CA1
Roache, JD1
Griffiths, RR1
Husquinet, H1
Wallace, JE1
Blum, K1
Singh, JM1
Irey, NS1
Yanaura, S1
Suzuki, T1
Tagashira, E1
Nurimoto, S1
Katz, RL1
Bogdanoff, B1
Rorke, LB1
Yanoff, M1
Warren, WS1
Yanagita, T1
Takahashi, S1
Guelfi, JD1
Olivier-Martin, R1
Babbini, M1
Gaiardi, M1
Bartoletti, M1
Maronde, RF1
Silverman, M1
Kullberg, MP1
Gorodetzky, CW1
Lanzoni, V1
Davis, JM1
Bartlett, E1
Termini, BA1
Stika, L1
Vinar, O1
Chopra, GS1
Kato, M1
Kaufman, A1
Brickner, PW1
Varner, R1
Mashburn, W1
Shader, RI1
Bergsman, A1
Sandberg, A1
Bejerot, N1
Hellström, L1
Gastager, H1
Held, H1
von Oldershausen, HF1
Svestka, J1
Náhunek, K1
Smith, DE1
Wesson, DR1
Hofman, G1
Dunlop, M1
Curnow, DH1
Vondrácek, V1
Prokupek, J1
Fischer, R1
Ahrenbergová, M1
Harris, RT1
Claghorn, JL1
Schoolar, JC1
Andreani, F2
Valla, S2
Holmberg, MB1
Jansson, B1
Gomez, EA1
Pearson, MM1
Little, RB1
Ideström, CM1
Holmberg, G1
Czerwenka-Wenkstetten, H1
Hofmann, G1
Lange, E1
Rossner, M1
Oehme, P1
Lock, W1

Reviews

4 reviews available for meprobamate and Chemical Dependence

ArticleYear
Determination of drugs in biologic specimens--a review.
    Clinical toxicology, 1974, Volume: 7, Issue:5

    Topics: Amphetamine; Amphetamines; Autoanalysis; Barbiturates; Chemical Phenomena; Chemistry; Chromatography

1974
Sedatives and tranquilizers.
    The New England journal of medicine, 1972, Apr-06, Volume: 286, Issue:14

    Topics: Anxiety; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and S

1972
Drug-induced coma.
    The Surgical clinics of North America, 1968, Volume: 48, Issue:2

    Topics: Alcoholic Intoxication; Barbiturates; Coma; Glutethimide; Humans; Meprobamate; Phenothiazines; Poiso

1968
Overdosage of psychotropic drugs: a review. I. Major and minor tranquilizers.
    Diseases of the nervous system, 1968, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Child; Chlordiazepoxide; Humans; Male; Meprobamate; Phenothiazines; Substance-Rel

1968

Trials

5 trials available for meprobamate and Chemical Dependence

ArticleYear
Comparative abuse liability and pharmacological effects of meprobamate, triazolam, and butabarbital.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:3

    Topics: Adult; Analysis of Variance; Barbiturates; Behavior, Addictive; Dose-Response Relationship, Drug; Fe

2003
The use of tranquilizers in the treatment of mixed drug abuse.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adult; Alcoholism; Analgesics; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; F

1975
Lorazepam and meprobamate dose effects in humans: behavioral effects and abuse liability.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3

    Topics: Adult; Affect; Analysis of Variance; Behavior; Dose-Response Relationship, Drug; Humans; Lorazepam;

1987
Sedatives and tranquilizers.
    The New England journal of medicine, 1972, Apr-06, Volume: 286, Issue:14

    Topics: Anxiety; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and S

1972
Meprobamate: a study of irrational drug use.
    The American journal of psychiatry, 1971, Volume: 127, Issue:10

    Topics: Agranulocytosis; Anemia, Aplastic; Anxiety; Chlordiazepoxide; Diazepam; Humans; Meprobamate; Neuroti

1971

Other Studies

98 other studies available for meprobamate and Chemical Dependence

ArticleYear
Postmortem carisoprodol and meprobamate concentrations in blood and liver: lack of significant redistribution.
    Journal of analytical toxicology, 2012, Volume: 36, Issue:3

    Topics: Carisoprodol; Diagnosis; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Liver; M

