Compounds > mephenesin
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mephenesin and Clostridium tetani Infection

mephenesin has been researched along with Clostridium tetani Infection in 51 studies

Mephenesin: A centrally acting muscle relaxant with a short duration of action.
1-(2-methylphenyl)glycerol : A glycerol ether in which a single 2-methylphenyl group is attached at position 1 of glycerol via an ether linkage.

Research Excerpts

ExcerptRelevanceReference
"The anti-tetanus activities of chlorpromazine and mephenesin have been determined quantitatively in intact, spinal and decerebrate rabbits with local tetanus."7.64Site of action of chlorpromazine and mephenesin in experimental tetanus. ( WEBSTER, RA, 1962)
" The combination of phenobarbital and Tolserol(R) is very satisfactory in controlling the muscular rigidity and spasm in cases of moderately severe tetanus."7.63Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases. ( GODMAN, HE, 1951)
"The anti-tetanus activities of chlorpromazine and mephenesin have been determined quantitatively in intact, spinal and decerebrate rabbits with local tetanus."3.64Site of action of chlorpromazine and mephenesin in experimental tetanus. ( WEBSTER, RA, 1962)
"The anti-tetanus activity of a number of phenothiazine derivatives and other centrally acting muscle relaxants, such as mephenesin, dicyclopropyl ketoxime, 2-amino-6-methylbenzothiazole and meprobamate, has been determined in rabbits with experimental local tetanus."3.64Centrally acting muscle relaxants in tetanus. ( WEBSTER, RA, 1961)
" The combination of phenobarbital and Tolserol(R) is very satisfactory in controlling the muscular rigidity and spasm in cases of moderately severe tetanus."3.63Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases. ( GODMAN, HE, 1951)
"Local tetanus was induced in rabbits by the intramuscular injection of tetanus toxin."1.24A method of assaying the anti-tetanus potency of drugs on experimental local tetanus in the rabbit. ( LAURENCE, DR; WEBSTER, RA, 1958)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199050 (98.04)18.7374
1990's1 (1.96)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SMITH, WH1
BOWER, AG1
LOPES, O1
DIAZ-RIVERA, RS1
TRILLA, F1
PONS, ER1
FREIREICH, AW1
LUBART, A1
McCAFFREY, PE1
SAURIO, L1
HERNBORG, J1
PARKES, CM1
DOCHERTY, DF1
ADRIANI, J1
KERR, M1
MONDINI, PG3
BERTOLOTTO, R3
MURISON, AR1
GIBSON, LM1
HUTCHINSON, J1
HURRELL, GD1
LAURENCE, DR2
WEBSTER, RA4
ANDERSEN, EW2
NAVARATNE, RA1
HOUGS, W1
ULDALL, T1
HARRISON, GA1
ROSEN, M1
GOODALL, P1
KLOETZEL, K1
PINHEIRO, D1
NASSER, WK1
LLINAS, R1
MONTANT, R1
MOTTIRONI, G1
NEWHOUSE, ML1
ROCHFORD, JD1
ROYSTON, GR1
MOSELEY, V1
COLEMAN, RR1
ELLISON, H1
SANTEMMA, EE1
GRAHAM, GC1
NILSSON, E2
PLEWES, LW1
WILSON, D1
DAVISON, MH2
GODMAN, HE1
COLE, L1
GINZEL, KH2
TSCHABITSCHER, H1
WAYAND, E2
BANDI, W1
BOLES, TC1
SMITH, JH1
VERONESI, R1
MEIRA, JA1
KAHALY, R1
HARVIN, JR1
HAGBERG, S1
WALLENSTEN, S1
MacDONALD, WB1
WARD, AB1
PASK, EA1
TORRENS, JA1
EDWARDS, PM1
WOOD, MW1
Smitz, S1
Cohnen, AI1
Sadzot, B1
Joseph, A1
Pulimood, BM1
Leonardi, G1
Kretzschmar, R1
Meyer, HJ1
Teschendorf, HJ1
Zöllner, B1

