mephentermine has been researched along with Blood Pressure, Low in 32 studies
Mephentermine: A sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maintain BLOOD PRESSURE in hypotensive states such as following SPINAL ANESTHESIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compared the effects of intravenous infusions of phenylephrine and mephentermine on the prevention of maternal hypotension and neonatal outcome in patients receiving spinal anaesthesia for caesarean section." | 9.14 | Comparison of phenylephrine hydrochloride and mephentermine sulphate for prevention of post spinal hypotension. ( Agarwal, D; Janani, SS; Mohta, M; Sethi, AK; Tyagi, A, 2010) |
| "The dosages and potency of intravenous mephentermine for prevention of post-spinal hypotension are not available in English literature." | 9.13 | Comparison of potency of ephedrine and mephentermine for prevention of post-spinal hypotension in caesarean section. ( Agarwal, D; Gupta, A; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2008) |
| "This study was designed to determine the minimum effective dose (ED50) of mephentermine for prevention of post-spinal hypotension in women undergoing elective caesarean section." | 7.75 | Potency of mephentermine for prevention of post-spinal hypotension. ( Agarwal, D; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2009) |
| "Hypotension was defined as a decrease in systolic blood pressure of > or = 20% from the baseline value or an absolute value of <100 mmHg, whichever was higher." | 6.71 | Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anaesthesia for Caesarean section. ( Kansal, A; Kumar, P; Mohta, M; Sethi, AK; Tyagi, A, 2005) |
| "Therefore mephentermin is suitable for treatment of hypotension in pregnancy." | 5.26 | [Suitability of mephentermine for the management of arterial hypotension in pregnancy]. ( Lauckner, W; Retzke, U; Schwarz, R, 1978) |
| "This study compared the effects of intravenous infusions of phenylephrine and mephentermine on the prevention of maternal hypotension and neonatal outcome in patients receiving spinal anaesthesia for caesarean section." | 5.14 | Comparison of phenylephrine hydrochloride and mephentermine sulphate for prevention of post spinal hypotension. ( Agarwal, D; Janani, SS; Mohta, M; Sethi, AK; Tyagi, A, 2010) |
| "The dosages and potency of intravenous mephentermine for prevention of post-spinal hypotension are not available in English literature." | 5.13 | Comparison of potency of ephedrine and mephentermine for prevention of post-spinal hypotension in caesarean section. ( Agarwal, D; Gupta, A; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2008) |
| " Midazolam with bupivacaine prolongs the duration of analgesia when administered intrathecally but does not prevent hypotension." | 5.13 | Combination of low doses of intrathecal ketamine and midazolam with bupivacaine improves postoperative analgesia in orthopaedic surgery. ( Batra, YK; Murali Krishna, T; Panda, NB; Rajeev, S, 2008) |
| "This study was designed to determine the minimum effective dose (ED50) of mephentermine for prevention of post-spinal hypotension in women undergoing elective caesarean section." | 3.75 | Potency of mephentermine for prevention of post-spinal hypotension. ( Agarwal, D; Gupta, LK; Mohta, M; Sethi, AK; Tyagi, A, 2009) |
| "Hypotension was defined as a decrease in systolic blood pressure of > or = 20% from the baseline value or an absolute value of <100 mmHg, whichever was higher." | 2.71 | Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anaesthesia for Caesarean section. ( Kansal, A; Kumar, P; Mohta, M; Sethi, AK; Tyagi, A, 2005) |
| "Therefore mephentermin is suitable for treatment of hypotension in pregnancy." | 1.26 | [Suitability of mephentermine for the management of arterial hypotension in pregnancy]. ( Lauckner, W; Retzke, U; Schwarz, R, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (71.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (12.50) | 29.6817 |
| 2010's | 4 (12.50) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Agarwal, S | 1 |