2012
Association between blood carisoprodol:meprobamate concentration ratios and CYP2C19 genotype in carisoprodol-drugged drivers: decreased metabolic capacity in heterozygous CYP2C19*1/CYP2C19*2 subjects?
    Pharmacogenetics, 2003, Volume: 13, Issue:7

    Topics: Adult; Alleles; Aryl Hydrocarbon Hydroxylases; Carisoprodol; Cytochrome P-450 CYP2C19; Female; Gene

2003
Meprobamate addiction.
    Northwest medicine, 1957, Volume: 56, Issue:4

    Topics: Behavior, Addictive; Meprobamate; Substance-Related Disorders

1957
Withdrawal hyperexcitability following chronic administration of meprobamate to mice.
    Science (New York, N.Y.), 1957, Apr-19, Volume: 125, Issue:3251

    Topics: Animals; Behavior, Addictive; Meprobamate; Mice; Substance-Related Disorders

1957
Addiction to meprobamate.
    The New England journal of medicine, 1957, Jul-11, Volume: 257, Issue:2

    Topics: Humans; Meprobamate; Substance-Related Disorders

1957
[Risk of addiction to meprobamate].
    Ugeskrift for laeger, 1957, Aug-15, Volume: 119, Issue:33

    Topics: Meprobamate; Risk; Substance-Related Disorders

1957
Habituation to tranquilizing drugs.
    The Journal of the Tennessee State Medical Association. Tennessee State Medical Association, 1957, Volume: 50, Issue:10

    Topics: Behavior, Addictive; Chlorpromazine; Humans; Meprobamate; Substance-Related Disorders; Tranquilizing

1957
Convulsions following withdrawal from meprobamate; report of two cases.
    Southern medical journal, 1957, Volume: 50, Issue:12

    Topics: Humans; Meprobamate; Seizures; Substance-Related Disorders

1957
Possible habituating properties of meprobamate; clinical study in an institutionalized, highly susceptible population.
    Journal of the American Medical Association, 1958, Feb-22, Volume: 166, Issue:8

    Topics: Behavior, Addictive; Biomedical Research; Meprobamate; Substance-Related Disorders

1958
A controlled study of the habit forming propensities of meprobamate.
    The American journal of psychiatry, 1958, Volume: 114, Issue:9

    Topics: Behavior, Addictive; Habits; Meprobamate; Research Design; Substance-Related Disorders

1958
Meprobamate habituation: a controlled clinical study.
    The New England journal of medicine, 1958, Jun-12, Volume: 258, Issue:24

    Topics: Biomedical Research; Meprobamate; Research Design; Substance-Related Disorders

1958
An evaluation of meprobamate in opiate withdrawal.
    The American journal of psychiatry, 1958, Volume: 115, Issue:3

    Topics: Analgesics, Opioid; Conduct Disorder; Humans; Meprobamate; Substance-Related Disorders

1958
Withdrawal convulsions in dogs following chronic meprobamate intoxication.
    A.M.A. archives of neurology and psychiatry, 1958, Volume: 80, Issue:4

    Topics: Animals; Behavior, Addictive; Dogs; Meprobamate; Seizures; Substance-Related Disorders

1958
Meprobamate addiction.
    The New England journal of medicine, 1958, Oct-30, Volume: 259, Issue:18

    Topics: Humans; Meprobamate; Substance-Related Disorders

1958
An evaluation of meprobamate in opiate withdrawal.
    A.M.A. archives of neurology and psychiatry, 1958, Volume: 80, Issue:6

    Topics: Analgesics, Opioid; Conduct Disorder; Humans; Meprobamate; Opium; Substance-Related Disorders

1958
Meprobamate addiction.
    Journal of the American Medical Association, 1958, Dec-06, Volume: 168, Issue:14

    Topics: Behavior, Addictive; Meprobamate; Substance-Related Disorders

1958
[Cases of meprobamate abuse].
    Svenska lakartidningen, 1959, Feb-13, Volume: 56, Issue:7

    Topics: Behavior, Addictive; Humans; Mental Disorders; Meprobamate; Substance-Related Disorders

1959
[Pharmacological observations on the meprobamate habit].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Mar-15, Volume: 35, Issue:5