Reviews

1 review available for mephenesin and Clostridium tetani Infection

ArticleYear
[Current directions in the treatment of tetanus].
    Recenti progressi in medicina, 1975, Volume: 58, Issue:1

    Topics: Benzodiazepines; Chlorpromazine; Diazepam; Humans; Hypnotics and Sedatives; Immunotherapy; Mephenesi

1975

Other Studies

50 other studies available for mephenesin and Clostridium tetani Infection

ArticleYear
Mephenesin in the treatment of tetanus.
    British medical journal, 1953, May-16, Volume: 1, Issue:4819

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1953
New therapy in a case of tetanus.
    California medicine, 1953, Volume: 78, Issue:5

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1953
[Case of concomitant tetanus and diphtheria].
    Anais paulistas de medicina e cirurgia, 1953, Volume: 65, Issue:4

    Topics: Diphtheria; Mephenesin; Tetanus; Tetanus Toxoid

1953
Muscular relaxation in tetanus with special reference to the effect of mephenesin.
    Annals of internal medicine, 1954, Volume: 40, Issue:3

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1954
Tetanus; report of two cases with recovery.
    New York state journal of medicine, 1954, May-15, Volume: 54, Issue:10

    Topics: Barbiturates; Biological Phenomena; Mephenesin; Physiological Phenomena; Tetanus; Tetanus Toxoid

1954
[A case of tetanus treated with myanecin].
    Duodecim; laaketieteellinen aikakauskirja, 1954, Volume: 70, Issue:4

    Topics: Mephenesin; Tetanus

1954
[Metabolic tests in tetanus].
    Nordisk medicin, 1954, Jun-17, Volume: 51, Issue:25

    Topics: Biochemical Phenomena; Mephenesin; Oxygen; Tetanus; Tetanus Toxoid

1954
Mephenesin and gallamine triethiodide in tetanus.
    British medical journal, 1954, Aug-21, Volume: 2, Issue:4885

    Topics: Cardiovascular Agents; Gallamine Triethiodide; Mephenesin; Muscle Relaxants, Central; Tetanus; Tetan

1954
Tetanus treated with intravenous mephenesin.
    Lancet (London, England), 1955, Feb-26, Volume: 268, Issue:6861

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1955
Mephenesin and combination of mephenesin and chlorpromazine in the management of tetanus: report of 100 cases.
    Southern medical journal, 1955, Volume: 48, Issue:8

    Topics: Chlorpromazine; Disease Management; Humans; Mephenesin; Tetanus

1955
[The modern therapy of tetanus: clinical contribution].
    Acta chirurgica Italica, 1955, Volume: 11, Issue:3

    Topics: Curare; Mephenesin; Tetanus; Tetanus Toxoid

1955
[Treatment of tetanus with alpha, beta-dihydroxy-gamma-(2-methylphenoxy) propane (relaxil); with six treated cases].
    Acta anaesthesiologica, 1955, Volume: 6, Issue:3

    Topics: Gamma Rays; Mephenesin; Propane; Tetanus; Tetanus Toxoid

1955
[Recent advances in tetanus therapy; clinical report].
    Minerva medica, 1957, Feb-10, Volume: 48, Issue:12

    Topics: Humans; Mephenesin; Tetanus

1957
Mephenesin in the treatment of tetanus: report of a case.
    Scottish medical journal, 1957, Volume: 2, Issue:7

    Topics: Mephenesin; Tetanus

1957
Management of tetanus, using chlorpromazine and mephenesin.
    British medical journal, 1958, Aug-16, Volume: 2, Issue:5093

    Topics: Chlorpromazine; Disease Management; Humans; Mephenesin; Tetanus; Tetanus Toxoid

1958
A method of assaying the anti-tetanus potency of drugs on experimental local tetanus in the rabbit.
    British journal of pharmacology and chemotherapy, 1958, Volume: 13, Issue:3

    Topics: Animals; Biological Assay; Electromyography; Injections, Intramuscular; Mephenesin; Rabbits; Tetanus

1958
The activity of a variety of chemical compounds against experimental tetanus.
    British journal of pharmacology and chemotherapy, 1958, Volume: 13, Issue:3

