mephentermine has been researched along with Pregnancy in 17 studies
Mephentermine: A sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maintain BLOOD PRESSURE in hypotensive states such as following SPINAL ANESTHESIA.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compared the effects of intravenous infusions of phenylephrine and mephentermine on the prevention of maternal hypotension and neonatal outcome in patients receiving spinal anaesthesia for caesarean section." | 9.14 | Comparison of phenylephrine hydrochloride and mephentermine sulphate for prevention of post spinal hypotension. ( Agarwal, D; Janani, SS; Mohta, M; Sethi, AK; Tyagi, A, 2010) |
| "The dosages and potency of intravenous mephentermine for prevention of post-spinal hypotension are not available in English literature." | 9.13 | Comparison of potency of ephedrine and mephentermine for prevention of post-spinal hypotension in caesarean section. ( Agarwal, D; Gupta, A; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2008) |
| "This study was designed to determine the minimum effective dose (ED50) of mephentermine for prevention of post-spinal hypotension in women undergoing elective caesarean section." | 7.75 | Potency of mephentermine for prevention of post-spinal hypotension. ( Agarwal, D; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2009) |
| "Hypotension was defined as a decrease in systolic blood pressure of > or = 20% from the baseline value or an absolute value of <100 mmHg, whichever was higher." | 6.71 | Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anaesthesia for Caesarean section. ( Kansal, A; Kumar, P; Mohta, M; Sethi, AK; Tyagi, A, 2005) |
| "Therefore mephentermin is suitable for treatment of hypotension in pregnancy." | 5.26 | [Suitability of mephentermine for the management of arterial hypotension in pregnancy]. ( Lauckner, W; Retzke, U; Schwarz, R, 1978) |
| "This study compared the effects of intravenous infusions of phenylephrine and mephentermine on the prevention of maternal hypotension and neonatal outcome in patients receiving spinal anaesthesia for caesarean section." | 5.14 | Comparison of phenylephrine hydrochloride and mephentermine sulphate for prevention of post spinal hypotension. ( Agarwal, D; Janani, SS; Mohta, M; Sethi, AK; Tyagi, A, 2010) |
| "The dosages and potency of intravenous mephentermine for prevention of post-spinal hypotension are not available in English literature." | 5.13 | Comparison of potency of ephedrine and mephentermine for prevention of post-spinal hypotension in caesarean section. ( Agarwal, D; Gupta, A; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2008) |
| "This study was designed to determine the minimum effective dose (ED50) of mephentermine for prevention of post-spinal hypotension in women undergoing elective caesarean section." | 3.75 | Potency of mephentermine for prevention of post-spinal hypotension. ( Agarwal, D; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2009) |
| "Hypotension was defined as a decrease in systolic blood pressure of > or = 20% from the baseline value or an absolute value of <100 mmHg, whichever was higher." | 2.71 | Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anaesthesia for Caesarean section. ( Kansal, A; Kumar, P; Mohta, M; Sethi, AK; Tyagi, A, 2005) |
| "Therefore mephentermin is suitable for treatment of hypotension in pregnancy." | 1.26 | [Suitability of mephentermine for the management of arterial hypotension in pregnancy]. ( Lauckner, W; Retzke, U; Schwarz, R, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Agarwal, S | 1 |
| Kumar, M | 1 |
| Gupta, A | 2 |
| Rautela, RS | 1 |
| Jain, N | 1 |
| Mohta, M | 4 |
| Agarwal, D | 3 |
| Gupta, LK | 2 |
| Tyagi, A | 4 |
| Sethi, AK | 4 |
| Makkar, JK | 1 |
| Wig, J | 1 |
| Janani, SS | 1 |
| Kansal, A | 1 |
| Kumar, P | 1 |
| Lauckner, W | 1 |
| Schwarz, R | 1 |
| Retzke, U | 1 |
| Chestnut, DH | 1 |
| Ostman, LG | 1 |
| Weiner, CP | 1 |
| Hdez, MJ | 1 |
| Wang, JP | 1 |
| Levinson, G | 1 |
| Shnider, SM | 2 |
| Van Nimwegen, D | 1 |
| Dyer, DC | 1 |
| Wadhwa, RK | 1 |
| Wadhwa, SR | 1 |
| Khurana, RC | 1 |
| Ralston, DH | 1 |
| DeLorimier, AA | 1 |
| SentÃes, L | 2 |
| Arellano, G | 2 |
| Casellas, A | 1 |
| Ontiveros, E | 1 |
| Santos, J | 1 |
| James, FM | 1 |
| Greiss, FC | 1 |
| Kemp, RA | 1 |
| Gelehrter, TD | 1 |
| Brienza, A | 1 |
| De Leonardis, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital[NCT05706727] | Phase 3 | 42 participants (Anticipated) | Interventional | 2023-03-23 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mephentermine and Pregnancy
| Article | Year |
|---|---|
Vasopressors in obstetrics.
