mepivacaine has been researched along with Complication, Intraoperative in 15 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery." | 9.11 | Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005) |
| "To determine the efficacy of a supplemental intraosseous injection of 3% mepivacaine in mandibular posterior teeth with irreversible pulpitis." | 7.69 | Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis. ( Beck, M; Nist, R; Reader, A; Reisman, D; Weaver, J, 1997) |
| "The ephedrine dose required was higher in non-preloaded patients than in preloaded ones (10." | 6.69 | [Preloading with 500 ml of Hartmann's solution lessens the incidence and severity of hypotension and reduces the need for ephedrine after epidural anesthesia in ambulatory patients]. ( Aymerich, H; Cobian-Llamas, JM; Figueira, A; Pensado, A; Rama-Maceiras, P; Rodríguez-Valladares, M, 1999) |
| "To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery." | 5.11 | Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005) |
| "5% hyperbaric bupivacaine with sequential epidural block induced by 5-10 ml of 2% mepivacaine caused no hypotension during cesarean section." | 3.72 | [Combined spinal and epidural anesthesia for cesarean section: a retrospective study with 0.5% hyperbaric bupivacaine]. ( Iwasaki, T; Kasaba, T; Maruta, T; Miura, H; Takasaki, M; Tamura, R, 2004) |
| "An increase in blood pressure, accompanied by atrial fibrillation, agitation, incomprehensible shouts and loss of consciousness, was observed in an elderly, ASA classification group II, cardiovascularly medicated male, 12 min after performance of axillary block with mepivacaine 850 mg containing adrenaline 0." | 3.70 | An unusual toxic reaction to axillary block by mepivacaine with adrenaline. ( Koscielniak-Nielsen, ZJ, 1998) |
| " The development of subdural block was suspected from unexpectedly severe hypotension with small doses of mepivacaine during operation and was confirmed by a characteristic X-ray photograph after operation." | 3.69 | [Diagnosis of accidental subdural block]. ( Fukuda, H; Hirabayashi, Y; Kasuda, H; Mitsuhata, H; Saitoh, K; Shimizu, R, 1995) |
| "To determine the efficacy of a supplemental intraosseous injection of 3% mepivacaine in mandibular posterior teeth with irreversible pulpitis." | 3.69 | Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis. ( Beck, M; Nist, R; Reader, A; Reisman, D; Weaver, J, 1997) |
| "The ephedrine dose required was higher in non-preloaded patients than in preloaded ones (10." | 2.69 | [Preloading with 500 ml of Hartmann's solution lessens the incidence and severity of hypotension and reduces the need for ephedrine after epidural anesthesia in ambulatory patients]. ( Aymerich, H; Cobian-Llamas, JM; Figueira, A; Pensado, A; Rama-Maceiras, P; Rodríguez-Valladares, M, 1999) |
| "Median pain was 0 on the VAS (range 0-5)." | 1.38 | Vasectomy reversal with ultrasonography-guided spermatic cord block. ( Birkhäuser, FD; Eichenberger, U; Greif, R; Luyet, C; Thalmann, GN; Wipfli, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morros, C | 1 |
| Pérez-Cuenca, MD | 1 |
| Sala-Blanch, X | 1 |
| Cedó, F | 1 |
| Birkhäuser, FD | 1 |
| Wipfli, M | 1 |
| Eichenberger, U | 1 |
| Luyet, C | 1 |
| Greif, R | 1 |
| Thalmann, GN | 1 |
| Kasaba, T | 1 |
| Tamura, R | 1 |
| Iwasaki, T | 1 |
| Maruta, T | 1 |
| Miura, H | 1 |
| Takasaki, M | 1 |
| Rebolleda, G | 1 |
| Muñoz-Negrete, FJ | 1 |
| Benatar, J | 1 |
| Corcostegui, J | 1 |
| Alonso, N | 1 |
| Feierman, DE | 1 |
| Mahboobi, SK | 1 |
| Weinberg, G | 1 |
| VadeBoncouer, T | 1 |
| Klöss, T | 1 |
| van Deyk, K | 1 |
| Hempel, V | 1 |
| Saitoh, K | 1 |
| Kasuda, H | 1 |
| Hirabayashi, Y | 1 |
| Fukuda, H | 1 |
| Mitsuhata, H | 1 |
| Shimizu, R | 1 |
| Reisman, D | 1 |
| Reader, A | 1 |
| Nist, R | 1 |
| Beck, M | 1 |
| Weaver, J | 1 |
| Koscielniak-Nielsen, ZJ | 2 |
| Rama-Maceiras, P | 1 |
| Aymerich, H | 1 |
| Pensado, A | 1 |
| Figueira, A | 1 |