    Topics: Acepromazine; Anticonvulsants; Barbiturates; Central Nervous System; Central Nervous System Depressa

1958
Tetanus; a review of 356 cases with special reference to treatment with mephenesin.
    Acta anaesthesiologica Scandinavica, 1958, Volume: 2, Issue:2

    Topics: Mephenesin; Tetanus

1958
The action of mephenesin on local tetanus in rabbits.
    Acta pharmacologica et toxicologica, 1958, Volume: 14, Issue:4

    Topics: Animals; Lagomorpha; Mephenesin; Rabbits; Tetanus; Tetanus Toxoid

1958
[2 tetanus cases treated with intravenous Glykresin (mephenesin)].
    Ugeskrift for laeger, 1961, Jun-30, Volume: 123

    Topics: Mephenesin; Tetanus

1961
Site of action of chlorpromazine and mephenesin in experimental tetanus.
    British journal of pharmacology and chemotherapy, 1962, Volume: 18

    Topics: Animals; Chlorpromazine; Mephenesin; Rabbits; Spinal Cord; Tetanus; Tetanus Toxoid

1962
Centrally acting muscle relaxants in tetanus.
    British journal of pharmacology and chemotherapy, 1961, Volume: 17

    Topics: Animals; Mephenesin; Meprobamate; Muscle Relaxants, Central; Rabbits; Structure-Activity Relationshi

1961
HAEMORRHAGIC COMPLICATIONS DURING THE TREATMENT OF TETANUS.
    Lancet (London, England), 1964, Feb-29, Volume: 1, Issue:7331

    Topics: Amobarbital; Child; Chloramphenicol; Chlorpromazine; Diphenhydramine; Hematuria; Hemolysis; Hydrocor

1964
STUDIES ON THE CAUSE OF DEATH IN TETANUS; HUMAN TETANUS AS A RESPIRATORY PROBLEM.
    Diseases of the chest, 1964, Volume: 45

    Topics: Cause of Death; Death; Diaphragm; Humans; Mephenesin; Metabolism; Muscle Relaxants, Central; Patholo

1964
[THE USE OF TOLSEROL AS A MUSCLE RELAXANT IN THE TREATMENT OF TETANUS IN THE NEWBORN].
    Medicina contemporanea (Lisbon, Portugal), 1963, Volume: 81

    Topics: Humans; Infant, Newborn; Infant, Newborn, Diseases; Mephenesin; Tetanus; Tetanus Toxoid

1963
CLINICAL TETANUS: TREATMENT OF TEN CASES.
    The Journal of the Indiana State Medical Association, 1964, Volume: 57

    Topics: Chlorpromazine; Debridement; Desensitization, Immunologic; Erythromycin; Humans; Injections; Injecti

1964
MECHANSIMS OF SUPRASPINAL ACTIONS UPON SPINAL CORD ACTIVITIES. PHARMACOLOGICAL STUDIES ON RETICULAR INHIBITION OF ALPHA EXTENSOR MOTONEURONS.
    Journal of neurophysiology, 1964, Volume: 27

    Topics: Brain; Cats; Decerebrate State; Mephenesin; Motor Neurons; Neurons; Neurophysiology; Pharmacology; P

1964
[Observations on certain cases of tetanus].
    Schweizerische medizinische Wochenschrift, 1955, Jan-29, Volume: 85, Issue:5

    Topics: Mephenesin; Tetanus; Tetanus Toxoid; Trachea; Vaccination; Vaccines

1955
An unusual complication of myanesin therapy in the treatment of tetanus.
    British medical journal, 1950, Oct-28, Volume: 2, Issue:4686

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1950
Management of tetanus with mephenesin.
    Journal of the South Carolina Medical Association, 1950, Volume: 46, Issue:10

    Topics: Disease Management; Humans; Mephenesin; Tetanus

1950
Tolserol in tetanus.
    New York state journal of medicine, 1950, Nov-15, Volume: 50, Issue:22

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1950
[Myanesin therapy of tetanus].
    Nordisk medicin, 1950, May-12, Volume: 43, Issue:19

