meperidine has been researched along with Migraine Disorders in 20 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anti-nauseant hydroxyzine (H) was coadministered in both treatment groups." | 5.08 | Double-blind, multicenter trial to compare the efficacy of intramuscular dihydroergotamine plus hydroxyzine versus intramuscular meperidine plus hydroxyzine for the emergency department treatment of acute migraine headache. ( Barton, CW; Carleton, SC; Chelly, JE; Chudnofsky, CR; Johnson, G; Morris, DL; Pietrzak, MP; Rhee, KJ; Rosenberg, J; Shesser, RF; Starkman, S; Van Valen, MK, 1998) |
| "Forty-seven adult patients with migraines enrolled on 50 visits." | 2.67 | Ketorolac versus meperidine and hydroxyzine in the treatment of acute migraine headache: a randomized, prospective, double-blind trial. ( Aldag, J; Duarte, C; Dunaway, F; Frederick, R; Turner, L, 1992) |
| "Consecutive adult patients with migraine who met eligibility criteria." | 2.67 | Methotrimeprazine versus meperidine and dimenhydrinate in the treatment of severe migraine: a randomized, controlled trial. ( Beilby, WJ; Dufour, DG; Moher, D; Smith, NA; Stiell, IG; Yen, M, 1991) |
| "The chlorpromazine was repeated every 15 minutes as needed up to a total of three doses." | 2.66 | Comparative efficacy of chlorpromazine and meperidine with dimenhydrinate in migraine headache. ( Baggoley, CJ; Lane, PL; McLellan, BA, 1989) |
| "Meperidine was less effective than dihydroergotamine at providing headache relief (OR=0." | 2.44 | The relative efficacy of meperidine for the treatment of acute migraine: a meta-analysis of randomized controlled trials. ( Friedman, BW; Friedman, MS; Hochberg, ML; Kapoor, A; Rowe, BH, 2008) |
| "Treatment of acute migraine headache with narcotics is potentially ineffective and may lead to abuse." | 2.42 | Use of narcotic analgesics in the emergency department treatment of migraine headache. ( Colman, I; Rothney, A; Rowe, BH; Wright, SC; Zilkalns, B, 2004) |
| "Data concerning status migrainosus in children and adolescents is sparse." | 1.31 | Status migrainosus in children and adolescents. ( Akhtar, ND; Murray, MA; Rothner, AD, 2001) |
| " The dosing of the narcotic analgesics incorporates seldom-used, but well-published pharmacokinetics." | 1.30 | Oral narcotic protocol to reduce narcotic injections in refractory migraine patients. ( Adelman, JU; Von Seggern, RL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedman, BW | 1 |
| Kapoor, A | 1 |
| Friedman, MS | 1 |
| Hochberg, ML | 1 |
| Rowe, BH | 2 |
| Vinson, DR | 1 |
| Hurtado, TR | 1 |
| Vandenberg, JT | 1 |
| Banwart, L | 1 |
| Gupta, R | 1 |
| Gernsheimer, J | 1 |
| Colman, I | 1 |
| Rothney, A | 1 |
| Wright, SC | 1 |
| Zilkalns, B | 1 |
| Moore, D | 1 |
| Scherl, ER | 1 |
| Wilson, JF | 1 |
| Davis, CP | 1 |
| Torre, PR | 1 |
| Williams, C | 1 |
| Gray, C | 1 |
| Barrett, K | 1 |
| Krucke, G | 1 |
| Peake, D | 1 |
| Bass, B | 1 |
| Von Seggern, RL | 1 |
| Adelman, JU | 1 |
| Linbo, L | 1 |
| Bartleson, JD | 1 |
| Morgan-Thompson, D | 1 |
| Greff, L | 1 |
| Naessens, JM | 1 |
| Carleton, SC | 1 |
| Shesser, RF | 1 |
| Pietrzak, MP | 1 |
| Chudnofsky, CR | 1 |
| Starkman, S | 1 |
| Morris, DL | 1 |
| Johnson, G | 1 |
| Rhee, KJ | 1 |
| Barton, CW | 1 |
| Chelly, JE | 1 |
| Rosenberg, J | 1 |
| Van Valen, MK | 1 |
| Ahmed, DS | 1 |
| Fecik, S | 1 |
| Kelly, AM | 1 |
| Rubsamen, DS | 1 |
| Akhtar, ND | 1 |
| Murray, MA | 1 |
| Rothner, AD | 1 |
| Richman, PB | 1 |
| Allegra, J | 1 |
| Eskin, B | 1 |
| Doran, J | 1 |
| Reischel, U | 1 |
| Kaiafas, C | 1 |
| Nashed, AH | 1 |
| Larkin, GL | 1 |
| Prescott, JE | 1 |
| Duarte, C | 1 |
| Dunaway, F | 1 |
| Turner, L | 1 |
| Aldag, J | 1 |
| Frederick, R | 1 |
| Stiell, IG | 1 |
| Dufour, DG | 1 |
| Moher, D | 1 |
| Yen, M | 1 |
| Beilby, WJ | 1 |
| Smith, NA | 1 |
| Lane, PL | 1 |
| McLellan, BA | 1 |
| Baggoley, CJ | 1 |
| Gallagher, RM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872] | Phase 4 | 500 participants (Actual) | Interventional | 2017-09-05 | Terminated (stopped due to no longer recruiting or studying) | ||
| IM Ketorolac vs Diclofenac Potassium Powder for Oral Solution (Cambia) for the Acute Treatment of Severe Migraine[NCT02664116] | Phase 4 | 40 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for meperidine and Migraine Disorders
| Article | Year |
|---|---|
The relative efficacy of meperidine for the treatment of acute migraine: a meta-analysis of randomized controlled trials.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dihydroergota | 2008 |
Use of narcotic analgesics in the emergency department treatment of migraine headache.
