Page last updated: 2024-10-30

mepivacaine and Facial Pain

mepivacaine has been researched along with Facial Pain in 10 studies

Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.

Facial Pain: Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

Research Excerpts

ExcerptRelevanceReference
"Anecdotally, orofacial pain patients sometimes report that the painful face area feels "swollen."1.42Painful stimulation and transient blocking of nerve transduction due to local anesthesia evoke perceptual distortions of the face in healthy volunteers. ( Baad-Hansen, L; Castrillon, E; Dagsdóttir, L; Jensen, TS; Roepstorff, A; Skyt, I; Svensson, P; Vase, L, 2015)
"Patients suffering from persistent orofacial pain may sporadically report that the painful area feels "swollen" or "differently," a phenomenon that may be conceptualized as a perceptual distortion because there are no clinical signs of swelling present."1.42Experimental orofacial pain and sensory deprivation lead to perceptual distortion of the face in healthy volunteers. ( Baad-Hansen, L; Castrillon, E; Dagsdóttir, LK; Skyt, I; Svensson, P; Vase, L, 2015)
"The study included data sets of annual sales of local anesthetics (from 1995 through 2007), 292 reports to the Danish Medicines Agency, Copenhagen, Denmark, of adverse reactions to local anesthetic drugs, and a clinical sample of 115 patients with NSD associated with local anesthetics."1.37Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity? ( Ersbøll, BK; Hillerup, S; Jensen, RH, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Yang, S1
Exposto, FG1
Mahmoodi, S1
Svensson, P4
Patini, R1
Staderini, E1
Cantiani, M1
Camodeca, A1
Guglielmi, F1
Gallenzi, P1
Skyt, I2
Dagsdóttir, L1
Vase, L2
Baad-Hansen, L2
Castrillon, E2
Roepstorff, A1
Jensen, TS1
Dagsdóttir, LK1
Hillerup, S1
Jensen, RH1
Ersbøll, BK1
Refai, H1
Altahhan, O1
Elsharkawy, R1
Mascia, P1
Brown, BR1
Friedman, S1
Wang, K1
Arendt-Nielsen, L1
Jensen, T1
McMahon, RE1
Adams, W1
Spolnik, KJ1
Montebugnoli, L1
Borea, G1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Two Local Anaesthesia Techniques on the Paediatric Patient's Recovery After Dental Treatment in General Anaesthesia[NCT04156334]120 participants (Actual)Interventional2020-02-25Completed
Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?[NCT03443726]120 participants (Actual)Interventional2017-06-10Completed
Assessment of Botulinum Toxin Injection for Treatment of Temporomandibular Joint Dislocation: Double-blind, Randomized, Placebo Controlled Trail Assessment of Botulinum Toxin Injection for Treatment of Temporomandibular Joint Dislocation[NCT05863286]28 participants (Anticipated)Interventional2022-12-30Recruiting
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection: A Randomised Clinical Trial of Efficacy[NCT01706172]Phase 2/Phase 342 participants (Actual)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for mepivacaine and Facial Pain

ArticleYear
Diagnostic anesthesia for referred trigeminal pain: Part 2.
    Compendium (Newtown, Pa.), 1992, Volume: 13, Issue:11

    Topics: Anesthesia, Dental; Anesthesia, Local; Facial Pain; Humans; Mepivacaine; Nerve Block

1992

Trials

3 trials available for mepivacaine and Facial Pain

ArticleYear
Mechanical sensitivity changes in pericranial muscles after local anesthesia and experimentally induced pain in the temporalis tendon: Implications for headache and facial pain.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:11-12

    Topics: Anesthesia, Local; Anesthetics, Local; Facial Pain; Headache; Humans; Mepivacaine; Pain Measurement;

2022
Dental anaesthesia for children - effects of a computer-controlled delivery system on pain and heart rate: a randomised clinical trial.
    The British journal of oral & maxillofacial surgery, 2018, Volume: 56, Issue:8

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Child; Child, Preschool; Dental Anxiety;

2018
The efficacy of dextrose prolotherapy for temporomandibular joint hypermobility: a preliminary prospective, randomized, double-blind, placebo-controlled clinical trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:12

    Topics: Adult; Anesthetics, Local; Arthralgia; Cell Proliferation; Chi-Square Distribution; Double-Blind Met

2011
The efficacy of dextrose prolotherapy for temporomandibular joint hypermobility: a preliminary prospective, randomized, double-blind, placebo-controlled clinical trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:12

    Topics: Adult; Anesthetics, Local; Arthralgia; Cell Proliferation; Chi-Square Distribution; Double-Blind Met

2011
The efficacy of dextrose prolotherapy for temporomandibular joint hypermobility: a preliminary prospective, randomized, double-blind, placebo-controlled clinical trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:12

    Topics: Adult; Anesthetics, Local; Arthralgia; Cell Proliferation; Chi-Square Distribution; Double-Blind Met

2011
The efficacy of dextrose prolotherapy for temporomandibular joint hypermobility: a preliminary prospective, randomized, double-blind, placebo-controlled clinical trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:12

    Topics: Adult; Anesthetics, Local; Arthralgia; Cell Proliferation; Chi-Square Distribution; Double-Blind Met

2011

Other Studies

6 other studies available for mepivacaine and Facial Pain

ArticleYear
Painful stimulation and transient blocking of nerve transduction due to local anesthesia evoke perceptual distortions of the face in healthy volunteers.
    The journal of pain, 2015, Volume: 16, Issue:4

    Topics: Anesthetics, Local; Face; Facial Pain; Female; Humans; Male; Mandibular Nerve; Maxillary Nerve; Mepi

2015
Experimental orofacial pain and sensory deprivation lead to perceptual distortion of the face in healthy volunteers.
    Experimental brain research, 2015, Volume: 233, Issue:9

    Topics: Adult; Anesthetics, Local; Face; Facial Pain; Female; Healthy Volunteers; Humans; Male; Masseter Mus

2015
Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity?
    Journal of the American Dental Association (1939), 2011, Volume: 142, Issue:5

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anesthetics, Local; Cartica

2011
Toothache of nonodontogenic origin: a case report.
    Journal of endodontics, 2003, Volume: 29, Issue:9

    Topics: Adult; Anesthetics, Local; Facial Pain; Female; Follow-Up Studies; Humans; Injections, Intramuscular

2003
Reduction of clinical temporomandibular joint pain is associated with a reduction of the jaw-stretch reflex.
    Journal of orofacial pain, 2004,Winter, Volume: 18, Issue:1

    Topics: Adult; Analysis of Variance; Anesthetics, Local; Arthralgia; Case-Control Studies; Electromyography;

2004
[Pain induced changes in circulatory dynamics].
    Dental Cadmos, 1991, Sep-15, Volume: 59, Issue:13

    Topics: Blood Pressure; Facial Pain; Female; Heart Rate; Humans; Male; Mepivacaine; Oxygen Consumption; Toot

1991