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1950
Two cases of tetanus treated with myanesin.
    Anaesthesia, 1951, Volume: 6, Issue:1

    Topics: Mephenesin; Tetanus

1951
Mephenesin in tetanus.
    Anesthesiology, 1951, Volume: 12, Issue:1

    Topics: Mephenesin; Tetanus

1951
Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases.
    California medicine, 1951, Volume: 74, Issue:2

    Topics: Mephenesin; Muscle Rigidity; Phenobarbital; Spasm; Tetanus; Tetanus Toxoid; Tracheotomy

1951
Curarine and myanesin in tetanus.
    Postgraduate medical journal, 1951, Volume: 27, Issue:303

    Topics: Curare; Humans; Mephenesin; Tetanus; Tubocurarine

1951
[Modern drug therapy of tetanus].
    Klinische Medizin; osterreichische Zeitschrift fur wissenschaftliche und praktische Medizin, 1951, Volume: 6, Issue:4

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1951
[Relaxil in tetanus].
    Schweizerische medizinische Wochenschrift, 1951, Mar-10, Volume: 81, Issue:10

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1951
Mephenesin in treatment of tetanus; results of oral administration in three cases.
    Journal of the American Medical Association, 1951, Aug-04, Volume: 146, Issue:14

    Topics: Administration, Oral; Mephenesin; Tetanus; Tetanus Toxoid

1951
[Considerations on the treatment of tetanus; results of the use of a new muscular relaxant drug (tolserol) in 40 cases].
    Arquivos de neuro-psiquiatria, 1951, Volume: 9, Issue:2

    Topics: Mephenesin; Tetanus

1951
Tetanus neonatorum-report of a case treated with mephenesin.
    Journal of the South Carolina Medical Association, 1952, Volume: 48, Issue:3

    Topics: Humans; Mephenesin; Sepsis; Tetanus

1952
[Continuous intravenous infusion of myanesin solution in low concentration in tetanus therapy].
    Svensk tandlakare tidskrift. Swedish dental journal, 1952, Feb-08, Volume: 49, Issue:6

    Topics: Glyceraldehyde; Infusions, Intravenous; Mephenesin; Pharmaceutical Solutions; Solutions; Tetanus; Te

1952
The modern symptomatic therapy of tetanus.
    Anesthesie et analgesie, 1952, Volume: 9, Issue:1

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1952
A case of severe tetanus treated with a continuous intravenous infusion of myanesin and sodium pentothal.
    The Medical journal of Australia, 1949, Oct-08, Volume: 2, Issue:15

    Topics: Barbital; Infusions, Intravenous; Mephenesin; Sodium; Tetanus; Thiopental

1949
Myanesin in the treatment of tetanus.
    British medical journal, 1949, Apr-09, Volume: 1, Issue:4605

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1949
Myanesin in tetanus.
    Lancet (London, England), 1948, Nov-20, Volume: 2, Issue:6534

    Topics: Mephenesin; Tetanus; Tetanus Toxoid

1948
Mephenesine in tetanus.
    Journal of the American Geriatrics Society, 1995, Volume: 43, Issue:7

    Topics: Administration, Topical; Aged; Aged, 80 and over; Female; Humans; Leg Injuries; Mephenesin; Tetanus

1995
Use of diazepam in tetanus--a comparative study.
    The Indian journal of medical research, 1978, Volume: 68

    Topics: Adolescent; Adult; Chlorpromazine; Diazepam; Drug Evaluation; Drug Therapy, Combination; Female; Hum

1978
[Antagonistic action of natural 5,6-hydrogenated Kava pyrones against strychnine poisoning and experimental local tetanus].
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: Anesthetics; Animals; Antidotes; Ataxia; Electromyography; Isonicotinic Acids; Male; Mephenesin; Mic

1969
Modern tetanus treatment.
    International anesthesiology clinics, 1966,Summer, Volume: 4, Issue:2

    Topics: Barbiturates; Chlorpromazine; Drug Hypersensitivity; Humans; Hyperbaric Oxygenation; Injections, Int

1966