mepivacaine has been researched along with Hypesthesia in 3 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this prospective, randomized, double-blind study was to compare injection pain and postinjection pain of 2% lidocaine with 1:100,000 epinephrine and 3% mepivacaine using the computer-assisted Wand Plus injection system to administer the palatal-anterior superior alveolar (P-ASA) injection." | 9.11 | Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine. ( Beck, M; Burns, Y; Nusstein, J; Reader, A; Weaver, J, 2004) |
| "The purpose of this prospective, randomized, double-blind study was to compare injection pain and postinjection pain of 2% lidocaine with 1:100,000 epinephrine and 3% mepivacaine using the computer-assisted Wand Plus injection system to administer the palatal-anterior superior alveolar (P-ASA) injection." | 5.11 | Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine. ( Beck, M; Burns, Y; Nusstein, J; Reader, A; Weaver, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nusstein, J | 1 |
| Burns, Y | 1 |
| Reader, A | 2 |
| Beck, M | 2 |
| Weaver, J | 1 |
| McLean, C | 1 |
| Meryers, WJ | 1 |
| Okutomi, T | 1 |
| Hoka, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573] | Phase 1 | 31 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
| A Prospective, Randomized, Double-blind Study of the Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Inferior Alveolar Nerve Blocks.[NCT01574807] | Phase 4 | 100 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| Inferior Alveolar Nerve Block: a Novel Intraoral Technique Depends on Extraoral Landmarks[NCT04093713] | 65 participants (Anticipated) | Interventional | 2019-09-14 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
An electric pulp tester will be used to test the lower jaw teeth (molars, premolars, and incisors) for anesthesia (numbness) in 4-minute time cycles for 60 minutes. Measurements of less than 80 on the EPT is considered not numb (anesthesia failure). Readings of 80 equate to anesthetic success. (NCT01574807)
Timeframe: 60 minutes per injection sequence.
| Intervention | Participants (Count of Participants) |
|---|---|
| Mepivacaine + Lidocaine | 44 |
| Lidocaine + Lidocaine | 40 |
3 trials available for mepivacaine and Hypesthesia
| Article | Year |
|---|---|
Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Epinephrine; | 2004 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
Epidural saline solution prior to local anaesthetic produces differential nerve block.
Topics: Abdomen; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Local; Cold Te | 1998 |