Page last updated: 2024-10-30

mepivacaine and Jaundice, Neonatal

mepivacaine has been researched along with Jaundice, Neonatal in 1 studies

Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.

Jaundice, Neonatal: Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Our results suggest that the neonatal jaundice associated with maternal anesthesia, especially bupivacaine, may be related to the observations that these agents cross the placenta, bind to the red cell membrane and reduce its filterability, resulting in shortened red cell survival."1.27Bupivacaine alters red blood cell properties: a possible explanation for neonatal jaundice associated with maternal anesthesia. ( Clark, DA; Landaw, SA, 1985)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clark, DA1
Landaw, SA1

Other Studies

1 other study available for mepivacaine and Jaundice, Neonatal

ArticleYear
Bupivacaine alters red blood cell properties: a possible explanation for neonatal jaundice associated with maternal anesthesia.
    Pediatric research, 1985, Volume: 19, Issue:4

    Topics: Adult; Anesthesia, Epidural; Animals; Bupivacaine; Cell Survival; Erythrocyte Deformability; Erythro

1985