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mepivacaine and Cardiomegaly

mepivacaine has been researched along with Cardiomegaly in 1 studies

Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"In conclusion, in a model of cardiac hypertrophy such as that of aortic-banding, increased response to alpha1-adrenergic stimulation is observed, which is blunted by mepivacaine administration."1.32Mepivacaine alters vascular responsiveness to vasoconstrictors in aortic rings from normal and aortic-banded rats. ( Cokkinos, D; Karageorgiou, C; Kostopanagiotou, G; Mourouzis, C; Mourouzis, I; Pantos, C; Saranteas, T; Tesseromatis, C; Varonos, D, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mourouzis, C1
Pantos, C1
Mourouzis, I1
Saranteas, T1
Tesseromatis, C1
Kostopanagiotou, G1
Karageorgiou, C1
Varonos, D1
Cokkinos, D1

Other Studies

1 other study available for mepivacaine and Cardiomegaly

ArticleYear
Mepivacaine alters vascular responsiveness to vasoconstrictors in aortic rings from normal and aortic-banded rats.
    Pharmacology & toxicology, 2003, Volume: 93, Issue:6

    Topics: Anesthetics, Local; Animals; Aorta; Cardiomegaly; Constriction; Endothelium, Vascular; Male; Mepivac

2003