    Topics: Behavior, Addictive; Drugs, Investigational; Habits; Meprobamate; Substance-Related Disorders

1959
[Meprobamate; habituation and addiction to the preparation].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1960, Oct-01, Volume: 80

    Topics: Meprobamate; Substance-Related Disorders

1960
[Meprobamate analysis in clinic practice for the diagnosis of abuse or poisoning].
    Svenska lakartidningen, 1959, Jul-31, Volume: 56

    Topics: Ambulatory Care Facilities; Mental Disorders; Meprobamate; Substance-Related Disorders

1959
[Meprobamate addiction and habituation].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1962, Jan-01, Volume: 82

    Topics: Meprobamate; Substance-Related Disorders

1962
Death after withdrawal of meprobamate.
    JAMA, 1963, Jun-08, Volume: 184

    Topics: Death; Meprobamate; Seizures; Shock; Substance-Related Disorders

1963
[Meprobamate, habituation and addiction].
    Nordisk medicin, 1963, Jun-20, Volume: 69

    Topics: Behavior, Addictive; Humans; Meprobamate; Substance-Related Disorders

1963
The use of high dosage Deprol in alcoholic and narcotic withdrawal.
    The American journal of psychiatry, 1962, Volume: 119

    Topics: Alcoholism; Benactyzine; Humans; Meprobamate; Narcotics; Substance Withdrawal Syndrome; Substance-Re

1962
A CASE OF PRIMARY ADDICTION TO MEPROBAMATE.
    British medical journal, 1963, Sep-28, Volume: 2, Issue:5360

    Topics: Behavior, Addictive; Meprobamate; Substance-Related Disorders; Toxicology

1963
[THE PROBLEM OF SUICIDE].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1963, Volume: 17

    Topics: Alcoholism; Antidepressive Agents; Chlordiazepoxide; Counseling; Depression; Depressive Disorder; Fi

1963
TREATMENT OF MEPROBAMATE WITHDRAWAL SYNDROME.
    GP, 1964, Volume: 29

    Topics: Epilepsy; Epilepsy, Tonic-Clonic; Humans; Meprobamate; Neurologic Manifestations; Substance Withdraw

1964
[DRUG ADDICTION AMONG ALCOHOLICS].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1964, Apr-01, Volume: 84

    Topics: Alcoholics; Alcoholism; Barbiturates; Central Nervous System Stimulants; Humans; Meprobamate; Morphi

1964
TREATMENT OF NARCOTIC ADDICTS IN PRIVATE PRACTICE.
    Archives of internal medicine, 1964, Volume: 114

    Topics: Chlordiazepoxide; Chlorpromazine; Drug Therapy; Family Practice; General Practice; Glucose; Hospital

1964
AMBULATORY WITHDRAWAL TREATMENT OF HEROIN ADDICTS.
    New York state journal of medicine, 1964, Jul-15, Volume: 64

    Topics: Chloral Hydrate; Chlorpromazine; Drug Therapy; Glutethimide; Heroin; Humans; Meprobamate; Methylphen

1964
BARBITURATE USE IN NARCOTIC ADDICTS.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics

1964
[CEREBRAL ELECTRICAL ANOMALIES ACCOMPANYING THE ONSET OR CESSATION OF NEUROLEPTIC TREATMENTS].
    L'Encephale, 1964, Volume: 53

    Topics: Antipsychotic Agents; Barbiturates; Electroencephalography; Humans; Meprobamate; Metabolism; Schizop

1964
[EXPERIENCE WITH STEMBAMATE].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1964, Volume: 18

    Topics: Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Meprobamate; Neurotic Disorders

1964
FALSE ENDOCRINE TEST RESULTS DUE TO DRUGS.
    California medicine, 1964, Volume: 101

    Topics: 17-Ketosteroids; Aspirin; Diagnosis, Differential; Hypnotics and Sedatives; Hypopituitarism; Hypothy

1964
MEPROBAMATE WITHDRAWAL SYNDROME.
    Texas state journal of medicine, 1965, Volume: 61

    Topics: Humans; Meprobamate; Substance Withdrawal Syndrome; Substance-Related Disorders

