mepivacaine has been researched along with Cardiac Hypertrophy in 1 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In conclusion, in a model of cardiac hypertrophy such as that of aortic-banding, increased response to alpha1-adrenergic stimulation is observed, which is blunted by mepivacaine administration." | 1.32 | Mepivacaine alters vascular responsiveness to vasoconstrictors in aortic rings from normal and aortic-banded rats. ( Cokkinos, D; Karageorgiou, C; Kostopanagiotou, G; Mourouzis, C; Mourouzis, I; Pantos, C; Saranteas, T; Tesseromatis, C; Varonos, D, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mourouzis, C | 1 |
| Pantos, C | 1 |
| Mourouzis, I | 1 |
| Saranteas, T | 1 |
| Tesseromatis, C | 1 |
| Kostopanagiotou, G | 1 |
| Karageorgiou, C | 1 |
| Varonos, D | 1 |
| Cokkinos, D | 1 |
1 other study available for mepivacaine and Cardiac Hypertrophy
| Article | Year |
|---|---|
Mepivacaine alters vascular responsiveness to vasoconstrictors in aortic rings from normal and aortic-banded rats.
Topics: Anesthetics, Local; Animals; Aorta; Cardiomegaly; Constriction; Endothelium, Vascular; Male; Mepivac | 2003 |