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mephenytoin and Chronic Hepatitis

mephenytoin has been researched along with Chronic Hepatitis in 1 studies

Mephenytoin: An anticonvulsant effective in tonic-clonic epilepsy (EPILEPSY, TONIC-CLONIC). It may cause blood dyscrasias.
mephenytoin : An imidazolidine-2,4-dione (hydantoin) in which the imidazolidine nucleus carries a methyl group at N-3 and has ethyl and phenyl substituents at C-5. An anticonvulsant, it is no longer available in the USA or the UK but is still studied largely because of its interesting hydroxylation polymorphism.

Research Excerpts

ExcerptRelevanceReference
" An alternative approach is to measure the hepatic metabolism of a highly extracted compound whose oral clearance and systemic bioavailability are dependent on both hepatocyte function and degree of portosystemic shunt."1.30Mephenytoin disposition and serum bile acids as indices of hepatic function in chronic viral hepatitis. ( Adedoyin, A; Arns, PA; Branch, RA; DiBisceglie, AM; Hoofnagle, JH; Waggoner, JG; Wilkinson, GR, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arns, PA1
Adedoyin, A1
DiBisceglie, AM1
Waggoner, JG1
Hoofnagle, JH1
Wilkinson, GR1
Branch, RA1

Other Studies

1 other study available for mephenytoin and Chronic Hepatitis

ArticleYear
Mephenytoin disposition and serum bile acids as indices of hepatic function in chronic viral hepatitis.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:5

    Topics: Adult; Analysis of Variance; Anticonvulsants; Biological Availability; Glycocholic Acid; Hepatitis,

1997