1965
THE ROLE OF TRANQUILIZERS IN MEDICAL PRACTICE IN THE CONTROL OF ANXIETY. IMPORTANT AND RELEVANT ASPECTS OF TRANQUILIZER THERAPY.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Anxiety; Anxiety Disorders; Barbiturates; Biomedical Research; Chlordiazepoxide; Diazepam; Drug Ther

1964
[THE CONCEPT OF TOXICOMANIA].
    Belgisch tijdschrift voor geneeskunde, 1964, Dec-01, Volume: 20

    Topics: Alcoholism; Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Barbitura

1964
[TRANQUILIZERS AND PSYCHOTONICS].
    Hippokrates, 1965, Feb-15, Volume: 36

    Topics: Amphetamine; Amphetamines; Chlordiazepoxide; Diazepam; Drug Therapy; Humans; Meprobamate; Methamphet

1965
STUDIES ON ANTAGONISM OF MORPHINE MIOSIS BY NALORPHINE AS A DIAGNOSTIC TEST FOR NARCOTIC USAGE.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Atropa belladonna; Chlorpromazine; Diagnosis; Diagnostic Tests, Routine; Humans; Meprobamate; Miosis

1965
Withdrawal reactions from meprobamate, alone and combined with promazine: a controlled study.
    Psychopharmacologia, 1960, Jun-23, Volume: 1

    Topics: Behavior, Addictive; Meprobamate; Promazine; Research Design; Substance Withdrawal Syndrome; Substan

1960
Impairment due to intake of carisoprodol.
    Drug and alcohol dependence, 2004, Jun-11, Volume: 74, Issue:3

    Topics: Analysis of Variance; Automobile Driving; Carisoprodol; Chi-Square Distribution; Confidence Interval

2004
Carisoprodol use and abuse in Norway: a pharmacoepidemiological study.
    British journal of clinical pharmacology, 2007, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Carisoprodol; Drug Prescriptions; Female; Humans; Male; Meprobamate; Muscle Relax

2007
Diagnosis and management of depressant drug dependence.
    The American journal of psychiatry, 1967, Volume: 123, Issue:8

    Topics: Adult; Aged; Analgesics; Barbiturates; Chlordiazepoxide; Drug Tolerance; Female; Humans; Hypnotics a

1967
The use and abuse of hypnotics.
    Gerontologia clinica, 1967, Volume: 9, Issue:4

    Topics: Aged; Amobarbital; Antidepressive Agents; Antipyrine; Chloral Hydrate; Humans; Hypnotics and Sedativ

1967
An integrated approach to iatrogenic drug abuse in a closed delivery system.
    Military medicine, 1980, Volume: 145, Issue:1

    Topics: Adult; Aged; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Doxepin; Drug and Narcotic Control; Dr

1980
Clinical aspects of drug intoxication: barbiturates and a potpourri of other sedatives, hypnotics, and tranquilizers.
    Heart & lung : the journal of critical care, 1983, Volume: 12, Issue:2

    Topics: Adult; Barbiturates; Charcoal; Chloral Hydrate; Ethchlorvynol; Gastric Emptying; Glutethimide; Hemop

1983
Persistence of drug experience in rats formerly dependent on phenobarbital or meprobamate.
    Neuropharmacology, 1983, Volume: 22, Issue:7

    Topics: Animals; Body Temperature; Body Weight; Codeine; Humans; Male; Meprobamate; Phenobarbital; Rats; Rat

1983
Physical dependence on meprobamate after repeated oral administration in rats.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:6

    Topics: Administration, Oral; Animals; Body Temperature; Body Weight; Codeine; Humans; Male; Meprobamate; Ph

1983
Impaired brain functions due to diazepam and meprobamate abuse in a 53-year-old-male.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:8

    Topics: Cognition Disorders; Diazepam; Humans; Male; Memory Disorders; Meprobamate; Middle Aged; MMPI; Motor

1984
Toward a generic conception of alcoholism.
    The American journal of orthopsychiatry, 1981, Volume: 51, Issue:3

    Topics: Alcoholism; Barbiturates; Humans; Meprobamate; Phenothiazines; Substance-Related Disorders

