meprobamate has been researched along with Agranulocytosis in 7 studies
Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 52 year old man admitted to hospital in a toxic state, was found to have agranulocytosis, which recovered when an analgesic containing meprobamate was stopped." | 7.67 | Reversible agranulocytosis due to meprobamate. ( Meecham, J; Ward, S, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ZWEIFLER, AJ | 1 |
| CROMIE, BW | 1 |
| Ward, S | 1 |
| Meecham, J | 1 |
| Gracheva, NM | 1 |
| Rose, MS | 1 |
| Leahy, MF | 1 |
| Stevens, A | 1 |
| Black, PJ | 1 |
| Barkhan, P | 1 |
| Greenblatt, DJ | 1 |
| Shader, RI | 1 |
| Nitzschner, H | 1 |
1 trial available for meprobamate and Agranulocytosis
| Article | Year |
|---|---|
Meprobamate: a study of irrational drug use.
Topics: Agranulocytosis; Anemia, Aplastic; Anxiety; Chlordiazepoxide; Diazepam; Humans; Meprobamate; Neuroti | 1971 |
6 other studies available for meprobamate and Agranulocytosis
| Article | Year |
|---|---|
Agranulocytosis and jaundice during therapy with meprobamate and promazine.
Topics: Agranulocytosis; Humans; Jaundice; Meprobamate; Promazine | 1960 |
MEPROBAMATE AND APLASTIC ANAEMIA.
Topics: Agranulocytosis; Anemia; Anemia, Aplastic; Meprobamate; Toxicology | 1964 |
Reversible agranulocytosis due to meprobamate.
Topics: Agranulocytosis; Humans; Male; Meprobamate; Middle Aged | 1986 |
[Medicamentous agranulocytosis as a manifestation of drug induced disease].
Topics: Adult; Agranulocytosis; Aminopyrine; Aspirin; Chloramphenicol; Drug-Related Side Effects and Adverse | 1974 |
The bone marrow during recovery from drug induced agranulocytosis.
Topics: Agranulocytosis; Analgesics; Aspirin; Azepines; Bone Marrow; Bone Marrow Cells; Bone Marrow Examinat | 1972 |
[Agranulocytosis as a result of an allergic cross reaction of procaine penicillin and meprobamate].
Topics: Agranulocytosis; Drug Hypersensitivity; Female; Humans; Meprobamate; Middle Aged; Penicillin G Proca | 1967 |