Page last updated: 2024-10-30

mepivacaine and Cardiovascular Diseases

mepivacaine has been researched along with Cardiovascular Diseases in 8 studies

Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Torres-Lagares, D1
Serrera-Figallo, MÁ1
Machuca-Portillo, G1
Corcuera-Flores, JR1
Machuca-Portillo, C1
Castillo-Oyagüe, R1
Gutiérrez-Pérez, JL1
Butterworth, JF1
Brownlow, RC1
Leith, JP1
Prielipp, RC1
Cole, LR1
Baur, B1
Sidiropoulos, D1
Schwenzer, N1
Kmoth, M1
Covino, BG1
Nolte, H1
Meyer, J1
Moore, DC1
Bridenbaugh, LD1
Bridenbaugh, PO1
Tucker, GT1
Dam, WH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
2%-Mepivacaine With Two Different Vasoconstrictors; 1:20.000 Levonordefrin or 1:100.000 Epinephrin for Local Anesthesia in Third Molar Surgery: A Comparative Randomized Clinical Trial[NCT02603198]30 participants (Anticipated)Interventional2014-08-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for mepivacaine and Cardiovascular Diseases

ArticleYear
Recent advances in local anaesthesia.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2

    Topics: Acidosis; Anesthesia, Local; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Bupivacaine; Cardiov

1986

Trials

2 trials available for mepivacaine and Cardiovascular Diseases

ArticleYear
Cardiovascular effect of dental anesthesia with articaine (40 mg with epinefrine 0,5 mg % and 40 mg with epinefrine 1 mg%) versus mepivacaine (30 mg and 20 mg with epinefrine 1 mg%) in medically compromised cardiac patients: a cross-over, randomized, sing
    Medicina oral, patologia oral y cirugia bucal, 2012, Jul-01, Volume: 17, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Blood Pressure; Cardiovascular Diseas

2012
[Clinical comparison of Xylonest-Octapressin and Scandicain].
    ZWR, 1991, Volume: 100, Issue:11

    Topics: Anesthesia, Dental; Anesthesia, Local; Cardiovascular Diseases; Dental Care for Disabled; Drug Combi

1991

Other Studies

5 other studies available for mepivacaine and Cardiovascular Diseases

ArticleYear
Bupivacaine inhibits cyclic-3',5'-adenosine monophosphate production. A possible contributing factor to cardiovascular toxicity.
    Anesthesiology, 1993, Volume: 79, Issue:1

    Topics: Adenylyl Cyclases; Adult; Amides; Bupivacaine; Cardiovascular Diseases; Colforsin; Cyclic AMP; Drug

1993
[Complications of local anesthetics in obstetrics as well as in the perinatal period].
    Gynakologische Rundschau, 1976, Volume: 16, Issue:2

    Topics: Anesthesia, Local; Anesthesia, Obstetrical; Anesthetics, Local; Cardiovascular Diseases; Central Ner

1976
[The possibilities of indications for regional anaesthesia].
    Der Anaesthesist, 1972, Volume: 21, Issue:3

    Topics: Ambulatory Care; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, Local; Angiography; B

1972
Caudal and epidural blocks with bupivacaine for childbirth. Report of 657 parturients.
    Obstetrics and gynecology, 1971, Volume: 37, Issue:5

    Topics: Analgesia; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal

1971
Therapeutic blockades.
    Acta chirurgica Scandinavica. Supplementum, 1965, Volume: 343

    Topics: Anesthesia, Conduction; Autonomic Nerve Block; Cardiovascular Diseases; Ethanol; Female; Genital Dis

1965