mepivacaine has been researched along with Methemoglobinemia in 5 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mepivacaine was selected for routine use since prilocaine induced methaemoglobinaemia." | 2.67 | Comparison of two local anaesthetics in transvaginal ultrasound-guided oocyte retrieval. ( Camus, M; De Munck, L; Devroey, P; Erard, P; Gepts, E; Godoy, H; Van Steirteghem, AC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Godoy, H | 1 |
| Erard, P | 1 |
| De Munck, L | 1 |
| Camus, M | 1 |
| Gepts, E | 1 |
| Van Steirteghem, AC | 1 |
| Devroey, P | 1 |
| Eifert, B | 1 |
| Hahn, R | 1 |
| Maier, B | 1 |
| Konrad, F | 1 |
| Georgieff, M | 1 |
| Epstein, BS | 1 |
| Coakley, CS | 1 |
| Barter, RH | 1 |
| Chamberlain, G | 1 |
| Usubiaga, JE | 1 |
| La Iuppa, M | 1 |
| Moya, F | 1 |
| Wikinski, JA | 1 |
| Velazco, R | 1 |
| Poppers, PJ | 1 |
| Vosburgh, GJ | 1 |
| Finster, M | 1 |
2 trials available for mepivacaine and Methemoglobinemia
| Article | Year |
|---|---|
Comparison of two local anaesthetics in transvaginal ultrasound-guided oocyte retrieval.
Topics: Adult; Female; Fertilization in Vitro; Humans; Mepivacaine; Methemoglobinemia; Oocytes; Pain Measure | 1993 |
[Combined "3-in-1"/sciatic nerve block. Block effectiveness, serum level and side effects using 700 mg mepivacaine 1% without and with adrenaline and prilocaine 1%].
Topics: Adult; Anesthetics, Local; Ankle; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine | 1996 |
3 other studies available for mepivacaine and Methemoglobinemia
| Article | Year |
|---|---|
New developments in epidural anesthesia for obstetrics.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Epinephrine; Female; Fetus; Humans; Lidocaine; Mepivaca | 1970 |
Passage of procaine hydrochloride and para-aminobenzoic acid across the human placenta.
Topics: Adjuvants, Anesthesia; Aminobenzoates; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, | 1968 |
Methemoglobinemia following epidural analgesia during labor. A case report and literature review.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Female; Glucose; Humans; Lidocaine; | 1966 |