meperidine has been researched along with Liver Diseases in 10 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases." | 5.28 | Normeperidine-induced seizures in hereditary coproporphyria. ( Deeg, MA; Rajamani, K, 1990) |
| "Pain was the most common complication, although use of analgesia after 2 hours of observation was low." | 1.35 | Post-procedure surveillance in liver biopsy: how long is long enough? ( Basford, P; Bell, M; Derrett, S; Howard, R; Karageorge, G; Schultz, M; van Harselaar, K, 2008) |
| "Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases." | 1.28 | Normeperidine-induced seizures in hereditary coproporphyria. ( Deeg, MA; Rajamani, K, 1990) |
| " When the drug was given intramuscularly its rate of absorption was very slow (57." | 1.28 | The effect of clinical hepatic disease on the distribution and elimination of pethidine administered post-operatively to dogs. ( Kalthum, W; Waterman, AE, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, A | 1 |
| Alansari, M | 1 |
| Lubcke, R | 1 |
| Schlup, M | 1 |
| Williams, M | 1 |
| Fraser, M | 1 |
| Buckingham, S | 1 |
| Schultz, M | 2 |
| Howard, R | 1 |
| Karageorge, G | 1 |
| van Harselaar, K | 1 |
| Bell, M | 1 |
| Basford, P | 1 |
| Derrett, S | 1 |
| DUNDEE, JW | 1 |
| TINCKLER, LF | 1 |
| Schenker, S | 2 |
| Hoyumpa, AM | 1 |
| Wilkinson, GR | 1 |
| Deeg, MA | 1 |
| Rajamani, K | 1 |
| Waterman, AE | 1 |
| Kalthum, W | 1 |
| Herrick, AL | 1 |
| McColl, KE | 1 |
| Moore, MR | 1 |
| Cook, A | 1 |
| Goldberg, A | 1 |
| McHorse, TS | 1 |
| Klotz, U | 1 |
| Wilkinson, G | 1 |
| Trachtenberg, HA | 1 |
1 review available for meperidine and Liver Diseases
| Article | Year |
|---|---|
The effect of parenchymal liver disease on the disposition and elimination of sedatives and analgesics.
Topics: Analgesics; Anti-Anxiety Agents; Barbiturates; Diazepam; Half-Life; Hepatitis; Humans; Hypnotics and | 1975 |
2 trials available for meperidine and Liver Diseases
| Article | Year |
|---|---|
Use of pethidine for percutaneous liver biopsy - a randomised, placebo-controlled, double blind study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biopsy; Double-Blind Method; Female; | 2015 |
Controlled trial of haem arginate in acute hepatic porphyria.
Topics: Acute Disease; Adolescent; Arginine; Clinical Trials as Topic; Double-Blind Method; Female; Heme; He | 1989 |
7 other studies available for meperidine and Liver Diseases
| Article | Year |
|---|---|
Post-procedure surveillance in liver biopsy: how long is long enough?
Topics: Adult; Aged; Analgesics, Opioid; Biopsy; Central Nervous System Depressants; Continuity of Patient C | 2008 |
Pethidine and liver damage.
Topics: Abdominal Injuries; Humans; Liver Diseases; Meperidine | 1952 |
PETHIDINE and the liver.
Topics: Humans; Liver Diseases; Meperidine | 1952 |
Normeperidine-induced seizures in hereditary coproporphyria.
Topics: Adult; Cholinesterase Inhibitors; Coproporphyrins; Female; Humans; Infant; Liver Diseases; Meperidin | 1990 |
The effect of clinical hepatic disease on the distribution and elimination of pethidine administered post-operatively to dogs.
Topics: Animals; Dog Diseases; Dogs; Female; Half-Life; Injections, Intramuscular; Injections, Intravenous; | 1990 |
Impaired elimination of meperidine in patients with liver disease.
Topics: Acute Disease; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Biotransformatio | 1974 |
Anesthesia for the patient with hepatic disease.
Topics: Anesthetics; Anesthetics, Local; Barbiturates; Humans; Liver Diseases; Meperidine; Morphine; Succiny | 1970 |