meperidine has been researched along with Metabolic Acidosis in 18 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Meperidine is an effective method of reducing the elevated metabolic demand of shivering." | 1.27 | Effect of meperidine on oxygen consumption, carbon dioxide production, and respiratory gas exchange in postanesthesia shivering. ( Dwersteg, JF; Macintyre, PE; Pavlin, EG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (83.33) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Green, C | 1 |
| DAWSON, GR | 1 |
| MARKELLO, R | 1 |
| KING, BD | 1 |
| Sosa, CG | 1 |
| Buekens, P | 1 |
| Hughes, JM | 1 |
| Balaguer, E | 1 |
| Sotero, G | 1 |
| Panizza, R | 1 |
| Piriz, H | 1 |
| Alonso, JG | 1 |
| Thornton, S | 1 |
| Charlton, L | 1 |
| Murray, BJ | 1 |
| Davison, JM | 1 |
| Baylis, PH | 1 |
| Duck, HJ | 1 |
| Trenckmann, H | 1 |
| Fleischmann, JH | 1 |
| Neugebauer, A | 1 |
| Schauer, J | 1 |
| Thomas, G | 1 |
| Blackwell, RJ | 1 |
| Macintyre, PE | 1 |
| Pavlin, EG | 1 |
| Dwersteg, JF | 1 |
| Kariniemi, V | 1 |
| Rosti, J | 1 |
| Clark, RB | 1 |
| Pearson, JF | 1 |
| Davies, P | 1 |
| Rooth, G | 1 |
| McBride, R | 1 |
| Ivy, BJ | 1 |
| Thalme, B | 1 |
| Belfrage, P | 1 |
| Raabe, N | 1 |
| Wood, DW | 1 |
| Downes, JJ | 1 |
| Lecks, HI | 1 |
| Relton, JE | 1 |
| Divekar, VM | 1 |
| Phillips, TJ | 1 |
| Macdonald, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is There Any Effect of Meperidine on the Length of Duration of Labor? A Prospective Randomized Controlled Trial.[NCT01555671] | Phase 4 | 250 participants (Actual) | Interventional | 2012-01-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The period of time until the birth of the baby, since the patient being followed for delivery (NCT01555671)
Timeframe: 24h
| Intervention | minutes (Mean) |
|---|---|
| Meperidine Administration Group | 24 |
| Plasebo Group | 27 |
The primary outcome is to evaluate whether meperidine is effective in shortening the duration of the active phase of labor (NCT01555671)
Timeframe: 24h
| Intervention | minutes (Mean) |
|---|---|
| Meperidine Administration Group | 249 |
| Plasebo Group | 304 |
Total time of delivery of patients who gave birth including the second stage of delivery (NCT01555671)
Timeframe: 24h
| Intervention | minutes (Mean) |
|---|---|
| Meperidine Administration Group | 273 |
| Plasebo Group | 331 |
2 reviews available for meperidine and Metabolic Acidosis
| Article | Year |
|---|---|
Pethidine use: the ethics.
Topics: Acidosis; Adult; Analgesics, Opioid; Ethics, Nursing; Europe; Female; Fetal Blood; Health Knowledge, | 2008 |
Analgesia during labor: effect on the fetus and neonate.
Topics: Acidosis; Alphaprodine; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics; Apgar Score; B | 1974 |
2 trials available for meperidine and Metabolic Acidosis
| Article | Year |
|---|---|
Effect of pethidine administered during the first stage of labor on the acid-base status at birth.
Topics: Acid-Base Equilibrium; Acidosis; Analgesics, Opioid; Female; Fetal Blood; Hospitals, Public; Humans; | 2006 |
Comparative effect of pethidine, trichloroethylene, and Entonox on fetal and neonatal acid-base and PO2.
Topics: Acid-Base Equilibrium; Acidosis; Anesthesia, Obstetrical; Apgar Score; Carbon Dioxide; Female; Fetus | 1971 |
14 other studies available for meperidine and Metabolic Acidosis
| Article | Year |
|---|---|
A CASE OF POST-OPERATIVE APNOEA RESPONDING TO INTRAVENOUS SODIUM BICARBONATE INFUSION.
Topics: Acidosis; Apnea; Atropine; Bicarbonates; Bis-Trimethylammonium Compounds; Gallamine Triethiodide; Hu | 1964 |
PRACTICALITY OF HALOTHANE-AIR ANESTHESIA.
Topics: Acidosis; Anesthesia; Anesthesia, Inhalation; Biomedical Research; Blood Gas Analysis; Equipment and | 1964 |
The effect of early labour, maternal analgesia and fetal acidosis on fetal plasma oxytocin concentrations.
Topics: Acidosis; Adult; Analgesia, Obstetrical; Cesarean Section; Female; Fetal Blood; Fetal Diseases; Huma | 1993 |
[Drug therapy of myocardial infarct in ambulatory practice].
Topics: Acidosis; Adrenergic beta-Antagonists; Aftercare; Ajmaline; Ambulatory Care; Anticoagulants; Arrhyth | 1975 |
The analysis of continuous fetal heart rate traces in the first and second stages of labour.
Topics: Acidosis; Apgar Score; Chlormethiazole; Electrocardiography; Female; Fetal Distress; Fetal Heart; He | 1975 |
Effect of meperidine on oxygen consumption, carbon dioxide production, and respiratory gas exchange in postanesthesia shivering.
Topics: Acidosis; Anesthesia, General; Carbon Dioxide; Female; Humans; Male; Meperidine; Oxygen Consumption; | 1987 |
Intramuscular pethidine (meperidine) during labor associated with metabolic acidosis in the newborn.
Topics: Acidosis; Anesthesia, Obstetrical; Female; Fetal Blood; Humans; Infant, Newborn; Injections, Intramu | 1986 |
The effect of continuous lumbar epidural analgesia upon fetal acid-base status during the second stage of labour.
Topics: Acid-Base Equilibrium; Acidosis; Anesthesia, Epidural; Blood; Female; Fetus; Humans; Hydrogen-Ion Co | 1974 |
Fetal and maternal pH measurements. A basis for common normal values.
Topics: Acid-Base Equilibrium; Acidosis; Alberta; Amniotic Fluid; Anesthesia, Obstetrical; Apgar Score; Auto | 1973 |
Lumbar epidural analgesia in labour. I. Acid-base balance and clinical condition of mother, fetus and newborn child.
Topics: Acidosis; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood; Body Temperature; Bradycardia | 1974 |
The management of respiratory failure in childhood status asthmaticus. Experience with 30 episodes and evolution of a technique.
Topics: Acid-Base Equilibrium; Acidosis; Asthma; Blood Gas Analysis; Cardiac Tamponade; Child; Chlorpromazin | 1968 |
Malignant hyperpyrexia: clinical aspects.
Topics: Acidosis; Acidosis, Respiratory; Anesthesia, General; Anesthetics; Bicarbonates; Fever; Humans; Mepe | 1971 |
Malignant hyperpyrexia and anaesthesia.
Topics: Acidosis; Anesthesia, General; Atropine; Body Temperature; Creatine Kinase; Drug Synergism; Fever; H | 1971 |
Malignant hyperpyrexial deaths in a family.
Topics: Acidosis; Anesthesia, General; Child; Fever; Humans; Meperidine; Scopolamine; Thiopental | 1971 |