mephenesin has been researched along with Parkinson Disease in 5 studies
Mephenesin: A centrally acting muscle relaxant with a short duration of action.
1-(2-methylphenyl)glycerol : A glycerol ether in which a single 2-methylphenyl group is attached at position 1 of glycerol via an ether linkage.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The most disabling form of Parkinsonism is that occurring after encephalitis." | 1.23 | Therapy of Parkinson's disease. ( VAN METER, JR, 1950) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| VAN METER, JR | 1 |
| JEUB, RP | 1 |
| Schmutzler, F | 1 |
| Eichhorn, A | 1 |
| Critchley, E | 1 |
| Loyning, Y | 1 |
1 review available for mephenesin and Parkinson Disease
| Article | Year |
|---|---|
[Antiparkinson agents. 50].
Topics: Atropine; Dihydroxyphenylalanine; Diphenhydramine; Histamine H1 Antagonists; Humans; Mephenesin; Mon | 1970 |
4 other studies available for mephenesin and Parkinson Disease
| Article | Year |
|---|---|
Therapy of Parkinson's disease.
Topics: Diphenhydramine; Encephalitis; Humans; Mephenesin; Muscle Rigidity; Pain; Parkinson Disease; Parkins | 1950 |
Clinical experience with mephenesin ("tolserol"; myanesin) in treatment of hyperkinetic disorders, with special reference to postencephalitic paralysis agitans.
Topics: Encephalitis; Encephalitis, Arbovirus; Epidemics; Mephenesin; Paralysis; Parkinson Disease; Parkinso | 1950 |
Clinical manifestations of essential tremor.
Topics: Adult; Aged; Amantadine; Ataxia; Chlordiazepoxide; Dihydroxyphenylalanine; Female; Humans; Male; Mep | 1972 |
[Centrally acting muscle relaxant drugs].
Topics: Chlormezanone; Dihydroxyphenylalanine; Humans; Mephenesin; Muscles; Muscular Diseases; Parasympathol | 1968 |