meperidine has been researched along with Long QT Syndrome in 1 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Meperidine treatment causes ECG changes (QTc-interval prolongation) in high correlation with normeperidine plasma concentration." | 1.46 | Meperidine-induced QTc-interval prolongation: prevalence, risk factors, and correlation to plasma drug and metabolite concentrations . ( Di Girolamo, G; Diez, RA; Fernández, N; Keller, GA; Olivera, NM; Quiroga, PN; Villa Etchegoyen, MC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keller, GA | 1 |
| Villa Etchegoyen, MC | 1 |
| Fernández, N | 1 |
| Olivera, NM | 1 |
| Quiroga, PN | 1 |
| Diez, RA | 1 |
| Di Girolamo, G | 1 |
1 other study available for meperidine and Long QT Syndrome
| Article | Year |
|---|---|
Meperidine-induced QTc-interval prolongation: prevalence, risk factors, and correlation to plasma drug and metabolite concentrations
.
Topics: Action Potentials; Aged; Aged, 80 and over; Analgesics, Opioid; Argentina; Biotransformation; Electr | 2017 |