Topics: Angiotensin II; Drug Synergism; Ephedrine; Epinephrine; Female; Humans; Hypotension; Isoproterenol; | 1974 |
4 trials available for mephentermine and Pregnancy
| Article | Year |
|---|---|
Effect of Intravenous Calcium Gluconate on Prevention of Post Spinal Hypotension during Spinal Anaesthesia for Caesarean Section: A Randomized Double-Blind Controlled Study.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Calcium; Calcium Gluconate; Cesarean Section; Double-Bl | 2022 |
Comparison of potency of ephedrine and mephentermine for prevention of post-spinal hypotension in caesarean section.
Topics: Adult; Anesthesia, Spinal; Cesarean Section; Double-Blind Method; Ephedrine; Female; Heart Rate; Hum | 2008 |
Comparison of phenylephrine hydrochloride and mephentermine sulphate for prevention of post spinal hypotension.
Topics: Adrenergic alpha-1 Receptor Agonists; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pres | 2010 |
Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anaesthesia for Caesarean section.
Topics: Adrenergic Agents; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Apgar Score; Cesarean Section | 2005 |
12 other studies available for mephentermine and Pregnancy
| Article | Year |
|---|---|
Potency of mephentermine for prevention of post-spinal hypotension.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotension; M | 2009 |
Up-down study--is the analysis adequate?
Topics: Adult; Anesthesia, Spinal; Cesarean Section; Ephedrine; Female; Humans; Hypotension; Mephentermine; | 2010 |
[Suitability of mephentermine for the management of arterial hypotension in pregnancy].
Topics: Drug Evaluation; Female; Germany, East; Hemodynamics; Humans; Hypotension; Mephentermine; Pregnancy; | 1978 |
The effect of vasopressor agents upon uterine artery blood flow velocity in the gravid guinea pig subjected to ritodrine infusion.
Topics: Animals; Blood Flow Velocity; Ephedrine; Epinephrine; Female; Guinea Pigs; Mephentermine; Obstetric | 1988 |
The action of vasopressors on isolated uterine arteries.
Topics: Adult; Animals; Arteries; Carbon Dioxide; Dopamine; Dose-Response Relationship, Drug; Ephedrine; Epi | 1974 |
Cardiovascular collapse unrelated to anaesthesia. An undiagnosed ectopic pregnancy.
Topics: Adult; Anesthesia, General; Blood Transfusion; Curettage; Dilatation; Female; Humans; Hypotension; K | 1974 |
Effects of equipotent ephedrine, metaraminol, mephentermine, and methoxamine on uterine blood flow in the pregnant ewe.
Topics: Acid-Base Equilibrium; Anesthesia, Local; Anesthesia, Obstetrical; Anesthesia, Spinal; Animals; Bloo | 1974 |
[Hazards in the use of some cardiovascular drugs in pregnant women].
Topics: Amniotic Fluid; Female; Humans; Mephentermine; Methoxamine; Octopamine; Ouabain; Pregnancy; Pregnanc | 1968 |
Effects of some vasopressor drugs upon uterine contractility in pregnant women.
Topics: Amniotic Fluid; Anencephaly; Blood Pressure; Female; Fetal Death; Fetal Heart; Heart Rate; Humans; I | 1970 |
An evaluation of vasopressor therapy for maternal hypotension during spinal anesthesia.
Topics: Anesthesia, Spinal; Animals; Cardiac Output; Ephedrine; Female; Hypotension; Mephentermine; Metarami | 1970 |
Lysergic acid diethylamide (LSD) and exstrophy of the bladder.
Topics: Abnormalities, Drug-Induced; Adult; Bladder Exstrophy; Cannabis; Female; Humans; Infant, Newborn; Ly | 1970 |
[The choice of the pressor drug in hypotension caused by peridural anesthesia. Observations with methoxamine, metaraminol and mephentermine].
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotensi | 1967 |