mepivacaine has been researched along with Muscle Contraction in 21 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cold saline-induced paresthesiae in the hand or forearm were obtained in 19 patients (95%) during one of four attempts allowed, and in 15 patients (75%) on the first attempt." | 2.68 | Axillary brachial plexus anesthesia: electrical versus cold saline stimulation. ( Alvarez, J; Bárcena, M; Rodríguez, J, 1996) |
| "Mepivacaine is an aminoamide local anesthetic that produces vasoconstriction in vivo and in vitro." | 1.40 | Mepivacaine-induced contraction involves increased calcium sensitization mediated via Rho kinase and protein kinase C in endothelium-denuded rat aorta. ( Choi, MJ; Chung, YK; Kwon, SC; Lee, HK; Ok, SH; Shin, IW; Sohn, JT; Yeol Han, J; Yu, J, 2014) |
| "Mepivacaine is an aminoamide local anesthetic with an intermediate duration that intrinsically produces vasoconstriction both in vivo and in vitro." | 1.39 | Mepivacaine-induced contraction involves phosphorylation of extracellular signal-regulated kinase through activation of the lipoxygenase pathway in isolated rat aortic smooth muscle. ( Bae, SI; Choi, MJ; Chung, YK; Eun, SY; Kang, S; Kim, HJ; Lee, HK; Lee, HM; Lee, SH; Ok, SH; Shin, IW; Sohn, JT; Sung, HJ, 2013) |
| "Mepivacaine is an aminoamide-linked local anesthetic with an intermediate duration that intrinsically produces vasoconstriction both in vivo and in vitro." | 1.38 | Mepivacaine-induced contraction is attenuated by endothelial nitric oxide release in isolated rat aorta. ( Chang, KC; Choi, MJ; Chung, YK; Hwang, IJ; Kim, HS; Lee, HK; Lee, SH; Ok, SH; Park, KE; Shin, IW; Sohn, JT; Sung, HJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (71.43) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, HM | 1 |
| Ok, SH | 3 |
| Sung, HJ | 2 |
| Eun, SY | 1 |
| Kim, HJ | 1 |
| Lee, SH | 2 |
| Kang, S | 1 |
| Shin, IW | 3 |
| Lee, HK | 3 |
| Chung, YK | 3 |
| Choi, MJ | 3 |
| Bae, SI | 1 |
| Sohn, JT | 3 |
| Kwon, SC | 1 |
| Yeol Han, J | 1 |
| Yu, J | 1 |
| Hwang, IJ | 1 |
| Kim, HS | 1 |
| Chang, KC | 1 |
| Park, KE | 1 |
| Bakke, M | 1 |
| Møller, E | 1 |
| Rasmussen, OC | 1 |
| Sharrock, NE | 1 |
| Hotchkiss, R | 1 |
| Ennis, WJ | 1 |
| Weiland, A | 1 |
| Rodríguez, J | 1 |
| Bárcena, M | 1 |
| Alvarez, J | 1 |
| Akata, T | 1 |
| Murakami, J | 1 |
| Yoshinaga, A | 1 |
| de Boever, J | 1 |
| McCall, WD | 1 |
| Holden, S | 1 |
| Ash, MM | 1 |
| Lograno, MD | 1 |
| Siro-Brigiani, G | 1 |
| Cortese, I | 1 |
| Cibils, LA | 1 |
| Struthers, NW | 1 |
| Sjövall, B | 1 |
| Berkowitz, A | 1 |
| Rosenberg, H | 1 |
| Aberg, G | 3 |
| Andersson, R | 2 |
| Welin-Fogelberg, I | 1 |
| Gennser, G | 1 |
| Jóhannsson, M | 1 |
| Nilsson, E | 1 |
| Wahlström, B | 1 |
| Freundlich, JJ | 1 |
| Wingate, MB | 1 |
| Brotanek, V | 1 |
| Vasicka, A | 1 |
| Santiago, A | 1 |
| Brotanek, JD | 1 |
| De Marées, H | 1 |
| Sewing, KF | 1 |
| Lembeck, F | 1 |
| Barbey, K | 1 |
| Rogers, RE | 1 |
1 trial available for mepivacaine and Muscle Contraction
| Article | Year |
|---|---|
Axillary brachial plexus anesthesia: electrical versus cold saline stimulation.
Topics: Anesthetics, Local; Axilla; Brachial Plexus; Buffers; Cold Temperature; Electric Stimulation; Female | 1996 |
20 other studies available for mepivacaine and Muscle Contraction
| Article | Year |
|---|---|
Mepivacaine-induced contraction involves phosphorylation of extracellular signal-regulated kinase through activation of the lipoxygenase pathway in isolated rat aortic smooth muscle.
