meprobamate has been researched along with Absence Seizure Disorder in 4 studies
Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
| Excerpt | Relevance | Reference |
|---|---|---|
| " PTZ test was influenced by meprobamate in a fairly low dosage (ED50 66 mg/kg), but for felbamate no clearly dose-related effect could be shown up to 150 mg/kg." | 1.30 | Felbamate and meprobamate: a comparison of their anticonvulsant properties. ( Bartels, I; Frey, HH, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MICHELETTI, V | 1 |
| INGA, EF | 1 |
| SCHOLL, ML | 1 |
| Frey, HH | 1 |
| Bartels, I | 1 |
| Auckland, NL | 1 |
4 other studies available for meprobamate and Absence Seizure Disorder
| Article | Year |
|---|---|
[Treatment of minor epilepsy with meprobamate].
Topics: Epilepsy; Epilepsy, Absence; Meprobamate | 1957 |
CURRENT CONCEPTS IN THERAPY: TREATMENT OF SEIZURE DISORDERS (EPILEPSY). (CONCLUDED FROM DECEMBER 12).
Topics: Acetazolamide; Anticonvulsants; Child; Chlordiazepoxide; Dextroamphetamine; Epilepsy; Epilepsy, Abse | 1963 |
Felbamate and meprobamate: a comparison of their anticonvulsant properties.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy, Absence; Felbamate; Female | 1997 |
Drugs for petit mal.
Topics: Acetazolamide; Amphetamine; Anticonvulsants; Barbiturates; Child; Child, Preschool; Chlordiazepoxide | 1965 |