| Kumar, M | 1 |
| Gupta, A | 2 |
| Rautela, RS | 1 |
| Jain, N | 1 |
| Chakrabarti, D | 1 |
| N, GK | 1 |
| Masapu, D | 1 |
| Vimala, S | 1 |
| Unnikrishnan, P | 1 |
| Gautham, NS | 1 |
| Mohta, M | 4 |
| Agarwal, D | 3 |
| Gupta, LK | 2 |
| Tyagi, A | 4 |
| Sethi, AK | 4 |
| Makkar, JK | 1 |
| Wig, J | 1 |
| Janani, SS | 1 |
| WINSOR, T | 1 |
| HORSLEY, AW | 1 |
| ECKSTEIN, JW | 1 |
| WHITTINGTON, RM | 1 |
| BERNSTEIN, A | 1 |
| ROTHFELD, EL | 1 |
| ROBINS, B | 1 |
| COHEN, F | 1 |
| SIMON, F | 1 |
| PODOLSKY, S | 1 |
| WATTS, FB | 1 |
| Kansal, A | 1 |
| Kumar, P | 1 |
| Murali Krishna, T | 1 |
| Panda, NB | 1 |
| Batra, YK | 1 |
| Rajeev, S | 1 |
| Sharma, PL | 1 |
| Jans, B | 1 |
| Dusart, D | 1 |
| Lauckner, W | 1 |
| Schwarz, R | 1 |
| Retzke, U | 1 |
| Petrov, A | 1 |
| Levinson, G | 1 |
| Shnider, SM | 2 |
| Seige, K | 1 |
| Preuss, EG | 2 |
| Schneider, W | 2 |
| Schwartze, D | 1 |
| Müller, E | 1 |
| Mann, D | 1 |
| Lietz, W | 1 |
| Wiessner, W | 1 |
| Cucchiara, RF | 1 |
| Restall, CJ | 1 |
| Wadhwa, RK | 1 |
| Wadhwa, SR | 1 |
| Khurana, RC | 1 |
| Ralston, DH | 1 |
| DeLorimier, AA | 1 |
| Graham, JA | 1 |
| Ledingham, IM | 1 |
| Gleadle, RI | 1 |
| Linton, AL | 1 |
| Mörl, H | 1 |
| Bartusch, M | 1 |
| James, FM | 1 |
| Greiss, FC | 1 |
| Kemp, RA | 1 |
| Mills, LC | 1 |
| Moyer, JH | 1 |
| Brienza, A | 1 |
| De Leonardis, A | 1 |
| Friedberg, CK | 1 |
| Skinner, DB | 1 |
| Davis, WG | 1 |
| Camp, TF | 1 |
| Lawrence, RM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital[NCT05706727] | Phase 3 | 42 participants (Anticipated) | Interventional | 2023-03-23 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mephentermine and Blood Pressure, Low
| Article | Year |
|---|---|
THE TREATMENT OF SHOCK ACCOMPANYING MYOCARDIAL INFARCTION.
Topics: Cardiovascular Diseases; Humans; Hypotension; Mephentermine; Myocardial Infarction; Norepinephrine; | 1963 |
ESSENTIAL HYPOTENSION: A CLINICAL NONENTITY.
Topics: Adrenal Cortex Hormones; Angiotensins; Blood; Drug Therapy; Electrolytes; Hypokalemia; Hypotension; | 1964 |
Vasopressors in obstetrics.
Topics: Angiotensin II; Drug Synergism; Ephedrine; Epinephrine; Female; Humans; Hypotension; Isoproterenol; | 1974 |
6 trials available for mephentermine and Blood Pressure, Low
| Article | Year |
|---|---|
Effect of Intravenous Calcium Gluconate on Prevention of Post Spinal Hypotension during Spinal Anaesthesia for Caesarean Section: A Randomized Double-Blind Controlled Study.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Calcium; Calcium Gluconate; Cesarean Section; Double-Bl | 2022 |
Comparison of potency of ephedrine and mephentermine for prevention of post-spinal hypotension in caesarean section.
Topics: Adult; Anesthesia, Spinal; Cesarean Section; Double-Blind Method; Ephedrine; Female; Heart Rate; Hum | 2008 |
Comparison of phenylephrine hydrochloride and mephentermine sulphate for prevention of post spinal hypotension.
Topics: Adrenergic alpha-1 Receptor Agonists; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pres | 2010 |
Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anaesthesia for Caesarean section.
Topics: Adrenergic Agents; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Apgar Score; Cesarean Section | 2005 |
Combination of low doses of intrathecal ketamine and midazolam with bupivacaine improves postoperative analgesia in orthopaedic surgery.
Topics: Adjuvants, Anesthesia; Adult; Analgesics; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Doubl | 2008 |
[Mephentermine--a new circulation-active anti hypotensive drug].
Topics: Adolescent; Adult; Blood Circulation; Clinical Trials as Topic; Female; Humans; Hypotension; Male; M | 1972 |
23 other studies available for mephentermine and Blood Pressure, Low
| Article | Year |
|---|---|
Adverse Hemodynamic Event Due to Floseal Hemostatic Matrix Application.
Topics: Adrenergic alpha-1 Receptor Agonists; Adult; Embolism, Air; Female; Fluid Therapy; Gelatin Sponge, A | 2016 |
Intraoperative Seizures Presenting as Refractory Hypotension.
