Page last updated: 2024-10-30

mepivacaine and Diplopia

mepivacaine has been researched along with Diplopia in 7 studies

Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.

Diplopia: A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.

Research Excerpts

ExcerptRelevanceReference
"A 38-year-old white woman developed left medical rectus myositis possibly due to an immune response to mepivacaine (Carbocaine) injected around her upper left first molar."3.66Vertical pendular nystagmus in chronic myositis of medial and lateral rectus. ( Goldberg, RT, 1978)
"The study included data sets of annual sales of local anesthetics (from 1995 through 2007), 292 reports to the Danish Medicines Agency, Copenhagen, Denmark, of adverse reactions to local anesthetic drugs, and a clinical sample of 115 patients with NSD associated with local anesthetics."1.37Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity? ( Ersbøll, BK; Hillerup, S; Jensen, RH, 2011)
"Postoperative diplopia and ptosis can be temporary or permanent complications in patients who have undergone ophthalmic surgery while under local anesthesia."1.27Postoperative diplopia and ptosis. A clinical hypothesis based on the myotoxicity of local anesthetics. ( Carlson, BM; Rainin, EA, 1985)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Porcel, JM1
Brieva, L1
Antoni Schoenenberger, J1
Hillerup, S1
Jensen, RH1
Ersbøll, BK1
Kronman, JH1
Kabani, S1
Petrelli, EA1
Steller, RE1
Goldberg, RT1
Rainin, EA2
Carlson, BM2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?[NCT03443726]120 participants (Actual)Interventional2017-06-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for mepivacaine and Diplopia

ArticleYear
[Acute transient ataxia caused by local lidocaine injection during insertion of a pleural catheter].
    Archivos de bronconeumologia, 2009, Volume: 45, Issue:9

    Topics: Acute Disease; Anesthetics, Local; Catheterization; Cerebellar Ataxia; Community-Acquired Infections

2009
Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity?
    Journal of the American Dental Association (1939), 2011, Volume: 142, Issue:5

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anesthetics, Local; Cartica

2011
The neuronal basis for diplopia following local anesthetic injections.
    Oral surgery, oral medicine, and oral pathology, 1984, Volume: 58, Issue:5

    Topics: Adult; Anesthesia, Dental; Carotid Arteries; Diplopia; Face; Female; Humans; Mepivacaine; Sympatheti

1984
Medial rectus muscle palsy after dental anesthesia.
    American journal of ophthalmology, 1980, Volume: 90, Issue:3

    Topics: Adult; Anesthesia, Dental; Diplopia; Female; Humans; Male; Mepivacaine; Middle Aged; Oculomotor Nerv

1980
Vertical pendular nystagmus in chronic myositis of medial and lateral rectus.
    Annals of ophthalmology, 1978, Volume: 10, Issue:12

    Topics: Adult; Chronic Disease; Diplopia; Drug Hypersensitivity; Female; Humans; Lidocaine; Mepivacaine; Myo

1978
Postoperative diplopia and ptosis. A clinical hypothesis based on the myotoxicity of local anesthetics.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:9

    Topics: Aged; Anesthetics, Local; Blepharoptosis; Bupivacaine; Cataract Extraction; Diplopia; Epinephrine; F

1985
Rat extraocular muscle regeneration. Repair of local anesthetic-induced damage.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:9

    Topics: Anesthetics, Local; Animals; Bupivacaine; Diplopia; Epinephrine; Injections; Lidocaine; Male; Mepiva

1985