1981
The present status of meprobamate ingestion. A five-year review of cases with serum concentrations and clinical findings.
    American journal of clinical pathology, 1981, Volume: 75, Issue:1

    Topics: Adolescent; Adult; Consciousness; Female; Half-Life; Humans; Male; Meprobamate; Middle Aged; Substan

1981
Meprobamate dependence secondary to carisoprodol (Soma) use.
    The American journal of drug and alcohol abuse, 1993, Volume: 19, Issue:1

    Topics: Adult; Biotransformation; Carisoprodol; Female; Humans; Meprobamate; Metabolic Clearance Rate; Neuro

1993
Management of the prescription-drug-dependent adult: case of meprobamate abuse and its treatment.
    Journal of geriatric psychiatry and neurology, 1996, Volume: 9, Issue:2

    Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Humans; Hypno

1996
Carisoprodol, meprobamate, and driving impairment.
    Journal of forensic sciences, 2000, Volume: 45, Issue:3

    Topics: Accidents, Traffic; Adult; Alcohol Drinking; Automobile Driving; Carisoprodol; Female; Forensic Medi

2000
[Study of flunitrazepam in a psychiatric practice].
    La Nouvelle presse medicale, 1979, Jul-11, Volume: 8, Issue:31

    Topics: Acepromazine; Anti-Anxiety Agents; Barbiturates; Clorazepate Dipotassium; Drug Combinations; Drug To

1979
Concomitant alcohol and drug abuse enhancing acetaminophen toxicity. Report of a case.
    The American journal of gastroenterology, 1978, Volume: 70, Issue:4

    Topics: Acetaminophen; Adult; Alcoholic Intoxication; Alcoholism; Chemical and Drug Induced Liver Injury; Fe

1978
Experience with hemoperfusion in drug abuse.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Adult; Barbiturates; Charcoal; Ethchlorvynol; Female; Glutethimide; Humans; Kidneys, Artificial; Mal

1976
Conditioned learning in young rats born of drug-addicted parents and raised on addictive drugs.
    Psychopharmacologia, 1975, Volume: 41, Issue:2

    Topics: Animals; Animals, Newborn; Avoidance Learning; Birth Weight; Body Weight; Conditioning, Psychologica

1975
Anxiety neurosis, depressive disorder and meprobamate addiction.
    The Western journal of medicine, 1975, Volume: 123, Issue:2

    Topics: Adjustment Disorders; Anxiety Disorders; Female; Humans; Meprobamate; Middle Aged; Substance-Related

1975
Conditioned avoidance behavior in pretrained rats intermittently treated with addictive drugs.
    Physiology & behavior, 1975, Volume: 15, Issue:3

    Topics: Amphetamine; Animals; Avoidance Learning; Body Weight; Conditioning, Operant; Dose-Response Relation

1975
Contemporary drugs of abuse.
    American family physician, 1986, Volume: 33, Issue:3

    Topics: Amphetamines; Anti-Anxiety Agents; Antipsychotic Agents; Barbiturates; Benzodiazepines; Caffeine; Co

1986
A retrospective study of drugged driving in Norway.
    Forensic science international, 1987, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Automobile Driving; Diazepam; Dronabinol; Ethanol; Fema

1987
[Drug addiction in the psychiatric hospital].
    Revue medicale de Liege, 1986, Jun-01, Volume: 41, Issue:11

    Topics: Barbiturates; Hospitals, Psychiatric; Humans; Meprobamate; Substance-Related Disorders

1986
Blood and tissue concentrations of drugs associated with fatalities.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Age Factors; Autopsy; Barbiturates; Brain Chemistry; Bronchopneumonia; Child; Chl

1974
[Drug dependence in rats: substitution test and sequential changes in body weight].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:5

    Topics: Animals; Body Weight; Codeine; Drug Therapy, Combination; Humans; Male; Meprobamate; Morphine; Morph

1974
Programmed self-administration of potentially addictive drugs in young rats and its effects on learning.
    Psychopharmacologia, 1974, Volume: 38, Issue:2

    Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Drug Tolerance; Ethanol; Extinction, Psy

1974
A simple method for evaluating physical dependence liability in rats.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Aminopyrine; Animals; Azepines; Body Weight; Codeine; Cyproheptadine; Dextropropoxyphene; Humans; Ma

