Page last updated: 2024-10-30

mepivacaine and Glaucoma

mepivacaine has been researched along with Glaucoma in 11 studies

Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
" A prospective, consecutive study concerning cyclocryotherapy in advanced glaucoma was started using subconjunctival anaesthesia with 5 % cocaine or, alternatively, 2 % mepivacaine in 25 eyes of 25 patients in each group."9.11[Subconjunctival anaesthesia using cocaine or mepivacaine for cyclocryotherapy in advanced glaucoma]. ( Mielke, J; Schlote, T, 2004)
"To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery."9.11Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005)
"To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery."5.11Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sauder, G1
Jonas, JB1
CASTREN, JA1
HILL, HF1
LOPEZ, E1
HILL, K1
Mielke, J1
Schlote, T1
Rebolleda, G1
Muñoz-Negrete, FJ1
Benatar, J1
Corcostegui, J1
Alonso, N1
Parrish, RK1
Spaeth, GL1
Poryzees, EM1
Hargens, CW1
Azuara-Blanco, A1
Moster, MR1
Marr, BP1
Bellucci, R1
Morselli, S1
Pucci, V1
Babighian, S1
Thorburn, W1
Thorn-Alquist, AM1
Edström, H1
Laaka, V1
Nikki, P1
Tarkkanen, A1
Friedrich, H1

Trials

7 trials available for mepivacaine and Glaucoma

ArticleYear
Topical anesthesia for penetrating trabeculectomy.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2002, Volume: 240, Issue:9

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Female; Glaucoma; Human

2002
[Subconjunctival anaesthesia using cocaine or mepivacaine for cyclocryotherapy in advanced glaucoma].
    Klinische Monatsblatter fur Augenheilkunde, 2004, Volume: 221, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Ciliary Body; Cocaine; Cryosu

2004
Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage.
    Acta ophthalmologica Scandinavica, 2005, Volume: 83, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Female; Gels; Glauc

2005
Evaluation of local anesthesia agents using a new force-sensitive lid speculum.
    Ophthalmic surgery, 1983, Volume: 14, Issue:7

    Topics: Anesthetics, Local; Bupivacaine; Facial Nerve; Glaucoma; Humans; Lidocaine; Mepivacaine; Random Allo

1983
Subconjunctival versus peribulbar anesthesia in trabeculectomy: a prospective, randomized study.
    Ophthalmic surgery and lasers, 1997, Volume: 28, Issue:11

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Conjunctiva; Drug Combinations; Eye Moveme

1997
Etidocaine in retrobulbar anaesthesia. A comparison with mepivacaine.
    Acta ophthalmologica, 1976, Volume: 54, Issue:5

    Topics: Acetanilides; Adult; Aged; Anesthesia, Local; Cataract Extraction; Clinical Trials as Topic; Drug Ev

1976
Comparison of bupivacaine with and without adrenalin and mepivacaine with adrenalin in intraocular surgery.
    Acta ophthalmologica, 1972, Volume: 50, Issue:2

    Topics: Aged; Anesthetics, Local; Bupivacaine; Cataract Extraction; Drug Combinations; Epinephrine; Female;

1972

Other Studies

4 other studies available for mepivacaine and Glaucoma

ArticleYear
A CLINICAL EVALUATION OF MEPIVACAINE (CARBOCAIN) IN OCULAR SURGERY).
    Acta ophthalmologica, 1963, Volume: 41

    Topics: Cataract Extraction; Corneal Transplantation; Epinephrine; Glaucoma; Humans; Lidocaine; Mepivacaine;

1963
EFFECT OF RETROBULBAR ANESTHESIA UPON INTRAOCULAR PRESSURE. PRELIMINARY REPORT ON ITS IMPORTANCE IN CATARACT SURGERY.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1963, Volume: 70

    Topics: Anesthesia; Anesthesia, Local; Cataract; Cataract Extraction; Glaucoma; Humans; Injections; Intraocu

1963
Sub-Tenon's anesthesia for combined cataract and glaucoma surgery.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Anterior Eye Segment; Cataract; Follow-Up Studies; Glaucoma;

1999
[On the use of Scandicain in eye surgery].
    Klinische Monatsblatter fur Augenheilkunde, 1967, Volume: 150, Issue:5

    Topics: Anesthetics, Local; Eye Diseases; Glaucoma; Humans; Intraocular Pressure; Mepivacaine; Vasoconstrict

1967