mepivacaine has been researched along with Bradycardia in 31 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Presumably the condition occurred because of a toxic effect of the 400 mg of mepivacaine administered paracervically." | 5.31 | Severe bradycardia and bradypnea following vaginal oocyte retrieval: a possible toxic effect of paracervical mepivacaine. ( Arce, D; Ayestaran, C; Gomez, S; Matorras, R; Rodriguez-Escudero, F, 2000) |
| " Presumably the condition occurred because of a toxic effect of the 400 mg of mepivacaine administered paracervically." | 1.31 | Severe bradycardia and bradypnea following vaginal oocyte retrieval: a possible toxic effect of paracervical mepivacaine. ( Arce, D; Ayestaran, C; Gomez, S; Matorras, R; Rodriguez-Escudero, F, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (80.65) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vadi, MG | 1 |
| Patel, N | 1 |
| Stiegler, MP | 1 |
| Gordon, HR | 1 |
| Shnider, M | 1 |
| Asling, JH | 2 |
| Margolis, AJ | 2 |
| Way, EL | 2 |
| Wilkinson, GR | 1 |
| LeFevre, ML | 1 |
| Braun, U | 1 |
| Feise, J | 1 |
| Mühlendyck, H | 1 |
| Bruelle, P | 1 |
| LeFrant, JY | 1 |
| de La Coussaye, JE | 1 |
| Peray, PA | 1 |
| Desch, G | 1 |
| Sassine, A | 1 |
| Eledjam, JJ | 1 |
| Singelyn, FJ | 1 |
| Gouverneur, JM | 1 |
| Robert, A | 1 |
| Ayestaran, C | 1 |
| Matorras, R | 1 |
| Gomez, S | 1 |
| Arce, D | 1 |
| Rodriguez-Escudero, F | 1 |
| Plaja, I | 1 |
| Arxer, A | 1 |
| Metje, M | 1 |
| Santiveri, X | 1 |
| Villalonga, A | 1 |
| Fernández, MA | 1 |
| López, MA | 1 |
| Sehhati, G | 1 |
| Frey, R | 1 |
| Mildner, R | 1 |
| Stockhausen, H | 1 |
| Diesbecq, W | 1 |
| Rolly, G | 1 |
| Thiery, M | 1 |
| LeHew, WL | 1 |
| Paul, RH | 2 |
| Freeman, RK | 2 |
| Gutierrez, NA | 1 |
| Ray, ML | 1 |
| Stovall, D | 1 |
| Hon, EH | 1 |
| Hamilton, LA | 1 |
| Gottschalk, W | 1 |
| Hickl, EJ | 1 |
| Gennser, G | 1 |
| Vasicka, A | 1 |
| Robertazzi, R | 1 |
| Raji, M | 1 |
| Scheffs, J | 1 |
| Kosmowski, J | 1 |
| Goei, T | 1 |
| Martin, K | 1 |
| Rathgen, GH | 1 |
| Schwethelm, R | 1 |
| Beck, L | 1 |
| Teramo, K | 3 |
| Rogers, RE | 1 |
| Shnider, SM | 1 |
| Wilkinson, GL | 1 |
| Hermann, K | 1 |
| Stadler, GC | 1 |
| Goddard, WB | 1 |
| Bernier, G | 1 |
| Turcot, MJ | 1 |
| Rajamäki, A | 1 |
| Rosefsky, JB | 1 |
| Petersiel, ME | 1 |
| Ekblom, L | 1 |
| Widman, B | 1 |
2 trials available for mepivacaine and Bradycardia
| Article | Year |
|---|---|
A minimum dose of clonidine added to mepivacaine prolongs the duration of anesthesia and analgesia after axillary brachial plexus block.
Topics: Adrenergic alpha-Agonists; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics; Anesthetics | 1996 |
[Comparative study between 5% prilocaine and 2% mepivacaine by the subarachnoid route in transurethral resections].
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Autonomic Nerve Block; Bradycardia; | 2000 |
29 other studies available for mepivacaine and Bradycardia
| Article | Year |
|---|---|
Local anesthetic systemic toxicity after combined psoas compartment-sciatic nerve block: analysis of decision factors and diagnostic delay.
Topics: Aged, 80 and over; Anesthetics, Local; Bradycardia; Bupivacaine; Delayed Diagnosis; Epilepsy, Tonic- | 2014 |
Fetal bradycardia after paracervical block. Correlation with fetal and maternal blood levels of local anesthetic (mepivacaine).
Topics: Anesthesia, Obstetrical; Anesthetics, Local; Bradycardia; Female; Fetal Diseases; Heart Rate, Fetal; | 1968 |
High fetal blood levels of mepivacaine and fetal bradycardia.
Topics: Anesthesia, Obstetrical; Anesthetics, Local; Bradycardia; Chromatography, Liquid; Female; Fetal Deat | 1968 |
Fetal heart rate pattern and postparacervical fetal bradycardia.