Topics: Adult; Aged; Alberta; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Drug Therapy, Combi | 2004 |
8 trials available for meperidine and Migraine Disorders
| Article | Year |
|---|---|
Comparison of dihydroergotamine with metoclopramide versus meperidine with promethazine in the treatment of acute migraine.
Topics: Acute Disease; Adult; Ambulatory Care; Dihydroergotamine; Double-Blind Method; Drug Combinations; Fe | 1995 |
Ketorolac versus meperidine-plus-promethazine treatment of migraine headache: evaluations by patients.
Topics: Adult; Analgesics, Non-Narcotic; Double-Blind Method; Drug Combinations; Female; Humans; Ionophores; | 1995 |
Double-blind, multicenter trial to compare the efficacy of intramuscular dihydroergotamine plus hydroxyzine versus intramuscular meperidine plus hydroxyzine for the emergency department treatment of acute migraine headache.
Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Dihydro | 1998 |
A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache.
Topics: Adult; Akathisia, Drug-Induced; Analgesics, Opioid; Antiemetics; Antipsychotic Agents; Droperidol; F | 2002 |
A randomized, double-blind, comparative study of the efficacy of ketorolac tromethamine versus meperidine in the treatment of severe migraine.
Topics: Acute Disease; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Emergencies; F | 1992 |
Ketorolac versus meperidine and hydroxyzine in the treatment of acute migraine headache: a randomized, prospective, double-blind trial.
Topics: Acute Disease; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Female; Humans | 1992 |
Methotrimeprazine versus meperidine and dimenhydrinate in the treatment of severe migraine: a randomized, controlled trial.
Topics: Adolescent; Adult; Dimenhydrinate; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; | 1991 |
Comparative efficacy of chlorpromazine and meperidine with dimenhydrinate in migraine headache.
Topics: Adult; Chlorpromazine; Dimenhydrinate; Double-Blind Method; Drug Therapy, Combination; Female; Human | 1989 |
10 other studies available for meperidine and Migraine Disorders
| Article | Year |
|---|---|
Variations among emergency departments in the treatment of benign headache.
Topics: Adolescent; Adult; Aged; Algorithms; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Bino | 2003 |
Treating headache in the emergency ward: avoiding the migraine-meperidine trap.
Topics: Diagnosis, Differential; Emergency Service, Hospital; Headache; Humans; Meperidine; Migraine Disorde | 2003 |
Tales from the 'Flying Doctor'.
Topics: Adult; Aircraft; Australia; Female; Fractures, Bone; Health Services; Hematoma, Subdural; Humans; Ma | 1984 |
Oral narcotic protocol to reduce narcotic injections in refractory migraine patients.
Topics: Administration, Oral; Clinical Protocols; Emergency Service, Hospital; Female; Health Care Costs; Hu | 1997 |
Acute treatment of periodic severe headache: comparison of three outpatient care facilities.
Topics: Acute Disease; Adult; Ambulatory Care; Ambulatory Care Facilities; Analgesics, Opioid; Cost-Benefit | 1998 |
MAOIs: still here, still dangerous.
Topics: Aged; Analgesics, Opioid; Antidepressive Agents; Contraindications; Depression; Drug Interactions; F | 2000 |
Migraine: pharmacotherapy in the emergency department.
Topics: Analgesics, Opioid; Antipsychotic Agents; Emergency Service, Hospital; Emergency Treatment; Haloperi | 2000 |
Home use of Demerol for migraine.
Topics: Ambulatory Care; Drug Overdose; Female; Humans; Malpractice; Meperidine; Middle Aged; Migraine Disor | 1999 |
Status migrainosus in children and adolescents.
Topics: Adolescent; Child; Diagnosis, Differential; Dihydroergotamine; Drug Therapy, Combination; Female; Fo | 2001 |
Emergency treatment of intractable migraine.
Topics: Adult; Dexamethasone; Dihydroergotamine; Drug Therapy, Combination; Female; Humans; Male; Meperidine | 1986 |