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mepivacaine and Encephalopathy, Toxic

mepivacaine has been researched along with Encephalopathy, Toxic in 4 studies

Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.

Research Excerpts

ExcerptRelevanceReference
" Although lidocaine is more toxic than bupivacaine and ropivacaine, mepivacaine, which has a similar pharmacological effect to lidocaine, has the least-adverse effects on cone growth among clinically used local anesthetics."1.32Procaine and mepivacaine have less toxicity in vitro than other clinically used local anesthetics. ( Kasaba, T; Onizuka, S; Takasaki, M, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vadi, MG1
Patel, N1
Stiegler, MP1
Calenda, E1
Dinescu, SA1
Kasaba, T1
Onizuka, S1
Takasaki, M1
Salazar, F1
Bogdanovich, A1
Adalia, R1
Chabás, E1
Gomar, C1

Trials

1 trial available for mepivacaine and Encephalopathy, Toxic

ArticleYear
Transient neurologic symptoms after spinal anaesthesia using isobaric 2% mepivacaine and isobaric 2% lidocaine.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure;

2001

Other Studies

3 other studies available for mepivacaine and Encephalopathy, Toxic

ArticleYear
Local anesthetic systemic toxicity after combined psoas compartment-sciatic nerve block: analysis of decision factors and diagnostic delay.
    Anesthesiology, 2014, Volume: 120, Issue:4

    Topics: Aged, 80 and over; Anesthetics, Local; Bradycardia; Bupivacaine; Delayed Diagnosis; Epilepsy, Tonic-

2014
Failure of lipid emulsion to reverse neurotoxicity after an ultrasound-guided axillary block with ropivacaine and mepivacaine.
    Journal of anesthesia, 2009, Volume: 23, Issue:3

    Topics: Aged; Amides; Anesthetics, Local; Axilla; Brain; Electrocardiography; Fat Emulsions, Intravenous; Fo

2009
Procaine and mepivacaine have less toxicity in vitro than other clinically used local anesthetics.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Anesthetics, Local; Animals; Growth Cones; Lymnaea; Mepivacaine; Neurites; Neurons; Neurotoxicity Sy

2003