Topics: Anesthesia, Obstetrical; Autonomic Nerve Block; Bradycardia; Female; Fetal Diseases; Fetal Heart; Fe | 1984 |
Is there a cholinergic and an adrenergic phase of the oculocardiac reflex during strabismus surgery?
Topics: Adolescent; Atropine; Bradycardia; Child; Child, Preschool; Electrocardiography; Female; Heart Rate; | 1993 |
Comparative electrophysiologic and hemodynamic effects of several amide local anesthetic drugs in anesthetized dogs.
Topics: Amides; Anesthetics, Local; Animals; Aorta; Atrial Function; Atrioventricular Node; Blood Pressure; | 1996 |
Severe bradycardia and bradypnea following vaginal oocyte retrieval: a possible toxic effect of paracervical mepivacaine.
Topics: Adult; Analgesia, Obstetrical; Anesthetics, Local; Bradycardia; Dyspnea; Female; Fertilization in Vi | 2000 |
[Perinatal deaths associated with paracervical anesthesia (author's transl)].
Topics: Adult; Anesthesia, Obstetrical; Anesthetics; Anesthetics, Local; Apgar Score; Bradycardia; Bupivacai | 1975 |
[Complications of regional anaesthesia and their treatment (author's transl)].
Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis | 1973 |
Paracervical block in obstetrics.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Female; Fetus; Humans; Mepivacaine; Ob | 1968 |
[Paracervical block and its effect on fetus].
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Bupivacaine; Cervix Uteri; Female; Fet | 1970 |
Continuous lumbar epidural analgesia during labor and delivery.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Back Pain; Bradycardia; Bupivacaine; Female; F | 1974 |
Paracervical block in obstetrics.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Female; Fetal Diseases; Fetal Heart; H | 1972 |
Fetal cardiac response to paracervical block anesthesia. II.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Obstetrical; Apgar Score; Bradycardia; Cesarean Section; | 1972 |
Fetal cardiac response to paracervical block anesthesia. I.
Topics: Acidosis; Anesthesia, Conduction; Anesthesia, Obstetrical; Apgar Score; Bradycardia; Electrocardiogr | 1972 |
Paracervical block: advantages and disadvantages.
Topics: Acidosis; Anesthesia, Obstetrical; Anesthetics, Local; Bradycardia; Cervix Uteri; Female; Fetal Dise | 1974 |
[The effect of paracervical block on the fetus].
Topics: Acidosis; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, Local; Asphyxia Neonatorum; | 1972 |
Fetal bradycardia after paracervical block.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Catheterization; Cervix Uteri; Epineph | 1971 |
[Blood level of mepivacaine (scandicaine) following paracervical block].
Topics: Anesthesia, Obstetrical; Autonomic Nerve Block; Bicarbonates; Blood; Bradycardia; Carbon Dioxide; Fe | 1969 |
[Effects of local anaesthetics on the foetus].
Topics: Acidosis; Analgesia; Anesthetics, Local; Anilides; Asphyxia; Blood Pressure; Bradycardia; Female; Fe | 1969 |
Studies on foetal acid-base values after paracervical blockade during labour.
Topics: Acid-Base Equilibrium; Acidosis; Anesthesia, Obstetrical; Anesthetics, Local; Blood Vessels; Bradyca | 1969 |
Fetal bradycardia associated with paracervical block anesthesia in labor.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Female; Fetal Heart; Humans; Infant, N | 1970 |
Paracervical block anesthesia in obstetrics. II. Etiology of fetal bradycardia following paracervical block anesthesia.
Topics: Acidosis; Adult; Anesthesia, Obstetrical; Autonomic Nerve Block; Bradycardia; Female; Fetal Diseases | 1970 |
[Routine use of pudendal and paracervical anesthesias].
Topics: Adult; Anesthesia, Conduction; Anesthesia, Obstetrical; Apgar Score; Bradycardia; Cervix Uteri; Extr | 1970 |
Fetal monitoring in a private hospital. Observations of fetal bradycardia following paracervical block anesthesia.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Cervix Uteri; Female; Fetal Heart; Hea | 1971 |
[Paracervical block in obstetrics].
Topics: Anesthesia, Local; Anesthesia, Obstetrical; Bradycardia; Cervix Uteri; Female; Fetal Diseases; Human | 1971 |
Foetal and maternal plasma levels of mepivacaine and foetal acid-base balance and heart rate after paracervical block during labour.
Topics: Acid-Base Equilibrium; Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Carbon Dioxide; | 1971 |
Perinatal deaths associated with mepivacaine paracervical-block anesthesia in labor.
Topics: Acidosis; Adolescent; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Bradycardia; Female; Fetal | 1968 |
A comparison of the properties of LAC-43, prilocaine and mepivacaine in extradural anaesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Bradycardia; Epinephrine; Humans; Mepivacaine; Nausea; Tremor | 1966 |