meprobamate has been researched along with Bile Duct Obstruction in 2 studies
Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The metabolism of meprobamate, pentobarbital and tolbutamide was assessed in subjects with intrahepatic recurrent cholestasis (3), cholestatic hepatitis (6), extrahepatic biliary obstruction (7) and normal controls (16)." | 3.65 | Alteration of drug metabolism during cholestasis in man. ( Carulli, N; Ferrari, A; Gallo, M; Manenti, F; Ponz de Leon, M; Salvioli, G, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carulli, N | 1 |
| Manenti, F | 1 |
| Ponz de Leon, M | 1 |
| Ferrari, A | 1 |
| Salvioli, G | 1 |
| Gallo, M | 1 |
| Dold, U | 1 |
| Held, H | 1 |
| Zysno, E | 1 |
2 other studies available for meprobamate and Bile Duct Obstruction
| Article | Year |
|---|---|
Alteration of drug metabolism during cholestasis in man.
Topics: Adolescent; Adult; Aged; Cholestasis; Female; Half-Life; Hepatitis; Humans; Liver; Male; Meprobamate | 1975 |
[On the effect and excretion of sedative drugs in patients with liver diseases].
Topics: Cholestasis; Electroencephalography; Humans; Injections, Intravenous; Liver Diseases; Meprobamate | 1965 |