Topics: Dopamine; Dopamine Agents; Epinephrine; Female; Humans; Hypotension; Intraoperative Complications; M | 2017 |
Potency of mephentermine for prevention of post-spinal hypotension.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotension; M | 2009 |
Up-down study--is the analysis adequate?
Topics: Adult; Anesthesia, Spinal; Cesarean Section; Ephedrine; Female; Humans; Hypotension; Mephentermine; | 2010 |
Mephentermine sulfate for treatment of arterial hypotension.
Topics: Humans; Hypotension; Mephentermine | 1959 |
Hemodynamic responses to administration of mephentermine in normotensive and hypotensive dogs.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Cardiovascular System; Dogs; Hemodynamics; Hu | 1961 |
Mephentermine sulphate as a hypertensive agent in general practice.
Topics: Family Practice; General Practice; Humans; Hypertension; Hypotension; Mephentermine | 1963 |
MYOCARDIAL INFARCTION, GRAM-NEGATIVE BACTEREMIA, PROLONGED SHOCK, AND LEUKEMOID REACTION.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Bacteremia; Diagnosis; Drug Therapy; Enterobacter ae | 1965 |
Effect of propranolol on arterial hypotension induced by halothane in the dog under nitrous oxide anaesthesia.
Topics: Anesthesia, Inhalation; Animals; Dogs; Electric Countershock; Epinephrine; Halothane; Hypotension; M | 1967 |
[Thrombosis of both carotid arteries, arterial hypotension and cancer of the pancreas].
Topics: Aged; Carotid Artery Thrombosis; Ethanolamines; Etilefrine; Humans; Hypotension; Male; Mephentermine | 1979 |
[Suitability of mephentermine for the management of arterial hypotension in pregnancy].
Topics: Drug Evaluation; Female; Germany, East; Hemodynamics; Humans; Hypotension; Mephentermine; Pregnancy; | 1978 |
[Complications in the cardiovascular system from neuroleptic treatment].
Topics: Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular System; Dose | 1987 |
Mephentermine and intravenous fluids for the prevention of hypotension associated with spinal anesthesia.
Topics: Anesthesia, Spinal; Blood Pressure; Humans; Hypotension; Infusions, Parenteral; Male; Mephentermine; | 1973 |
Cardiovascular collapse unrelated to anaesthesia. An undiagnosed ectopic pregnancy.
Topics: Adult; Anesthesia, General; Blood Transfusion; Curettage; Dilatation; Female; Humans; Hypotension; K | 1974 |
Effects of equipotent ephedrine, metaraminol, mephentermine, and methoxamine on uterine blood flow in the pregnant ewe.
Topics: Acid-Base Equilibrium; Anesthesia, Local; Anesthesia, Obstetrical; Anesthesia, Spinal; Animals; Bloo | 1974 |
Treatment of intoxication with combinations of drugs and management of the associated shock.
Topics: Adult; Amobarbital; Chlordiazepoxide; Diuresis; Female; Humans; Hypotension; Mephentermine; Phenelzi | 1969 |
[Studies on drug controlled blood distribution as a conservative therapeutic principle in arteriosclerosis obliterans].
Topics: Administration, Oral; Arteriosclerosis Obliterans; Blood Circulation; Blood Pressure; Blood Volume; | 1972 |
An evaluation of vasopressor therapy for maternal hypotension during spinal anesthesia.
Topics: Anesthesia, Spinal; Animals; Cardiac Output; Ephedrine; Female; Hypotension; Mephentermine; Metarami | 1970 |
Indications for adrenergic stimulators in shock.
Topics: Blood Pressure; Blood Volume; Cardiac Output; Carotid Arteries; Central Venous Pressure; Cerebrovasc | 1971 |
[The choice of the pressor drug in hypotension caused by peridural anesthesia. Observations with methoxamine, metaraminol and mephentermine].
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotensi | 1967 |
Current status of the treatment of shock complicating acute myocardial infarction.
Topics: Digitalis Glycosides; Dopamine; Humans; Hydrocortisone; Hyperbaric Oxygenation; Hypotension; Isoprot | 1969 |
Left circumflex coronary artery division in dogs given supportive treatment.
Topics: Animals; Coronary Vessels; Dogs; Electric Countershock; Electrocardiography; Hypotension; Infusions, | 1969 |
Hypotension: its relation to epilepsy.
Topics: Adult; Electroencephalography; Epilepsy; Female; Humans; Hypotension; Mephentermine; Phenylephrine | 1966 |