meperidine has been researched along with Porphyrias in 4 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases." | 5.28 | Normeperidine-induced seizures in hereditary coproporphyria. ( Deeg, MA; Rajamani, K, 1990) |
| "It was made the warning that drug dependence will arise very easy in patients with porphyria." | 2.69 | [Social problems of porphyria]. ( Kostrzewska, E; Tarczyńska-Nosal, S, 1998) |
| "Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases." | 1.28 | Normeperidine-induced seizures in hereditary coproporphyria. ( Deeg, MA; Rajamani, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hofmann-von Bandel, J | 1 |
| Tarczyńska-Nosal, S | 1 |
| Kostrzewska, E | 1 |
| Deeg, MA | 1 |
| Rajamani, K | 1 |
| Herrick, AL | 1 |
| McColl, KE | 1 |
| Moore, MR | 1 |
| Cook, A | 1 |
| Goldberg, A | 1 |
2 trials available for meperidine and Porphyrias
| Article | Year |
|---|---|
[Social problems of porphyria].
Topics: Adult; Disability Evaluation; Female; Follow-Up Studies; Humans; Male; Mental Disorders; Meperidine; | 1998 |
Controlled trial of haem arginate in acute hepatic porphyria.
Topics: Acute Disease; Adolescent; Arginine; Clinical Trials as Topic; Double-Blind Method; Female; Heme; He | 1989 |
2 other studies available for meperidine and Porphyrias
| Article | Year |
|---|---|
[Methods of anesthesia in rare systemic diseases].
Topics: Adolescent; Anesthesia, General; Child; Diazepam; Epidermolysis Bullosa; Fracture Fixation, Internal | 1980 |
Normeperidine-induced seizures in hereditary coproporphyria.
Topics: Adult; Cholinesterase Inhibitors; Coproporphyrins; Female; Humans; Infant; Liver Diseases; Meperidin | 1990 |