| Rodríguez-Valladares, M | 1 |
| Cobian-Llamas, JM | 1 |
| Akata, T | 1 |
| Murakami, J | 1 |
| Yoshinaga, A | 1 |
| Plaja, I | 1 |
| Arxer, A | 1 |
| Metje, M | 1 |
| Santiveri, X | 1 |
| Villalonga, A | 1 |
| Fernández, MA | 1 |
| López, MA | 1 |
| Amaranath, L | 1 |
| Esfandiari, S | 1 |
| Lockrem, J | 1 |
| Rollins, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Evaluation of Preoperative Methylprednisolone or Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis[NCT04157036] | Phase 3 | 3 participants (Actual) | Interventional | 2020-02-01 | Terminated (stopped due to COVID halted recruitment for 2 years. A majority of patients eligible for the study had already taken preoperative analgesics, which disqualified them for the study.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for mepivacaine and Complication, Intraoperative
| Article | Year |
|---|---|
[Contribution of ultrasound guidance to the performance of the axillary brachial plexus block with multiple nerve stimulation].
Topics: Adult; Anesthetics, Local; Axilla; Blood Vessels; Brachial Plexus; Electric Stimulation; Female; Hum | 2009 |
Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage.
Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Female; Gels; Glauc | 2005 |
[Preloading with 500 ml of Hartmann's solution lessens the incidence and severity of hypotension and reduces the need for ephedrine after epidural anesthesia in ambulatory patients].
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Epidural; Anesthetics, Local; Baroreflex; Ephedri | 1999 |
[Comparative study between 5% prilocaine and 2% mepivacaine by the subarachnoid route in transurethral resections].
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Autonomic Nerve Block; Bradycardia; | 2000 |
11 other studies available for mepivacaine and Complication, Intraoperative
| Article | Year |
|---|---|
Vasectomy reversal with ultrasonography-guided spermatic cord block.
Topics: Adult; Aged; Amides; Anesthetics, Local; Feasibility Studies; Humans; Intraoperative Complications; | 2012 |
[Combined spinal and epidural anesthesia for cesarean section: a retrospective study with 0.5% hyperbaric bupivacaine].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupiva | 2004 |
Mepivacaine overdosage is more likely a cause of intraoperative cardiac arrest than drug-drug interaction.
Topics: Drug Interactions; Drug Overdose; Heart Arrest; Humans; Intraoperative Complications; Mepivacaine | 2007 |
Drug interaction or drug overdose? Supercaine revisited.
Topics: Drug Interactions; Drug Overdose; Heart Arrest; Humans; Intraoperative Complications; Mepivacaine; T | 2007 |
[Delayed respiratory arrest following spinal anesthesia].
Topics: Aged; Anesthesia, Spinal; Female; Humans; Intraoperative Complications; Mepivacaine; Respiration Dis | 1984 |
[Diagnosis of accidental subdural block].
Topics: Anesthesia, Epidural; Central Nervous System Diseases; Diagnosis, Differential; Humans; Hypotension; | 1995 |
Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid; Dental Pulp; | 1997 |
An unusual toxic reaction to axillary block by mepivacaine with adrenaline.
Topics: Absorption; Aged; Akathisia, Drug-Induced; Anesthetics, Local; Anti-Arrhythmia Agents; Antihypertens | 1998 |
Life-threatening haemorrhage following obturator artery injury during transurethral bladder surgery: a sequel of an unsuccessful obturator nerve block.
Topics: Aged; Anesthetics, Local; Arteries; Blood Loss, Surgical; Electric Stimulation; Electrosurgery; Huma | 1999 |
Hemidiaphragmatic paresis after interscalene supplementation of insufficient axillary block with 3 mL of 2% mepivacaine.
Topics: Anesthetics, Local; Carcinoma, Non-Small-Cell Lung; Epinephrine; Humans; Intraoperative Complication | 2000 |
Epidural analgesia for total hip replacement in a patient with dilated cardiomyopathy.
Topics: Aged; Analgesia; Anesthesia, Epidural; Blood Pressure; Epinephrine; Heart Diseases; Heart Rate; Hip | 1986 |