mepivacaine has been researched along with Blindness in 4 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Blindness: The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three patients with advanced refractory glaucoma undergoing laser cyclophotocoagulation (CPC) for intraocular pressure lowering experienced these adverse effects just few minutes after subconjunctival injection of mepivacaine 2% solution (Scandicaine® 2%, without vasoconstrictor supplementation)." | 7.91 | Ipsilateral transient amaurosis, mydriasis and light reflex absence after subconjunctival local anesthesia with mepivacaine in three patients with refractory glaucoma - a case report. ( Chobanyan-Jürgens, K; Framme, C; Hufendiek, K; Knoll, K; Stichtenoth, DO; Volkmann, IR, 2019) |
| "Three patients with advanced refractory glaucoma undergoing laser cyclophotocoagulation (CPC) for intraocular pressure lowering experienced these adverse effects just few minutes after subconjunctival injection of mepivacaine 2% solution (Scandicaine® 2%, without vasoconstrictor supplementation)." | 3.91 | Ipsilateral transient amaurosis, mydriasis and light reflex absence after subconjunctival local anesthesia with mepivacaine in three patients with refractory glaucoma - a case report. ( Chobanyan-Jürgens, K; Framme, C; Hufendiek, K; Knoll, K; Stichtenoth, DO; Volkmann, IR, 2019) |
| "A few minutes later, an amaurosis of the treated eyes was found in both patients, which was fully reversible after 2 to 3 hours." | 1.31 | [Transient blindness after subconjunctival anesthesia for diode laser cyclophotocoagulation]. ( Freudenthaler, N; Rohrbach, JM; Schlote, T; von Eicken, J, 2000) |
| "Contralateral amaurosis after retrobulbar injection of local anesthetic agents occurred in two patients, a 64-year-old woman and a 57-year-old man." | 1.27 | Contralateral amaurosis after retrobulbar injection. ( Friedberg, HL; Kline, OR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knoll, K | 1 |
| Chobanyan-Jürgens, K | 1 |
| Stichtenoth, DO | 1 |
| Volkmann, IR | 1 |
| Hufendiek, K | 1 |
| Framme, C | 1 |
| Schlote, T | 1 |
| Freudenthaler, N | 1 |
| von Eicken, J | 1 |
| Rohrbach, JM | 1 |
| Fischer, H | 1 |
| Häberle, M | 1 |
| Hornstein, OP | 1 |
| Friedberg, HL | 1 |
| Kline, OR | 1 |
4 other studies available for mepivacaine and Blindness
| Article | Year |
|---|---|
Ipsilateral transient amaurosis, mydriasis and light reflex absence after subconjunctival local anesthesia with mepivacaine in three patients with refractory glaucoma - a case report.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Blindness; Ciliary Body; Conjunctiva; Glaucoma, Open-An | 2019 |
[Transient blindness after subconjunctival anesthesia for diode laser cyclophotocoagulation].
Topics: Aged; Anesthesia, Local; Blindness; Ciliary Body; Conjunctiva; Exfoliation Syndrome; Glaucoma, Open- | 2000 |
[Transient vision loss caused by scandicaine with added arterenol in the excision of basalioma of the side of the nose].
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Blindness; Carcinoma, Basal Cell; Female; Humans; Mepiv | 1987 |
Contralateral amaurosis after retrobulbar injection.
Topics: Akathisia, Drug-Induced; Anesthesia, Local; Blindness; Bupivacaine; Eye; Female; Humans; Injections; | 1986 |