Topics: Animals; Aorta, Thoracic; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cells, Cultured; Cyclooxyge | 2013 |
Mepivacaine-induced contraction involves increased calcium sensitization mediated via Rho kinase and protein kinase C in endothelium-denuded rat aorta.
Topics: Anesthetics, Local; Animals; Aorta, Thoracic; Calcium; Endothelium, Vascular; Male; Mepivacaine; Mus | 2014 |
Mepivacaine-induced contraction is attenuated by endothelial nitric oxide release in isolated rat aorta.
Topics: Anesthetics, Local; Animals; Aorta; Calcium; Calcium Channels; Cells, Cultured; Cyclic GMP; Endothel | 2012 |
Effect of intramuscular local anaesthetics on maximal voluntary activity in human anterior temporal muscles.
Topics: Adult; Anesthesia, Local; Humans; Injections, Intramuscular; Male; Masseter Muscle; Masticatory Musc | 1980 |
Brachial plexus surgery through the infraclavicular approach using an interscalene block.
Topics: Adult; Arm; Brachial Plexus; Bupivacaine; Clavicle; Electric Stimulation; Female; Humans; Mepivacain | 1996 |
Life-threatening haemorrhage following obturator artery injury during transurethral bladder surgery: a sequel of an unsuccessful obturator nerve block.
Topics: Aged; Anesthetics, Local; Arteries; Blood Loss, Surgical; Electric Stimulation; Electrosurgery; Huma | 1999 |
Functional occlusal forces under anesthesia.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Dental Stress Analysis; Electromyography; Female; Huma | 1978 |
[Effects of lidocaine, mepivacaine and prilocaine on the detrusor muscle of the rat urinary bladder].
Topics: Anesthetics, Local; Animals; Female; Lidocaine; Male; Mepivacaine; Muscle Contraction; Muscles; Pril | 1979 |
Response of human uterine arteries to local anesthetics.
Topics: Anesthesia, Obstetrical; Anesthetics, Local; Arteries; Dose-Response Relationship, Drug; Female; Hum | 1976 |
Modifications of ureteric peristalsis by local anaesthetic. An experimental study in dogs.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Female; Lidocaine; Mepivacaine; Muscle Contraction; | 1976 |
The effect of some local anaesthetics upon the electrical and mechanical activity of respiratory muscles in cats during pentobarbital anaesthesia.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carbon Dioxide; Cats; Depression, Chemical; Diaphragm; Fem | 1975 |
Femoral block with mepivacaine for muscle biopsy in malignant hyperthermia patients.
Topics: Adolescent; Adult; Aged; Biopsy; Child; Child, Preschool; Femoral Nerve; Humans; Malignant Hyperther | 1985 |
Studies on mechanical actions of mepivacaine (Carbocaine) and its optically active isomers on isolated smooth muscle: role of Ca ++ and cyclic AMP.
Topics: Animals; Barium; Calcium; Calcium Isotopes; Colon; Cyclic AMP; Female; Guinea Pigs; Histamine; Human | 1972 |
Inhibition of tone in the taenia of the guinea pig caecum.
Topics: Acetylcholine; Animals; Cecum; Electric Stimulation; Ganglionic Blockers; Guinea Pigs; In Vitro Tech | 1969 |
The influence of contraction frequency and of a local anesthetic (Mepivacaine) on human fetal myocardium.
Topics: Action Potentials; Depression, Chemical; Dextrans; Dose-Response Relationship, Drug; Female; Fetus; | 1972 |
Mechanical and electrophysiological effects of some local anaesthetic agents and their isomers on the rat portal vein.
Topics: Action Potentials; Anesthetics, Local; Animals; Bupivacaine; In Vitro Techniques; Isomerism; Male; M | 1972 |
An evaluation of an external electromyographic system for recording uterine contractions during labor.
Topics: Adolescent; Adult; Anesthesia, Epidural; Electromyography; Evaluation Studies as Topic; Female; Feta | 1973 |
The influence of epidural anesthesia on uterine blood flow.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Pressure; Female; Fetal Heart; Heart Rate; Huma | 1973 |
[The effect of suxamethonium on extraocular muscles and intraocular pressure in cats].
Topics: Animals; Bis-Trimethylammonium Compounds; Cats; Female; Intraocular Pressure; Male; Manometry; Mepiv | 1969 |
Fetal bradycardia associated with paracervical block anesthesia in labor.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Female; Fetal Heart; Humans; Infant, N | 1970 |