mephenytoin has been researched along with Arrhythmias, Cardiac in 1 studies
Mephenytoin: An anticonvulsant effective in tonic-clonic epilepsy (EPILEPSY, TONIC-CLONIC). It may cause blood dyscrasias.
mephenytoin : An imidazolidine-2,4-dione (hydantoin) in which the imidazolidine nucleus carries a methyl group at N-3 and has ethyl and phenyl substituents at C-5. An anticonvulsant, it is no longer available in the USA or the UK but is still studied largely because of its interesting hydroxylation polymorphism.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone has been shown to interact with the nongenetically determined hepatic elimination of several drugs, including phenytoin and digoxin." | 1.28 | Influence of amiodarone on genetically determined drug metabolism in humans. ( Funck-Brentano, C; Jacqz-Aigrain, E; Jaillon, P; Leenhardt, A; Poirier, JM; Roux, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Funck-Brentano, C | 1 |
| Jacqz-Aigrain, E | 1 |
| Leenhardt, A | 1 |
| Roux, A | 1 |
| Poirier, JM | 1 |
| Jaillon, P | 1 |
1 other study available for mephenytoin and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Influence of amiodarone on genetically determined drug metabolism in humans.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Arylamine N-Acetyltransferase; Cyt | 1991 |