meperidine has been researched along with Pain, Intractable in 26 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reports of seizures associated with meperidine have led to a growing reliance on intravenous morphine, usually with patient-controlled devices." | 5.30 | Low frequency of meperidine-associated seizures in sickle cell disease. ( Nadvi, SZ; Ravindranath, Y; Sarnaik, S, 1999) |
| "Ten patients with neuropathic cancer pain, not responding to conventional opioid therapy, were treated with continuous intrathecal administration of meperidine." | 1.33 | Plasma concentrations of meperidine and normeperidine following continuous intrathecal meperidine in patients with neuropathic cancer pain. ( Kruis, MR; van der Vegt, MH; van Kan, HJ; Vranken, JH, 2005) |
| "Insufficient knowledge about cancer pain on the part of physicians is an important factor responsible for ineffective cancer pain relief." | 1.33 | Physicians' knowledge about pharmacological management of cancer pain--with special reference on their prescribing responses to simulated patients with cancer pain. ( Ger, LP; Ho, ST; Lai, KH; Lee, MC; Sun, WZ; Wong, JO; Wu, HB, 2006) |
| " The dosing of the narcotic analgesics incorporates seldom-used, but well-published pharmacokinetics." | 1.30 | Oral narcotic protocol to reduce narcotic injections in refractory migraine patients. ( Adelman, JU; Von Seggern, RL, 1997) |
| "Reports of seizures associated with meperidine have led to a growing reliance on intravenous morphine, usually with patient-controlled devices." | 1.30 | Low frequency of meperidine-associated seizures in sickle cell disease. ( Nadvi, SZ; Ravindranath, Y; Sarnaik, S, 1999) |
| " Comparison of data from the two observation periods showed the following: Average relative bioavailability 0." | 1.28 | Bioavailability and analgesic effect of sustained release cetobemidone capsules in cancer patients with chronic pain of malignant origin. ( Andersen, LS; Kjaer, M; Nielsen, H; Olsen, FE; Philipsen, J; Velander, G, 1992) |
| "90 (SD) and the mean relative bioavailability of the mixture was slightly above 100%." | 1.27 | Analgesic effect and bioavailability of oral ketogan given as tablets or mixture to patients with chronic pain of malignant origin. ( Kjaer, M; Nielsen, H, 1988) |
| " These studies confirm the importance of clinical pharmacokinetic measurements in the investigation and treatment of patients with intractable pain." | 1.26 | Clinical pharmacokinetics applied to patients with intractable pain: studies with pethidine. ( Glynn, CJ; Mather, LE, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (57.69) | 18.7374 |
| 1990's | 6 (23.08) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gourlay, GK | 1 |
| Vranken, JH | 1 |
| van der Vegt, MH | 1 |
| van Kan, HJ | 1 |
| Kruis, MR | 1 |
| Akin Takmaz, S | 1 |
| Inan, N | 1 |
| Günal, S | 1 |
| Kaymak, C | 1 |
| Sakalli, M | 1 |
| Dikmen, B | 1 |
| Wu, HB | 1 |
| Lee, MC | 1 |
| Lai, KH | 1 |
| Ho, ST | 1 |
| Sun, WZ | 1 |
| Wong, JO | 1 |
| Ger, LP | 1 |
| Enig, B | 1 |
| Davis, AJ | 1 |
| Grabow, L | 1 |
| Romankiewicz, JA | 1 |
| Rankin, MA | 1 |
| Glynn, CJ | 3 |
| Mather, LE | 3 |
| Kjaer, M | 3 |
| Nielsen, H | 3 |
| Andersen, LS | 2 |
| Von Seggern, RL | 1 |
| Adelman, JU | 1 |
| Harvey, SC | 1 |
| O'Neil, MG | 1 |
| Pope, CA | 1 |
| Cuddy, BG | 1 |
| Duc, TA | 1 |
| Nadvi, SZ | 1 |
| Sarnaik, S | 1 |
| Ravindranath, Y | 1 |
| Dunn, EB | 1 |
| Wolfe, JJ | 1 |
| Grier, MR | 1 |
| Howard, M | 1 |
| Cohen, F | 1 |
| Cousins, MJ | 1 |
| Wilson, PR | 1 |
| Graham, JR | 1 |
| Pawl, RP | 1 |
| Maltbie, AA | 1 |
| Cavenar, JO | 1 |
| Sullivan, JL | 1 |
| Hammett, EB | 1 |
| Zung, WW | 1 |
| Olsen, FE | 1 |
| Philipsen, J | 1 |
| Velander, G | 1 |
| Plancarte, R | 1 |
| Patt, R | 1 |
| McCaffery, M | 1 |
| Krantz, T | 1 |
| Christensen, CB | 1 |
| Gallagher, RM | 1 |
1 review available for meperidine and Pain, Intractable
| Article | Year |
|---|---|
Advances in opioid pharmacology.
Topics: Analgesics, Opioid; Animals; Codeine; Dose-Response Relationship, Drug; Drug Administration Routes; | 2005 |
4 trials available for meperidine and Pain, Intractable
| Article | Year |
|---|---|
[Sublingual buprenorphine in the treatment of pain caused by cancer. Transition to buprenorphine from other opiates].
Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Clinical Trials as Topic; Female; Humans; Male; Mepe | 1983 |
[Pain treatment by sub or epidural opiate administration].
Topics: Anesthesia, Epidural; Female; Humans; Injections, Spinal; Male; Meperidine; Morphine; Narcotics; Pai | 1982 |
[Bioavailability and analgetic effect of sustained-release ketobemidone capsules in patients with chronic pain of cancer].
Topics: Adult; Analgesics, Opioid; Biological Availability; Capsules; Delayed-Action Preparations; Female; H | 1993 |
Analgesia and haloperidol: a hypothesis.
Topics: Analgesics; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dose-Response Relationship, Dru | 1979 |
21 other studies available for meperidine and Pain, Intractable
| Article | Year |
|---|---|
Plasma concentrations of meperidine and normeperidine following continuous intrathecal meperidine in patients with neuropathic cancer pain.
Topics: Aged; Analgesics, Opioid; Female; Humans; Injections, Spinal; Male; Meperidine; Middle Aged; Neoplas | 2005 |
Ketamine combined with morphine for the management of cancer pain in a patient with meperidine tolerance and addiction.
Topics: Adenocarcinoma; Adult; Analgesics; Drug Therapy, Combination; Drug Tolerance; Humans; Ketamine; Male | 2005 |
Physicians' knowledge about pharmacological management of cancer pain--with special reference on their prescribing responses to simulated patients with cancer pain.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Prescriptions; Female; Humans; Know | 2006 |
Pain q3h.
Topics: Adult; Back Pain; Ethics, Nursing; Humans; Male; Meperidine; Pain, Intractable; Substance-Related Di | 1980 |
Strong analgesics--Part II.
Topics: Butorphanol; Humans; Meperidine; Morphinans; Nursing Care; Pain, Intractable; Pentazocine | 1980 |
Use of drugs for pain with cancer patients.
Topics: Adult; Aged; Analgesics; Female; Humans; Hypnotics and Sedatives; Male; Meperidine; Middle Aged; Neo | 1982 |
Clinical pharmacokinetics applied to patients with intractable pain: studies with pethidine.
Topics: Administration, Oral; Adult; Biological Availability; Drug Tolerance; Female; Humans; Injections, In | 1982 |
The minimum effective analgetic blood concentration of pethidine in patients with intractable pain.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Meperidine; Metabolic | 1982 |
Oral narcotic protocol to reduce narcotic injections in refractory migraine patients.
Topics: Administration, Oral; Clinical Protocols; Emergency Service, Hospital; Female; Health Care Costs; Hu | 1997 |
Continuous intrathecal meperidine via an implantable infusion pump for chronic, nonmalignant pain.
Topics: Aged; Analgesics, Opioid; Back Pain; Female; Humans; Infusion Pumps, Implantable; Infusions, Parente | 1997 |
Low frequency of meperidine-associated seizures in sickle cell disease.
Topics: Adolescent; Anemia, Sickle Cell; Female; Humans; Infant; Infant, Newborn; Injections, Intravenous; M | 1999 |
Finding an optimal dose: considerations in accurate opioid dispensing.
Topics: Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Male; Medication Errors; Meperid | 2000 |
Beliefs and values associated with administering narcotic analgesic to terminally ill patients.
Topics: Analgesics, Opioid; Attitude of Health Personnel; Decision Making; Female; Humans; Male; Meperidine; | 1979 |
Selective spinal analgesia.
Topics: Analgesia; Anesthesia, Epidural; Epidural Space; Humans; Injections, Spinal; Meperidine; Pain, Intra | 1979 |
Percutaneous radiofrequency electrocoagulation in the control of chronic pain.
Topics: Back Pain; Electrocoagulation; Equipment and Supplies; Humans; Lumbosacral Region; Meperidine; Metho | 1975 |
Bioavailability and analgesic effect of sustained release cetobemidone capsules in cancer patients with chronic pain of malignant origin.
Topics: Adult; Aged; Analgesics, Opioid; Biological Availability; Capsules; Delayed-Action Preparations; Fem | 1992 |
Intractable upper body pain in a pediatric patient relieved with cervical epidural opioid administration.
Topics: Analgesia, Epidural; Child, Preschool; Droperidol; Eye Neoplasms; Female; Humans; Meperidine; Pain, | 1991 |
Giving meperidine for pain: should it be so mechanical?
Topics: Analgesics, Opioid; Humans; Meperidine; Pain, Intractable | 1987 |
Analgesic effect and bioavailability of oral ketogan given as tablets or mixture to patients with chronic pain of malignant origin.
Topics: Administration, Oral; Adult; Aged; Allylamine; Amines; Drug Combinations; Female; Half-Life; Humans; | 1988 |
Respiratory depression after intrathecal opioids. Report of a patient receiving long-term epidural opioid therapy.
Topics: Dura Mater; Humans; Injections, Epidural; Male; Medication Errors; Meperidine; Middle Aged; Morphine | 1987 |
Emergency treatment of intractable migraine.
Topics: Adult; Dexamethasone; Dihydroergotamine; Drug Therapy, Combination; Female; Humans; Male; Meperidine | 1986 |