mepivacaine has been researched along with Arrhythmia in 18 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fatal cardiac arrhythmias occurred in, respectively, 3 of 11, 2 of 12, and 2 of 13 conscious sheep infused with bupivacaine, levobupivacaine, and ropivacaine; in 1 of 9 with prilocaine, electromechanical dissociation (followed by polymorphic ventricular tachycardia) caused death." | 3.74 | The effects of general anesthesia on the central nervous and cardiovascular system toxicity of local anesthetics. ( Copeland, SE; Gu, XQ; Ladd, LA; Mather, LE, 2008) |
| "The patient experienced seizures and dysrhythmias twenty minutes after block completion and injection of the anesthetic solution [Ropivacaine 0." | 1.31 | Acute toxicity of local anesthetic ropivacaine and mepivacaine during a combined lumbar plexus and sciatic block for hip surgery. ( Auffray, JP; Gaillat, F; Lavand'homme, P; Mullanu, Ch; Scemama, F; Thibault, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (66.67) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krzemiński, TF | 1 |
| Mitrega, K | 1 |
| Zorniak, M | 1 |
| Porc, M | 1 |
| Mullanu, Ch | 1 |
| Gaillat, F | 1 |
| Scemama, F | 1 |
| Thibault, S | 1 |
| Lavand'homme, P | 1 |
| Auffray, JP | 1 |
| WIEDLING, S | 1 |
| TEGNER, C | 1 |
| NAVARIVERA, A | 1 |
| VEGAESQUIVEL, E | 1 |
| LOPEZ, AJ | 1 |
| Copeland, SE | 1 |
| Ladd, LA | 1 |
| Gu, XQ | 1 |
| Mather, LE | 1 |
| Hartung, HJ | 1 |
| Osswald, PM | 1 |
| Tolksdorf, W | 1 |
| Bender, HJ | 1 |
| Lutz, H | 1 |
| Kamibayashi, T | 1 |
| Hayashi, Y | 1 |
| Mammoto, T | 1 |
| Yamatodani, A | 1 |
| Taenaka, N | 1 |
| Yoshiya, I | 1 |
| Frabetti, L | 1 |
| Checchi, L | 1 |
| Finelli, K | 1 |
| Hoepp, HW | 1 |
| Eggeling, T | 1 |
| Hombach, V | 1 |
| Covino, BG | 1 |
| Kasten, GW | 1 |
| Clodius, L | 1 |
| Smahel, J | 1 |
| Telivuo, L | 1 |
| Katz, RL | 1 |
| Boettner, RB | 1 |
| Dunbar, RW | 1 |
| Haley, JV | 1 |
| Morrow, DH | 1 |
| Gjessing, J | 1 |
| Usubiaga, JE | 1 |
| La Iuppa, M | 1 |
| Moya, F | 1 |
| Wikinski, JA | 1 |
| Velazco, R | 1 |
| Barile, C | 2 |
| Zuccaro, GM | 2 |
| Musto, P | 2 |
| Graziani, M | 1 |
| Orecchia, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429] | Phase 4 | 144 participants (Anticipated) | Interventional | 2019-04-05 | Recruiting | ||
| Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573] | Phase 1 | 31 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mepivacaine and Arrhythmia
| Article | Year |
|---|---|
LOCAL ANESTHETICS.
Topics: Analgesia; Anesthetics; Anesthetics, Local; Arrhythmias, Cardiac; Benzoates; Cough; Ethers; Ketones; | 1963 |
Recent advances in local anaesthesia.
Topics: Acidosis; Anesthesia, Local; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Bupivacaine; Cardiov | 1986 |
1 trial available for mepivacaine and Arrhythmia
| Article | Year |
|---|---|
The effects of modern intravenous local analgesics on respiration during partial neuromuscular block in man.
Topics: Anesthesia, Intravenous; Anesthetics, Local; Anilides; Arrhythmias, Cardiac; Central Nervous System; | 1970 |
15 other studies available for mepivacaine and Arrhythmia
| Article | Year |
|---|---|
Differential effects of four xylidine derivatives in the model of ischemia- and re-perfusion-induced arrhythmias in rats in vivo.
Topics: Amides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; C | 2010 |
Acute toxicity of local anesthetic ropivacaine and mepivacaine during a combined lumbar plexus and sciatic block for hip surgery.
Topics: Aged; Aged, 80 and over; Amides; Anesthetics, Local; Arrhythmias, Cardiac; Female; Femoral Neck Frac | 2002 |
[COUNTEREFFECT OF LOCAL BLOCKING AGENTS ON CARDIAC ARRHYTHMIA].
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Complexes, Premature; Cardiac Conduction System Dise | 1965 |
The effects of general anesthesia on the central nervous and cardiovascular system toxicity of local anesthetics.
Topics: Acid-Base Equilibrium; Amides; Anesthetics, Inhalation; Anesthetics, Local; Animals; Arrhythmias, Ca | 2008 |
[Incidence of complications with plexus anaesthesia; a computer-assisted evaluation (author's transl)].
Topics: Anesthesia, Conduction; Arrhythmias, Cardiac; Cervical Plexus; Computers; Humans; Hypertension; Hypo | 1982 |
Thoracic epidural anesthesia attenuates halothane-induced myocardial sensitization to dysrhythmogenic effect of epinephrine in dogs.
Topics: Anesthesia, Epidural; Animals; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Drug In | 1995 |
Cardiovascular effects of local anesthesia with epinephrine in periodontal treatment.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Arrhythmias, Cardiac; Blood Pressure; Chil | 1992 |
Pharmacologic blockade of the left stellate ganglion using a drug-reservoir-pump system.
Topics: Adult; Arrhythmias, Cardiac; Female; Ganglionic Blockers; Humans; Infusion Pumps, Implantable; Long | 1990 |
Amide local anesthetic alterations of effective refractory period temporal dispersion: relationship to ventricular arrhythmias.
Topics: Amides; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Bupivacaine; Dogs; Electrocardiography; E | 1986 |
POR 8, a new vasoconstrictor substitute for adrenaline in plastic surgery.
Topics: Adolescent; Aged; Anesthesia, General; Anesthesia, Local; Arrhythmias, Cardiac; Epinephrine; Female; | 1970 |
The comparative antiarrhythmic effects of mepivacaine and lignocaine.
Topics: Anesthesia, Local; Animals; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Electrocardiography; H | 1970 |
[Carbocaine as a drug against arrhythmia].
Topics: Arrhythmias, Cardiac; Electrocardiography; Humans; Injections, Intravenous; Lidocaine; Male; Mepivac | 1971 |
Passage of procaine hydrochloride and para-aminobenzoic acid across the human placenta.
Topics: Adjuvants, Anesthesia; Aminobenzoates; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, | 1968 |
[Antiarrhythmic action of modern local anesthetics. I. Action on experimental arrhythmias induced with ouabain].
Topics: Anesthetics, Local; Anilides; Animals; Arrhythmias, Cardiac; Female; Lidocaine; Male; Mepivacaine; O | 1969 |
[Antiarrhythmic action of modern local anesthetics. II. Action on experimental arrhythmias induced with adrenaline].
Topics: Anesthetics, Local; Anilides; Animals; Arrhythmias, Cardiac; Epinephrine; Female; Lidocaine; Male; M | 1969 |