1973
Brain and eye abnormalities. Possible sequelae to prenatal use of multiple drugs including LSD.
    American journal of diseases of children (1960), 1972, Volume: 123, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Amphetamine; Brain; Cannabis; Eye Abnormalities; Female; Humans;

1972
Dependence liability of several sedative-hypnotic agents evaluated in monkeys.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:2

    Topics: Animals; Anthracenes; Barbiturates; Benzazepines; Catheterization; Chlordiazepoxide; Chloroform; Chl

1973
[Procedure for assessing anxiety; therapeutic results].
    La Revue du praticien, 1972, Apr-21, Volume: 22, Issue:12

    Topics: Adjustment Disorders; Alcoholism; Antidepressive Agents; Anxiety; Bipolar Disorder; Depression; Diag

1972
Some behavioral and EEG effects of a new analgesic agent (viminol) in comparison with morphine in rats.
    European journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Benzyl Compounds; Butylamines; Conditioning, Operant; Dose-Re

1973
Letter: Prescribing hypnotic and anti-anxiety drugs.
    Annals of internal medicine, 1973, Volume: 79, Issue:3

    Topics: Chlordiazepoxide; Diazepam; Drug Prescriptions; Humans; Hypnotics and Sedatives; Meprobamate; Pentob

1973
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chr

1974
An attempt to detect drug abuse.
    Activitas nervosa superior, 1971, Volume: 13, Issue:3

    Topics: Czechoslovakia; Digoxin; Drug Prescriptions; Electronic Data Processing; Humans; Hydrochlorothiazide

1971
Sociological and economic aspects of drug dependence in India.
    The International journal of the addictions, 1972, Volume: 7, Issue:1

    Topics: Alcoholism; Barbiturates; Cannabis; Cross-Cultural Comparison; Humans; Income; India; Meperidine; Me

1972
[Drug dependence and current status of drug abuse].
    Nihon Ishikai zasshi. Journal of the Japan Medical Association, 1972, Feb-15, Volume: 67, Issue:2

    Topics: Chlordiazepoxide; Diazepam; Humans; Japan; Meprobamate; Quinazolines; Substance-Related Disorders

1972
Tranquilizer control.
    JAMA, 1972, Sep-25, Volume: 221, Issue:13

    Topics: Age Factors; Attitude of Health Personnel; Diazepam; Drug and Narcotic Control; Drug Utilization; Hu

1972
[Alcohol and drugs in blood and urine. 100 consecutive cases of persons arrested by the Stockholm police].
    Lakartidningen, 1971, Jun-21, Volume: 68, Issue:30

    Topics: Adolescent; Adult; Alcoholic Intoxication; Amines; Appetite Depressants; Barbiturates; Chromatograph

1971
Chlormethiazole treatment of abstinence symptoms after drug withdrawal. Preliminary reports. 3.
    Acta psychiatrica Scandinavica. Supplementum, 1966, Volume: 192

    Topics: Alcoholism; Barbiturates; Chlormethiazole; Humans; Hypnotics and Sedatives; Male; Meprobamate; Subst

1966
[Pharmacokinetics of meprobamate in chronic liver diseases and drug addiction].
    Klinische Wochenschrift, 1969, Jan-15, Volume: 47, Issue:2

    Topics: Adult; Aged; Fatty Liver; Female; Hepatitis; Humans; Kinetics; Liver Cirrhosis; Male; Meprobamate; M

1969
[A case of glutethimide and meprobamate dependance with delirium as a drug withdrawal symptom].
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Aged; Delirium; Female; Glutethimide; Humans; Meprobamate; Substance Withdrawal Syndrome; Substance-

1970
A new method for treatment of barbiturate dependence.
    JAMA, 1970, Jul-13, Volume: 213, Issue:2

    Topics: Barbiturates; Chlordiazepoxide; Diazepam; Heroin; Humans; Meprobamate; Pentobarbital; Phenobarbital;

1970
[Drug dependence and addiction among patients of the Vienna Psychiatric-Neurological University Hospital with special reference to psychotropic drugs].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Analgesics; Antidepressive Agents; Antitussive Agents; Austria; Barbiturates; Cannabis; Chlordiazepo

