mepivacaine has been researched along with Diplopia in 7 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Diplopia: A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 38-year-old white woman developed left medical rectus myositis possibly due to an immune response to mepivacaine (Carbocaine) injected around her upper left first molar." | 3.66 | Vertical pendular nystagmus in chronic myositis of medial and lateral rectus. ( Goldberg, RT, 1978) |
| "The study included data sets of annual sales of local anesthetics (from 1995 through 2007), 292 reports to the Danish Medicines Agency, Copenhagen, Denmark, of adverse reactions to local anesthetic drugs, and a clinical sample of 115 patients with NSD associated with local anesthetics." | 1.37 | Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity? ( Ersbøll, BK; Hillerup, S; Jensen, RH, 2011) |
| "Postoperative diplopia and ptosis can be temporary or permanent complications in patients who have undergone ophthalmic surgery while under local anesthesia." | 1.27 | Postoperative diplopia and ptosis. A clinical hypothesis based on the myotoxicity of local anesthetics. ( Carlson, BM; Rainin, EA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Porcel, JM | 1 |
| Brieva, L | 1 |
| Antoni Schoenenberger, J | 1 |
| Hillerup, S | 1 |
| Jensen, RH | 1 |
| Ersbøll, BK | 1 |
| Kronman, JH | 1 |
| Kabani, S | 1 |
| Petrelli, EA | 1 |
| Steller, RE | 1 |
| Goldberg, RT | 1 |
| Rainin, EA | 2 |
| Carlson, BM | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?[NCT03443726] | 120 participants (Actual) | Interventional | 2017-06-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for mepivacaine and Diplopia
| Article | Year |
|---|---|
[Acute transient ataxia caused by local lidocaine injection during insertion of a pleural catheter].
Topics: Acute Disease; Anesthetics, Local; Catheterization; Cerebellar Ataxia; Community-Acquired Infections | 2009 |
Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity?
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anesthetics, Local; Cartica | 2011 |
The neuronal basis for diplopia following local anesthetic injections.
Topics: Adult; Anesthesia, Dental; Carotid Arteries; Diplopia; Face; Female; Humans; Mepivacaine; Sympatheti | 1984 |
Medial rectus muscle palsy after dental anesthesia.
Topics: Adult; Anesthesia, Dental; Diplopia; Female; Humans; Male; Mepivacaine; Middle Aged; Oculomotor Nerv | 1980 |
Vertical pendular nystagmus in chronic myositis of medial and lateral rectus.
Topics: Adult; Chronic Disease; Diplopia; Drug Hypersensitivity; Female; Humans; Lidocaine; Mepivacaine; Myo | 1978 |
Postoperative diplopia and ptosis. A clinical hypothesis based on the myotoxicity of local anesthetics.
Topics: Aged; Anesthetics, Local; Blepharoptosis; Bupivacaine; Cataract Extraction; Diplopia; Epinephrine; F | 1985 |
Rat extraocular muscle regeneration. Repair of local anesthetic-induced damage.
Topics: Anesthetics, Local; Animals; Bupivacaine; Diplopia; Epinephrine; Injections; Lidocaine; Male; Mepiva | 1985 |