1970
[Drug dependence--a clinical and theoretical evaluation].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1971, Aug-10, Volume: 91, Issue:21

    Topics: Adolescent; Adult; Barbiturates; Cannabis; Diazepam; Dibenzazepines; Humans; Meprobamate; Personalit

1971
A system of screening for the presence of a number of common drugs.
    Journal of clinical pathology, 1967, Volume: 20, Issue:2

    Topics: Barbiturates; Blood Chemical Analysis; Bromides; Butyrates; Carbon Monoxide; Chromatography, Thin La

1967
Recent patterns of addiction in Czechoslovakia.
    The British journal of psychiatry : the journal of mental science, 1968, Volume: 114, Issue:508

    Topics: Adult; Analgesics; Antipyrine; Aspirin; Barbiturates; Bronchodilator Agents; Caffeine; Czechoslovaki

1968
Self administration of monor tranquilizers as a functiion of conditioning.
    Psychopharmacologia, 1968, Volume: 13, Issue:1

    Topics: Animals; Chlordiazepoxide; Conditioning, Classical; Conditioning, Psychological; Discrimination, Psy

1968
[On a syndrome due to withdrawl from meprobamates].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1968, Jun-30, Volume: 92, Issue:3

    Topics: Adult; Hallucinations; Humans; Male; Meprobamate; Seizures; Substance Withdrawal Syndrome; Substance

1968
[On a syndrome due to withdrawal from meprobamates].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1968, Jun-30, Volume: 92, Issue:3

    Topics: Adult; Hallucinations; Humans; Male; Meprobamate; Seizures; Substance Withdrawal Syndrome; Substance

1968
Experiences from an out-patient department for drug addicts in Göteborg.
    Acta psychiatrica Scandinavica, 1968, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Age Factors; Barbiturates; Cannabis; Cocaine; Community Mental Health Services; F

1968
[Compulsive use of and physical dependence on miprobamate. Apropos of a consumer of 24 grams daily].
    Revista de neuro-psiquiatria, 1968, Volume: 31, Issue:3

    Topics: Adult; Compulsive Behavior; Humans; Male; Meprobamate; Substance-Related Disorders

1968
The addictive process in unusual addictions: a further elaboration of etiology.
    The American journal of psychiatry, 1969, Volume: 125, Issue:9

    Topics: Body Image; Defense Mechanisms; Depression; Ego; Fantasy; Female; Frustration; Habits; Humans; Male;

1969
[Therapy of anxiety, mental anguish and sleeplessness. 4. Drug abuse and accidents].
    Lakartidningen, 1969, Mar-17, Volume: 66

    Topics: Accidents, Traffic; Barbiturates; Chlordiazepoxide; Chlormethiazole; Diazepam; Drug Synergism; Ethan

1969
[Therapy of anxiety, mental anguish and sleeplessness. 5. Abuse of diazepam?].
    Lakartidningen, 1969, Mar-17, Volume: 66

    Topics: Chlordiazepoxide; Diazepam; Humans; Meprobamate; Substance Withdrawal Syndrome; Substance-Related Di

1969
Meprobamate.
    The Medical letter on drugs and therapeutics, 1965, Apr-23, Volume: 7, Issue:9

    Topics: Humans; Meprobamate; Substance-Related Disorders

1965
[Addiction to and abuse of tranquilizers].
    Wiener medizinische Wochenschrift (1946), 1965, Nov-27, Volume: 115, Issue:48

    Topics: Chlordiazepoxide; Diazepam; Humans; Meprobamate; Substance-Related Disorders; Tranquilizing Agents

1965
[Delirious condition of excitation after meprobamate intoxication--intoxication effect or inanition delirium?].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1966, Volume: 18, Issue:12

    Topics: Delirium; Humans; Male; Meprobamate; Starvation; Substance-Related Disorders

1966
[Drug misuse and addiction].
    Zeitschrift fur arztliche Fortbildung, 1966, Jul-01, Volume: 60, Issue:13

    Topics: Amphetamine; Analgesics; Cocaine; Female; Hallucinogens; Humans; Hypnotics and Sedatives; Male; Mepr

1966